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Thread: Vitamin C, Cortisol Control and PCT

  1. #1
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    Vitamin C, Cortisol Control and PCT

    During PCT cortisol is a big problem and should be reduced at all costs. Its efftcts on destroying muscle are fairly dramatic and moreso post exercise.

    Cortisol is a catabolic hormone thats produced by the adrenal glands, moreso post exercise. Combine that with it already being elevated during times of PCT, whilst endogenous testosterone is low is the worst case possible scenerio.

    There are many products on the market (and I dont know how effective they are) that claim to reduce cortisol. But, the cheapest and best priced has to be our good old friend, Vitamin C.

    I've been doing some digging on using Vitamin C for this purpose and have found some fairly good studies on it and how it can benifit us bodybuilders, or anyone during PCT.

    Cortisol is elevated during times of stress, this includes both weight/resistance training AND cardio. The below study is done on long distance endurance activites, that isnt to say it cant be translated into weight/resistance training or times of stress.


    1: J Sports Med Phys Fitness. 2008 Jun;48(2):217-24.Links
    Effect of vitamin C supplementation on lipid peroxidation, muscle damage and inflammation after 30-min exercise at 75% VO2max.Nakhostin-Roohi B, Babaei P, Rahmani-Nia F, Bohlooli S.
    Department of Exercise Physiology, Guilan University, Rasht, Iran [email protected].

    AIM: Hypothetically, supplementation with the antioxidant vitamins C could alleviate exercise-induced lipid peroxidation. The purpose of this study was to evaluate the effect of vitamin C supplementation on exercise-induced lipid peroxidation, muscle damage and inflammation. METHODS: Sixteen healthy untrained male volunteers participated in a 30-min exercise at 75% Vo2max. Subjects were randomly assigned to one of two groups: 1) placebo and 2) vitamin C (VC: 1 000 mg vitamin C). Blood samples were obtained prior to supplementation (baseline), 2 h after supplementation (immediately pre-exercise), post-exercise, 2 and 24 h after exercise. Plasma levels of VC, total antioxidant capacity (TAC), creatine kinase (CK), malondealdehyde (MDA), total leukocytes, neutrophils, lymphocytes, interleukin-6 (IL-6) and cortisol were measured. RESULTS: Plasma vitamin C concentrations increased significantly in the VC in response to supplementation and exercise (P<0.05). TAC decreased significantly in Placebo group 24 h after exercise compared to pre-exercise (P<0.05). Although MDA levels were similar between groups at baseline, it increased significantly 2 h after exercise only in the Placebo group (P<0.05). CK increased immediately and 2 h after exercise in both groups and 24 h after exercise only in placebo group compared to pre-exercise (P<0.05). Markers of inflammation (total leukocyte counts, neutrophil counts and IL-6) were increased significantly in response to the exercise (P<0.05). In VC group, there was significant increase in lymphocyte counts immediately after exercise compared with pre-exercise (P<0.05). Serum cortisol concentrations significantly declined after supplementation compared with baseline (P<0.05) as well as declined 2 and 24 h after exercise compared with immediately after exercise in VC group (P<0.05). CONCLUSION: VC supplementation prevented endurance exercise-induced lipid peroxidation and muscle damage but had no effect on inflammatory markers.




    Not many PCT's contain a cortisol reduced and they should! I'll be updating my PCT thread to include one. I may even add a cortisol reducing supplement if one is worthy!

    Some may disagree that Vitamin C does not help, but it should still be a stable in your diet anyhow. Whether you take it in your multi-vitamin or consume enough of it daily from various fruits, so it cant hurt.

    I'd advise users to take around 1-3g/ED of Vit C for its effects on cortisol and for its overall health benifits. Take 1g apon awakening with all your other vits/supps/minerslas etc...And a further 1-2g PWO.
    Other cortisol reducers include, DHEA and 7-keto-DHEA. There are also supplements marketed to reduce cortisol, such as Primordial Performances EndoAmp and Anabolic Extreme's Retain.
    Last edited by Swifto; 05-09-2009 at 07:22 AM.

  2. #2
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    As always great post lol....

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    Bump

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    Can women use DHEA for cortisol control? Also very good write-up. I've heard it takes upwards of a few grams of Vitamin C to effectively reduce cortisol. I've personally been taking 3g in the AM upon waking, and 2-3g PWO.

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    im a firm believer in mega dosing vit c for many reasons/purposes. i take 8-12g of vit c a day. and swear by it. ive gotten many friends to do so and they also swear by it.

    its affects on immune system, energy, cortisol, joint pain etc have all been studied and shown to be affective.

    there a few good threads out there about mega dosing vit c.

    so yes... i def agree with this post. nice one marcus

  6. #6
    Nice Post!! I also plan to use Phosphatidyl Serine and L-Tyrosine for cortisol control. I've read quite a bit about both and we use use L-Tyrosine in our company to reduce stress induced cortisol in our clients.

    Vitamin C should be called the miracle vitamin.

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    Quote Originally Posted by dukkitdalaw View Post
    im a firm believer in mega dosing vit c for many reasons/purposes. i take 8-12g of vit c a day. and swear by it. ive gotten many friends to do so and they also swear by it.

    its affects on immune system, energy, cortisol, joint pain etc have all been studied and shown to be affective.

    there a few good threads out there about mega dosing vit c.

    so yes... i def agree with this post. nice one marcus
    Vit C will lower corticol during resistance training and post cardio. But it may also inhibit the recovery of muscle function post workout.

  8. #8
    In what form are you guys ingesting the Vitamin C? Capsules or powder? Empty stomach or with food? I would highly recommend using Animal Pak. I have started training earlier in the days now so that when I eat my first meal I take my Pak and wait about one hour and hit the weights...I noticed my workout intensity has gone up since I have added this Mega Vitamin/Mineral into my regime. Oh and be prepared for some glowing neon yellow urine! This is due to the body excreting the unused vitamins (mostly the b-complex) Forget to flush when at a friends house and be prepared for the reactions! LOL

  9. #9
    Here is the nutritional data for the Paks... appears to have 1gram Vitamin C per pak. I would supplement additional C for its health benefits...
    15 Paks
    Supplement Facts
    Serving Size2Packs
    Servings Per Container7.5
    Amount Per Serving % DV
    Calories 40
    Total Carbohydrates 4g <2%*
    Dietary Fiber 2g 8%*
    Protein 6g 12%*
    Vitamin A (As Carotenoids [B-Carotene, A-Carotene], Acetate) 9900IU 198%
    Vitamin C(as Ascorbic Acid, Ascorbyl Palmitate) 1g 1667%
    Vitamin D(as Cholecalciferol) 680IU 170%
    Vitamin E(as D-A, D-B, D-Y, D-A Tocopherols & Tocotrienols) 300IU 1000%
    Thiamin(as Mononitrate) 76mg 5067%
    Riboflavin 76mg 4471%
    Niacin(as Niacinamide) 82mg 410%
    Vitamin B6(as Pyridoxine AKG, Pyridoxine HCl) 180mg 9000%
    Folic Acid 400mcg 100%
    Vitamin B12(as Methylcobalamin, Cyanocobalamin) 17mcg 283%
    Biotin 300mcg 100%
    Pantothenic Acid 76mg 760%
    Calcium 2g 200%
    Phosphorus 1330mg 133%
    Iodine(from Kelp) 150mcg 100%
    Magnesium(as Oxide) 400mg 100%
    Zinc(as Oxide) 30mg 200%
    Selenium(as Sodium Selenate) 50mcg 71%
    Copper(as Sulfate) 600mcg 30%
    Manganese(as Sulfate) 5mg 250%
    Chromium(as Chloride) 60mcg 50%
    Potassium(as Sulfate) 200mg 6%
    Amino Acid Complex
    Alanine 339mg **
    Arginine 1326mg **
    Aspartic Acid 503mg **
    Cystine 104mg **
    Glutamic Acid 752mg **
    Glutamine 123mg **
    Glycine 287mg **
    Histidine 93mg **
    Isoleucine (BCAA/EAA) 282mg **
    Leucine (BCAA/EAA) 514mg **
    Lysine (EAA) 417mg **
    Methionine (EAA) 157mg **
    Phenylalanine (EAA) 232mg **
    Proline 143mg **
    Serine 285mg **
    Threonine (EAA) 266mg **
    Tryptophan (EAA) 84mg **
    Tyrosine 192mg **
    Valine (BCAA/EAA) 314mg **
    Performance Complex
    Argentine Liver (Bovine) 3900mg **
    Carnitine 25mg **
    Choline Bitartrate 950mg **
    Eleuthero (Root) 1750mg **
    Hawthorn (Berry) 250mg **
    Milk Thistle 500mg **
    Oriental Ginseng (Root) 250mg **
    Para-Aminobenzoic Acid 400mg **
    Pyridoxine A-Ketoglutarate 200mg **
    Antioxidant Complex
    Alpha Lipoic Acid (ALA) 100mg **
    Citrus Bioflavonoids 1000mg **
    Coenzyme Q10 (CoQ10) 5mg **
    Grapeseed Extract 50mg **
    Lutein 1mg **
    Lycopene 1mg **
    Pine Bark Extract 200mg **
    Digestive Enzyme Complex
    Bromelain 100mg **
    Inulin 250mg **
    Lipase (6000 LU) 10mg **
    Pancreatin 700mg **
    Papain 64mg **
    Pepsin 64mg **
    * Percent Daily Values are based on a 2,000 calorie diet.
    ** Daily Value (DV) not established.
    Other Ingredients:
    Dicalcium Phosphate, Whey Protein Concentrate (Milk), Microcrystalline Cellulose, Glucose Polymers, Arginine A-Ketoglutarate, Stearic Acid, Magnesium Stearate, Calcium Carbonate, D-Calcium Pantothenate, Silicon Dioxide, Carnitine Fumarate, Calcium Citrate, Alfalfa, Rose Hips, Rice Bran, Parsley, Burdock.
    Made in a GMP facility that uses milk, soy, egg, peanut

  10. #10
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    Great Post!

    Great post and I agree, Vitamin C is a super vitamin way beyond all others, the more the better IMO and after the research Ive done, Ive stuck with it and take 5-10gs daily.

    Oh I also always take 2 animal paks, 1 in the morning and one before training and can I just say, its actually TWO packs that give 1g of Vit C, not just ONE pack. I fell for that to start with until I read that serving size = 2 packs!

    Thanks for the post

  11. #11
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    I love animal paks.

  12. #12
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    So mega dosing can slow down muscle recovery? I've been taking about 1g a day for awhile been thinking about mega dosing this stuff. Is the powder the best form to buy?

  13. #13
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    baseline_9 is offline The Transformer ~VET~Recognized Staff Winner - $100
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    Nice one Swifto... I need to start bookmarking some of your threads...
    Don't be a 'Bro'..... Believe nothing....Question everything

    Baseline - Working to phase out this generation of Bro-Scientists

    Stop over thinking nutrition - If you want something to think about download Myfitnesspal and learn how to count macros




  14. #14
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    Quote Originally Posted by baseline_9 View Post
    Nice one Swifto... I need to start bookmarking some of your threads...
    Indeed, swifto has to be the coolest mofo in the world of bodybuilding... Now if he could only answer my question...

  15. #15
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    Quote Originally Posted by dukkitdalaw View Post
    im a firm believer in mega dosing vit c for many reasons/purposes. i take 8-12g of vit c a day. and swear by it. ive gotten many friends to do so and they also swear by it.

    its affects on immune system, energy, cortisol, joint pain etc have all been studied and shown to be affective.

    there a few good threads out there about mega dosing vit c.

    so yes... i def agree with this post. nice one marcus
    Along this train of thought, if you're interested in "high dose" vitamin c, I'd also suggest delving into liposomal vitamin c...it will, 1) prevent the potential gastric distress associated with high dose vit c and 2) dramatically increase bio-availability. The research presented for its benefits is quite compelling. I'd post some links, but due to my "Post Count," this isn't an option at this time.

    OOS

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