A question for the Vets (or those up to the discussion)

[daem]

Nark - I've read that increased Leptin levels are often accompanied by an increase in luteinizing hormone and greater activation of the LH receptors.

Since HCG can supposedly cause gyno, as it stimulates LH, I would venture that Leptin indirectly influences other physiological responses that can trigger gynecomastia.

By itself, does it cause gyne? I don't think so.

[LATS60]

Nark - I've read that increased Leptin levels are often accompanied by an increase in luteinizing hormone and greater activation of the LH receptors.

Since HCG can supposedly cause gyno, as it stimulates LH, I would venture that Leptin indirectly influences other physiological responses that can trigger gynecomastia.

By itself, does it cause gyne? I don't think so.

I was interested in the leptin thing, but can you explain how HCG stimulates LH, i thought it mimicked LH and was more likely to suppress production of our own LH from the pituitary while taking it, isn't that why it should be stopped before PCT so that we can start producing our own LH again.
HCG can be a contibutory factor to gyno but isn't that only by it's secondary action of increasing test which then in turn leads to more aromatisation.

[daem]

I was interested in the leptin thing, but can you explain how HCG stimulates LH, i thought it mimicked LH and was more likely to suppress production of our own LH from the pituitary while taking it, isn't that why it should be stopped before PCT so that we can start producing our own LH again.
HCG can be a contibutory factor to gyno but isn't that only by it's secondary action of increasing test which then in turn leads to more aromatisation.

HCG is an LH substitute since it activates the same receptor, but from my rudimentary knowledge, this activation in turn leads to increased LH in the body after administration has ceased...I don't think it is a one and done deal.

I'm pretty sure you are correct that it suppresses natural levels, but upon cessation, the pituitary is basically recalibrated, the testes start functioning again, and LH production begins.

I'm no expert nor claim to be...I was just throwing some other possibilities out there

[Narkissos]

Nark - I've read that increased Leptin levels are often accompanied by an increase in luteinizing hormone and greater activation of the LH receptors.

Since HCG can supposedly cause gyno, as it stimulates LH, I would venture that Leptin indirectly influences other physiological responses that can trigger gynecomastia.

By itself, does it cause gyne? I don't think so.

The same can be said about alcohol (and a number of other compounds)... re: not causing gyno by itself... rather contributing to a chain of events which lead to gyno.

Honestly I think, in attempting to treat gyno, people only look at the end.

i.e. "Elevated estrogen... Oh dear, time for letro!"

-CNS