You will get different opinions on this, some will say Tamox others say letro. Basically you will have to experiment with this everyone reacts differently to medication. Try using the letro first at .25mg - .50mg per day.(Letro helps reduce that bloat look that you might get from some AS) If you notice no discomfort around the nipples then I would not bother with tamox until PCT. If you do, add some tamox to it 25 mg at first and increase it gradually until no more discomfort. But remember to discontinue the use of the letro before PCT.