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  1. #1
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    I am beginning to think HCG is worthless. We all know it doesn't upregulate the HPTA it further suppresses it. It may desesitize the testicles and it rapidly converts to estrogen in the body at any dosage. I don't know what I should expect but I haven't noticed any effects from taking it. Perhaps a surge in test lasting one day, but that is ultimately of no use to me.

  2. #2
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    Quote Originally Posted by powerliftmike
    I am beginning to think HCG is worthless. We all know it doesn't upregulate the HPTA it further suppresses it. It may desesitize the testicles and it rapidly converts to estrogen in the body at any dosage. I don't know what I should expect but I haven't noticed any effects from taking it. Perhaps a surge in test lasting one day, but that is ultimately of no use to me.
    What do you bros think?

  3. #3
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    Quote Originally Posted by powerliftmike
    I am beginning to think HCG is worthless. We all know it doesn't upregulate the HPTA it further suppresses it. It may desesitize the testicles and it rapidly converts to estrogen in the body at any dosage. I don't know what I should expect but I haven't noticed any effects from taking it. Perhaps a surge in test lasting one day, but that is ultimately of no use to me.
    I think this should help, I have always thought of HCG as just another way to get the testes back to size and more active to begin PCT effectively. This is why I advocate it's use at the end of a cycle.

    Quote Originally Posted by JohhnyB(Nandi12)
    Tamoxifen Blocks HCG Induced Leydig Cell Desensitization
    HCG induced testicular desensitization seems to be a hot topic. There are a number of studies showing that concomitant use of Nolvadex ameliorates this. The first abstract suggests that HCG at least partially blocks the conversion of 17 alpha-hydroxyprogesterone (17 OHP), a testosterone precursor, to testosterone. This effect is suppressed by Nolvadex.
    So if you can increase testicular function without desensitizing the teste receptors then you have made a jump start on PCT enhancing the ability of agents like clomid/nolva/a-dex to stimulate the HTPA.
    Last edited by shortie; 10-18-2005 at 02:07 PM.

  4. #4
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    Quote Originally Posted by shortie
    So if you can increase testicular function without desensitizing the teste receptors then you have made a jump start on PCT enhancing the ability of agents like clomid/nolva/a-dex to stimulate the HTPA.
    That's the point exactly

    JohnnyB

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