I’ve never had any issues at all with thyroid and have never used T3 so can’t speak to that either. You may be overthinking it a bit, but I recognize you’re doing your due diligence, so I get it. I was nervous the first time I used tren too. The only thing I wasn’t prepared for was the feeling hot all the time, the shortness of breath and the insomnia. What I know now that works for me. Is keeping my tren higher than my test, watching my carbs before bed, running cardarine (10-20 mgs a day), monitoring my cholesterol and liver enzymes, having ambien or a sleep aid on hand and not wearing wool sweaters.
I’ve done 4 tren runs and each has gotten better. My sweet spot is about 450 a week, more than that I’m a mess. I also went against the grain and ran enth the first time (and every time) and have run it on average 12 weeks. (I’d consider going 8 instead of 6 for your run, but that’s just me).
I also ran mast for the first time (at 400 a week) for the duration and felt great and really liked the aesthetics it added, it also helped my libido as well.
That’s all I can share man, everyone seems to have a different tren experience, at some point you just gotta dive the fuck in and see what happens.





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