First injection was 4 nights ago. I read the dosing protocol on a melanotan discussion board and I dosed accordingly. I take my injections at night because I read that one might expeience some nausea and frequent erections and I thought it would be wise to use at night so I wasnt going thru my day with wood!. I did not get any nausea, but I did get a raging hard on an hour after injection. Next 3 doses went the same. After 4 days my skin already has more color. I will keep you posted.