
Originally Posted by
GearHeaded
I'm not doubting your experience in any way there Sil . and I know exactly what you mean in regards to blood work (like you, I don't waste my money getting e2 levels checked these days, I know exactly how 5x normal E levels feel like, and I know exactly what 2 weeks worth of Letro will do).
I've personally never used DIM before for estrogen control. However I'm aware of it and it was fairly popular in the early 2000s (along with Lycopene) . I'm sure your aware that there are many many forms of Estrogen in the body , and that Estrogen is a generic term that refers to all of them in general (kinda like the term "steroid" refers to the thousands of different steroids, and that there is not simply ONE 'steroid'). DIM is best known for decreasing 'bad estrogens'.
Di-indoly-methane (DIM), lndol-3- carbinol (1-3-C), lycopene, do have studies supporting their beneficial effects upon decreasing bad estrogens while increasing the good. DIM and 1-3-C both potentially aid in estrogen deactivation and evacuation. They do so by inhibiting the conversion enzyme responsible for 16a-Hydroxyestrone formation. This then forces the body to utilize the C-2 pathway and increase the production of 2a-Hydroxyestrone. The body then excretes the inactive metabolite of 2a-Hydroxyestrone rather quickly and effectively. This results in less total circulatory estrogens as well.
One of the 'gurus' that I followed for a long time (until he passed away a few years ago) , Author L. Rea , had used DIM with some of his athletes. However at the time I believe Author was unaware of new research that was coming out showing DIM to be an Androgen Antagonist and better utilized for prostate problems and blocking androgen receptors there then it was as an anti estrogen.
I'm not looking for a debate. I'm simply sharing some information with you that perhaps you may of been un aware of, and in the future said information could be of benefit to you and your progress.
but if something works for someone personally, then all the more power to them, keep doing what works