
Originally Posted by
samoth
A new ADHD drug is being released in the US within the next month, Provigil (Modafinil), previously unavailable for ADHD. I'll be trying it within the next few weeks, as I've been looking to step down the amounts of heavy stim meds I'm taking. Provigil has no or minimal effect on dopamine-mediated wakefulness, locomotor activity, stereotypy, anxiety, blood pressure, heart rate and NREM rebound. Both methylphendiate, amphetamine, and their individual isomers effect all of the aforementioned.
Focalin, d-methylphendiate, might be another worthwhile drug with minimal PNS stimulation and minimal recreational potential, but I have yet to try this specific isomer, as I currently take Adderall XR. Amphetamine and methylphendiate don't mix well due to their known mechanisms counteracting each other in certain areas in the brain.
HTH