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Thread: Ebola & estradiol

  1. #1
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    Ebola & estradiol

    Estradiol

    A hormone and steroid produced by woman, estradiol was found to exhibit anti-Ebola virus activity in vitro, indicating the relevance of hormonal factors and perhaps gender in susceptibility to the disease.

    A 2013 analysis entitled, “A systematic screen of FDA-approved drugs for inhibitors of biological threat agents,” detailed the findings:

    “We also identified estradiol and toremifene, two steroidal hormones, as inhibitory to both MARV and EBOV. Interestingly, these compounds have previously been identified as inhibitors of New World arenaviruses but were suggested to interfere with late stages of viral replication and assembly.”

    Another study reported:

    “Anti-EBOV activity was confirmed for both of these SERMs in an in vivo mouse infection model. This anti-EBOV activity occurred even in the absence of detectable estrogen receptor expression, and both SERMs inhibited virus entry after internalization, suggesting that clomiphene and toremifene are not working through classical pathways associated with the estrogen receptor.”

    Source Link
    http://consciouslifenews.com/theyre-...ebola/1177324/

  2. #2
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    Maybe it's time to dose up and then go test this theory?

    Start a log.

    Day one.
    Started an estradiol cycle

    Day two.
    Exposed myself to Ebola

    Day three.
    adsfl asd asdfg

    Day four....
    aaaaaarghhhhh!

  3. #3
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    ROLMFAO!!!! Looks like SERMs show anti EBOV activity too. So we can just go on and extended PCT when there is an outbreak.
    Last edited by gold43; 10-15-2014 at 08:28 AM.

  4. #4
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    Quote Originally Posted by gold43 View Post
    Estradiol

    A hormone and steroid produced by woman, estradiol was found to exhibit anti-Ebola virus activity in vitro, indicating the relevance of hormonal factors and perhaps gender in susceptibility to the disease.

    A 2013 analysis entitled, "A systematic screen of FDA-approved drugs for inhibitors of biological threat agents," detailed the findings:

    "We also identified estradiol and toremifene, two steroidal hormones, as inhibitory to both MARV and EBOV. Interestingly, these compounds have previously been identified as inhibitors of New World arenaviruses but were suggested to interfere with late stages of viral replication and assembly."

    Another study reported:

    "Anti-EBOV activity was confirmed for both of these SERMs in an in vivo mouse infection model. This anti-EBOV activity occurred even in the absence of detectable estrogen receptor expression, and both SERMs inhibited virus entry after internalization, suggesting that clomiphene and toremifene are not working through classical pathways associated with the estrogen receptor."

    Source Link
    http://consciouslifenews.com/theyre-...ebola/1177324/
    Im a little confused. Are they saying clomiphene and toremifene work or dont because they are different from other AIs?

  5. #5
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    Anti EBOV activity was confirmed for both SERMS.

  6. #6
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    i really may choose Ebola over extending any PCT

  7. #7
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    GirlyGymRat is offline Knowledgeable Elite ~ Respected Female Leader ~
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    Quote Originally Posted by Times Roman
    Maybe it's time to dose up and then go test this theory? Start a log. Day one. Started an estradiol cycle Day two. Exposed myself to Ebola Day three. adsfl asd asdfg Day four.... aaaaaarghhhhh!
    Lmao

  8. #8
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