HELP!! diuretic experts::hydrochlorothiazide

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Right now I'm researching the use of Plasma Expanders (long chain starches like Mannitol, etc...) and some other pretty cool compounds (IV albumin) for use as a diuretic in BB'ing comps....I'm a long way from refining it, though...to my knowledge, Duchaine knew about the use of Mannitol, but nobody's ever used it, and I don't think anyone's ever even speculated on IV Albumin for such a use.

I'm on it...but...I don't think you can get any of this stuff on the fly...also...some of them are necrotic (not albumin, but alot of the others)....meaning, if you shoot it IV, and miss the vein....you have to bleed out your arm, 'cuz it'll start killing muscle.

Dangerous? Hell yeah.

Cutting edge? Hell yeah!

[j martini]

Right now I'm researching the use of Plasma Expanders (long chain starches like Mannitol, etc...) and some other pretty cool compounds (IV albumin) for use as a diuretic in BB'ing comps....I'm a long way from refining it, though...to my knowledge, Duchaine knew about the use of Mannitol, but nobody's ever used it, and I don't think anyone's ever even speculated on IV Albumin for such a use.


I'm on it...but...I don't think you can get any of this stuff on the fly...also...some of them are necrotic (not albumin, but alot of the others)....meaning, if you shoot it IV, and miss the vein....you have to bleed out your arm, 'cuz it'll start killing muscle.

Dangerous? Hell yeah.

Cutting edge? Hell yeah!

I know chad nicholls thought about the use of plasma expanders pre contest apparantley he came to the conclusion that they would not work.

[j martini]

Here is the reasons he gave

Administering a plasma expander is quite a task. You need more than one person to do it and it isnt for the squeamish.
The plasma expander must be intravenous through an IV drip. For an athlete the dosages would vary between 500ml-1000ml, with a maximum dosage of 1500ml per day.
The breakdown with respect to how much fluid an athlete can pull would vary depending on their fluid situation and body type.
But, as an example, for approximately every 500ml of dextran or heta starch administered, 150-200ml of fluid can can be drawn from extra vascular tissue into the bloodstream in 30-40mins. This sounds great right?
Unfortunately these numbers are based on the average person who is hydrated. When you put this into a bodybuilding equation, you arent getting as succesful a withdrawal rate.
A couple of days before a show a bodybuilder is restricting their fluid intake, so the amount of fluid that could be pulled would be cut in half, if even that much.
On average a bodybuilder could only pull 75-100ml of fluid for every 100ml of dextran or heta starch administered. Not much when you think off what you have to go through to pull that small amount of fluid.
When you arent supposed to exceed 1500ml a day and youre only able to pull about 300ml of fluid, it just doesnt make much sense.
Lets say you have the perfect scenario, however. You are able to pull the maximum amount of fluid for an average person in a days time - 600ml. Youre still pushing the boundaries , having to take high amounts of these substances to do this. You would have to take 1500ml during that day - the absolute limit for a day and in my opinion, a very dangerous level for such a small amount of fluid withdrawn.
If you have still decided to go through with this, what are you going to do with the fluid once you have pulled it? Did you know that you only have a window of about an hour or less to get rid of all the water you have just pulled, before all of it and more spills back into your system? so, up until this point, everyone bhad been thinking that due to the fluid pulling effect of the plasma expander, it could be used as a diuretic and thus, a new way to get around a diuretic test. What people failed to figure , however, is that with only an hour window, how are they going to get rid of this fluid so it wont be re-deposited back into the system? Well, you have to use a loop diuretic. Wait a minute! arent loop diuretics banned substances? Yes they are. This is what i tried to convey - the reasons why i didnt use them and they wouldnt work but no one would listen.
In the medical field, when administering thes substances(for example, Manitol)
doctors use what they call a cocktail, which wouild include not only the manitol, but usually a loop diuretic.
This same theory would have to be used in bodybuilding and thats why plasma expanders and osmotic diuretics dont work.