Max. Weekly Weight Loss on Clen/EC stack?

[boisebeast]

General rule of thumb I come across all the time is not to lose more than 2 lbs a week on a cut (natty), but what numbers should I shoot for per week if I'm on Clen or an ECA stack?

Side question: any major disadvantages to excluding aspirin from an ECA stack and just doing something like 40mg ephedrine and 200mg caffeine twice a day?

[boisebeast]

Bump, anyone?

[hearnrumors]

To answer your side question:

"Aspirin is included in the ECA stack to help prolong the effects of ephedrine. Basically as a normalizing procedure the body reacts to ephedrine by producing prostaglandins and adenosine outside the cell, and phosphodiesterase inside the cell. Inside the cell, it has been found that methylxanthines, like caffeine, inhibit the activities of phosphodiesterase. Stimulation of the beta receptors by ephedrine (via noradrenaline) causes an increase of cAMP (cyclic adenosine monophosphate) within the cell. This crucial part of the process that leads to thermogenesis is vulnerable because cAMP is degraded by phosphodiesterase. Outside the cell, aspirin inhibits the peripheral synthesis of prostaglandins. Prostaglandins inhibit the release of noradrenaline in the synaptic junction (before receptor stimulation). So in other words without aspirin (and caffeine), the beta agonistic qualities of ephedrine (via noradrenaline) are practically negated by prostaglandins. Thermogenesis is prolonged because aspirin interferes with this negative feedback mechanism! " - Ironmag.com

[hearnrumors]

On JUST an eca stack, I personally have never been able to lose more than 2lbs/wk without noticing significant muscle loss. YMMV