And you guys have a chance to win a free bottle http://forums.steroid.com/showthread...92#post6248892
Yours,
ar-r
And you guys have a chance to win a free bottle http://forums.steroid.com/showthread...92#post6248892
Yours,
ar-r
Here are my three:
1) Cardio Caps
2) Slim Gyms
3) EnduroMax (EnduraMax)
Let's do it!Quote:
Originally Posted by ar-r
GW-1516 (GW) is a compound known as a peroxisome proliferator-activated receptor (PPAR) modulator. PPARs mediate many biological processes and are being researched for their actions in the involved in the development of some known chronic diseases such as diabetes, atherosclerosis and obesity.
GW is an effective modulator of PPAR’s actions and has been found to be a key metabolic regulator showing many positive actions in tissues and processes such as lipid oxidisation and skeletal muscle.
A major finding with GW is its effects in preventing the down-regulation of AMPK caused by high-fat diets in the liver and has been found to amplify the PGC-1a-Lipin 1-PPAR pathway leading to increased fatty acid oxidation and enhanced fat-loss. This seems to be one of the most notable effects of GW and it goes hand in hand with providing cardiovascular protection in research subjects with obesity issues.
GW has been shown to have muscular protective and enhancing effects as well. GW has shown to decrease muscle inflammation and muscle damage in research subjects along with showing an increased gain in body and muscle weight in all treated research subjects administered GW.
Refs:
1) PPARδ Activation Protects Endothelial Function in Diabetic Mice.Tian XY, Wong WT, Wang N, Lu Y, San Cheang W, Liu J, Liu L, Liu Y, Lee SS, Chen ZY, Cooke JP, Yao X, Huang Y. http://www.ncbi.nlm.nih.gov/pubmed/22933110
2) Role of peroxisome proliferator-activated receptor beta/delta in chicken adipogenesis.Sato K, Yonemura T, Ishii H, Toyomizu M, Kamada T, Akiba Y. http://www.ncbi.nlm.nih.gov/pubmed/19619666
3) Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model.Jahnke VE, Van Der Meulen JH, Johnston HK, Ghimbovschi S, Partridge T, Hoffman EP, Nagaraju K. http://www.ncbi.nlm.nih.gov/pubmed/22908954
4) Lipid effects of peroxisome proliferator-activated receptor-δ agonist GW501516 in subjects with low high-density lipoprotein cholesterol: characteristics of metabolic syndrome.Olson EJ, Pearce GL, Jones NP, Sprecher DL. http://www.ncbi.nlm.nih.gov/pubmed/22814748
5) The PPARβ/δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1α-Lipin 1-PPARα pathway leading to increased fatty acid oxidation.Barroso E, Rodríguez-Calvo R, Serrano-Marco L, Astudillo AM, Balsinde J, Palomer X, Vázquez-Carrera M. http://www.ncbi.nlm.nih.gov/pubmed/21363937
It is coming!Quote:
Originally Posted by ar-r
Soon.....very soon!