Starting Nebido.

[Flier]

Hi guys.
About to start Nebido.
On here now trying to find other members experience with injection frequency. And Nebido experience do´s and don´ts in general.
In Nebido threads many mention increasing frequency, but with what? The whole 4mg?
I am considering starting off with a 4mg per 10 week schedule. However due to the numerous complaints of low T symptoms towards the end of 10 weeks, I will be scheduling 2mg every 5 weeks instead of 4mg every 10 weeks. Thoughts?
Yes, I know, it is a 1 shot vial, but I was planning on filling 2 syringes with 2 mg each, and storing the second for 5 weeks. Is this ok?
In addition I am planning HCG 250iu E2D.
Hopefully I will not be needing an AI.

My endo wanted to put me on TRT due to my numerous low T symptoms, although my Total T has been a fluctuating 350-450 (I think the scale is like 280-1200), with correspondent equal scale values on Free T and E.
I have hesitated for 2 years because I don´t think my T is that low, but I guess it is time.

[marcus300]

every 11 weeks for me on my protocol, feel like 21yrs old, don't need an AI and feel amazing. 4ml 1000mgs every 11 week. I did start off on 12 weeker but dropped it to 11 weeks. 10 would be ideal but going with my endo recommendation at the moment, I would split the dose either, thats the beauty of this product let it build up and go with the less injections....

[kelkel]

There are several threads here on Nebido and members experiences with it. One is pretty current with a member starting recently. Search them up.
With frequency they're probably referring to weeks between injections once stable. Normally you would have your initial injection, then a booster approximately 6 weeks later. Then your injections frequency would be based on BW. I would not alter your program at this point. Let BW be your guide.

Post up how it goes on this thread please.


**there ya are. Was hoping you'd chime in Marcus.

[Flier]

Thanks Marcus and Kelkel.
Marcus, I just read your thread on Nebido. And I will be going through the links now.
See you are on 11 weeks, but you think 10 would be your sweet spot.
I got a great Endo who will let me choose my own TRT. (Not because he is reckless but he know I do a lot of research, and has known me for years). Additionally, in South America Nebido can be bought over the counter at Pharmacies.
So I am starting at 10 weeks, just because that is where it seems people "drop off", including Marcus.
However, since I am also doing 250 HCG E2D, I will be watching my levels so I they don´t go too high.
But why do you both say not to split the dose? When that is what you and others advocate with other esters. Like Cyp split into 2 times per week. Even though Cyp once per week would be within the half life of Cyp.
Every 10-12 weeks Nebido on the other hand would be on the other side of half life of this ester.
Kelkel, yes agree that is what they mean by frequency. But if they report a problem with "drop off" after 10-11 weeks, why not split the dose in 2?

[marcus300]

There's been that many studies on nebido going on for 8-9yrs and some go up against test e and the results show your better with the one shot and let the blood values build up that's the whole thing about it but for some it does take some time. I kind of noticed a slight drop at week 10 so he dropped my protocol to 11 weeks and he will check bloods and go from there but ive already told him I am fine at 11 weeks but I would go to 10 weeker it seems to be the right spot for many people once you get the blood levels up and running

[Flier]

Thanks!, well then I guess I will drop the other thinking of splitting doses due to the roller coaster effect caused by other esters.
Taking your advise I will shoot 4mg, then another 4mg 5 weeks later, then every 10 weeks thereafter.
Think I will shoot on Sundays, and I will take the plunge in a week or 2.
Do bloodwork in a couple of months, and adjust the dosage accordingly.
I will let you know my progress.

There is lots of info out there on HCG frequency and dosage. But no trials proving a "correct" dosage for maintaing testicular function.
Like I wrote, planning on 250iu E2D.
Any personal experiences?

[Back In Black]

I'm at the high end of mid range (19 on a scale of 9-25) after 10 and a bit weeks (after 10 months of treatment) so I'm ok on 11-12 week frequency.

[Flier]

Cool.
Not that I am set on 10 weeks. It just looks like many talk about a drop off after 10 weeks.
I could of course start with a 12 week schedule and adjust from there.
Nomatter what, I will shoot 4mg, and I will have a few weeks to make the decision to load at 5 weeks or 6.
Many scales out there. My EU scale is 8-35. On it I am sitting around 10-12. My aim on Nebido will be mid twenties.
How has your experience on Nebido been?

[Back In Black]

It's been great. One shot every 3 months to feel 'normal' again. No AI. I shoot 250iu's HCG x 2 per week to keep my nuts in order.

I feel extra horny a week after my shot but other than that I feel like I used to when I was younger.

Had my booster after 6 weeks you should get bloodwork 12 weeks after IMO. 10 weeks after my booster I was at the top of the scale.

[wmaousley]

I pin every 11.5-12.5 weeks. Not really sure why this varies but it does. I see my doctor every other month so he can monitor my test levels. (It seems he is doing his own research).

I feel great and better than ever. I recommend you work closely with a physician during the first year so he/she can fine tune your administration schedule.

What I have found is I am more sensitive to other test esthers and notice them faster than if I weren't taking Nebido. SO be careful if you are going to cycle on top of taking Nebido, however I strongly recommend you don't cycle until you have been taking Nebido for at least a year.

[Lifted1]

are you guys injecting nebido yourselves? one shot every 10 weeks sounds nice...shit that's like your not even on trt lol

[Back In Black]

are you guys injecting nebido yourselves? one shot every 10 weeks sounds nice...shit that's like your not even on trt lol

Marcus does his own. The nurse at my GP does mine, means I don't have to pay for it

[kelkel]

I pin every 11.5-12.5 weeks. Not really sure why this varies but it does. I see my doctor every other month so he can monitor my test levels. (It seems he is doing his own research).

WM I would absolutely love to see you chart out your pre-TRT and every other month progression when it comes to TT and FT levels as well as E2 if possible. I think it would be very beneficial to the guys here as a learning tool.

[Flier]

Wmauousley, and you don´t have any low T symptoms at week 10 others report?
Never say never, but I don´t think I will be cycling ever again. Never really did. However experimented with Prop and Cyp couple of years ago to try to figure out if my low T symptoms actually came from lowT.
While experimenting I never found the T "high" or wellness feeling other report. If anything I felt worse, like internal stress, and the feeling of my body fighting a foreign substance.
Although nocturnal erections improved with higher T, my conscious erections got worse. I believe bc of the "stress" I am referring to.
I hope my experience with Nebido will be different.
WM…HCG?

Lifted, I will be pinning myself as I am rarely in the doc´s office. Can choose from 21G - 27G.
What do you Nebido guys use? I have been handed the 21g, but hinting of switching it out for something more pleasant.

[Back In Black]

My nurse uses 21g. It's a really thick liquid, you'll be pinning for a minute or more anyway as per instructions.

[clarky.]

My nurse uses 21g. It's a really thick liquid, you'll be pinning for a minute or more anyway as per instructions.

X2 on this ^^ one and a half to two min it's a very thick oil.

I get mine every 10wks just now as well but i feel it on the 8th wk so got bloods done last wk to see where i am i might have it reduced to every 8-9 wk mark.

[yettibecsuse]

I do my own injection and my endo gave me three repeats said see u in 36 weeks my levels are that stable I test them check them they stay consistently the same for 10 weeks then slight drop which I don't fret about its really that easy

[marcus300]

I inject myself my doctor is fine with this after I told him my history.

[wmaousley]

are you guys injecting nebido yourselves? one shot every 10 weeks sounds nice...shit that's like your not even on trt lol

I inject myself, only because 4ml of Oil injected into one place seems to feel like I was kicked by a horse for a couple days, so I divide the injection into two and pin different places.

[wmaousley]

WM I would absolutely love to see you chart out your pre-TRT and every other month progression when it comes to TT and FT levels as well as E2 if possible. I think it would be very beneficial to the guys here as a learning tool.

The next time I see my doctor I will ask for a progress report and chart it for you guys.

[wmaousley]

Wmauousley, and you don´t have any low T symptoms at week 10 others report? No I actually only felt symptoms during the first 2 administration cycles. After that I have felt 100% great.
Never say never, but I don´t think I will be cycling ever again. Never really did. However experimented with Prop and Cyp couple of years ago to try to figure out if my low T symptoms actually came from lowT.
While experimenting I never found the T "high" or wellness feeling other report. If anything I felt worse, like internal stress, and the feeling of my body fighting a foreign substance.
Although nocturnal erections improved with higher T, my conscious erections got worse. I believe bc of the "stress" I am referring to.
I hope my experience with Nebido will be different.
WM…HCG? No, and actually my doctor said its not necessary, and it may confuse my body.

Lifted, I will be pinning myself as I am rarely in the doc´s office. Can choose from 21G - 27G.
What do you Nebido guys use? I have been handed the 21g, but hinting of switching it out for something more pleasant. Try to use a large enough pin that is comfortable as the oil is super thick for some reason.

See answers in red.

[kelkel]

WM you need to educate your doc about hcg. It won't confuse your body, only replace what it's missing.

[Flier]

I inject myself, only because 4ml of Oil injected into one place seems to feel like I was kicked by a horse for a couple days, so I divide the injection into two and pin different places.

Funny statement from my endo….."Some guys screw up and actually split the dose in 2 and inject into 2 separate spots. Which reduces the effective duration of the medication in half. Ie only 6 weeks instead of 12"…..
Scary, right?

Re HCG. Probably all trials with Nebido has been done without HCG, so I see how we can in one sense be in uncharted territory, with T and E slightly higher than the Nebido test subjects.
However many TRT´ers have reported an enhanced wellbeing after adding HCG.
Personally I will be adding HCG for family planning.

[wmaousley]

Funny statement from my endo….."Some guys screw up and actually split the dose in 2 and inject into 2 separate spots. Which reduces the effective duration of the medication in half. Ie only 6 weeks instead of 12"…..
Scary, right?

Re HCG. Probably all trials with Nebido has been done without HCG, so I see how we can in one sense be in uncharted territory, with T and E slightly higher than the Nebido test subjects.
However many TRT´ers have reported an enhanced wellbeing after adding HCG.
Personally I will be adding HCG for family planning.

He could be right, he could be wrong. Maybe this is dependent on the individual. I have never heard this statement or read anything about it.

[wmaousley]

WM you need to educate your doc about hcg. It won't confuse your body, only replace what it's missing.

Im def going to mention it on my next visit.

[Back In Black]

He could be right, he could be wrong. Maybe this is dependent on the individual. I have never heard this statement or read anything about it.

It's easily found if you look not very hard. The reason for the slow release is the size of the globule and thickness of the oil. Bloodwork is king though!

[Flier]

It's easily found if you look not very hard. The reason for the slow release is the size of the globule and thickness of the oil. Bloodwork is king though!

Seriously?
I was actually making joke of my Endo´s statement, but maybe the joke is on me…?

So, then this would apply to all esters. Splitting the Cyp dose in 2 actually cuts back on Cyp half life?
If you are right, it becomes very important to keep the needle completely still while injecting, to actually create this "globule".

[kelkel]

Im def going to mention it on my next visit.

Search up Crisler or Vergel's papers on it and take it to your doc.

[wmaousley]

It's easily found if you look not very hard. The reason for the slow release is the size of the globule and thickness of the oil. Bloodwork is king though!

Im good, no need for me to look this up. I'm busy researching in my career plus I pay doctors to do this for me. Splitting my dose hasn't harmed me in the least. If its not broke, don't fix it.

[Flier]

Crossed over to the dark side today, for a brighter future.
4ml of pure liquid Manliness into the right buttock.
After considering others experiences, and doing some thinking, I will be starting out on the 12 week protocol, with a 6 week booster.
I will adjust if I personally feel the 10 week drop-off some speak of. But not until completing 1 year of the 12 week protocol, allowing for the build-up mentioned in one of the studies posted by Marcus.
No AI, but HCG. For now, 250iu EOD, but will drop to as little as possible while maintaing size.
I´ll keep this thread updated with BW and progress.

[marcus300]

Crossed over to the dark side today, for a brighter future.
4ml of pure liquid Manliness into the right buttock.
After considering others experiences, and doing some thinking, I will be starting out on the 12 week protocol, with a 6 week booster.
I will adjust if I personally feel the 10 week drop-off some speak of. But not until completing 1 year of the 12 week protocol, allowing for the build-up mentioned in one of the studies posted by Marcus.
No AI, but HCG. For now, 250iu EOD, but will drop to as little as possible while maintaing size.
I´ll keep this thread updated with BW and progress.

Excellent sounds good to me

[BigPimpin76]

Dont mean to highjack this thread but does Nebido raise E2?

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[Flier]

Dont mean to highjack this thread but does Nebido raise E2?

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If E2 (Estrogen) is produced from Testosterone conversion, then any Testosterone will raise E2. (Cyp, Prop, Patches, gels, HCG, and Nebido)
However I have heard slow release esters such as Nebido will raise E2 less, due to less Testosterone spike.
From what I have read so far, the majority of Nebido users do not use AIs. And I will not use one.

[Flier]

Finding a "pile" of hair at the bottom of the shower for a couple of weeks.
(What I didn´t mention before is, I was on 120mg/week Cyp for 3 months before transitioning to Nebido)
My scalp is itching and the hair obviously falling off.
I have a full head of hair. And no genetic baldness in the family.
I have said for years I will not trade my hair for TRT, but I will make no hasty decisions.
My experience from the last 4 years of experimenting with TRT, cycles etc is that I do find hair in the shower, but once I stop the compound the hairloss stops and whatever lost grows back. So I am not worried.
I will definitely press on. I will also next week be reducing my HCG from 250iu E2D to 250iu 2/week.
I will be getting BW early January, including DHT.
Besides that, I feel great. Number 1 for me so far, is the "brain fog" is gone.

[FakeLove]

Great to hear that it works. I'm sure the BW will support your feelings. You gonna measure E2 as well in January?

I just got my second Nebido jab yesterday 6 weeks after the first one. The third jab will be in 8 weeks and we're going to see the peak and trough values before it and then adjust the injection protocol based on the trough.

Feels good for me too. If you're interested, three weeks after my first jab the labs showed:

TT 30 nmol/l (10-38)
Free T 589 pmol/l (200-500)
SHBG 17 nmol/l (10-57)
E2 0,16 nmol/l (<0,15), Anastrozole 0,25mg E3D.

[Flier]

Ok..
So got BW on Jan 9.
That is 5 days after my 5 week "booster shot"
So I am not too worried about the off numbers. They will obviously settle once I wait 10 weeks for the next.
But the "brain fog" came back. Along with reduced vision. Both I guess can be related to high Glucose and/or E2?
Here are some of the numbers:

TT: 1029 (280-1100)
E2: 88 (7.6-42.6) ….wow!
Free T: 27 (2-27)
SHBG: 27 (10-80)

IGF1: 295 (119-166) …from 300 mcg Sermorilin ED.

TSH: 1.9 (0.3-4.2)
T4: 1.5 (0.9-1.7)
T3: 2.8 (1.8-4.6)

Glucose: 106 (65-100) …don´t like.

In addition to Nebido, I am taking 250iu HCG 2/week.
Because of the high E2, I am now also starting 0.5 mg Adex 2/week.

Any thoughts, comments, suggestions, questions?

[ppwc1985]

I wouldn't start out the adex at .5, drop it to .25 twice a week to start. Then get you more bloods in 6 weeks. My levels were similar and I dropped to within range.

[OingoBoingo]

That's a lot of Anastrozole.

Do you have any high E2 symptoms;such as, flushing around the upper chest and neck, or night sweats? If so, it might be better for you to take Anastrozole when needed instead of putting yourself on a schedule.

Everybody is different, but I crushed my E2 on 0.25mg Anastrozole every 4 days.

[Flier]

Shit, seriously..
There are so many different experiences re Anastrozole.
But I¨ll take ur advise and do .25/2 x week.
I just have to open the capsule, and measure half the powder.
Thanks.

[kelkel]

Overall great numbers, E2 aside....