CEE and Kre-alkalyn debunked?

[Drummerboy]

http://insidebodybuilding.blogspot.c...-debunked.html

I know that mono raises my strength and size quite well... i deal with the extra water and a little gurgly stomach... im unsure that the new creatines do anything more that mono... what do you say? read the artice..

~DB~

[Drummerboy]

http://www.npicenter.com/anm/templat...8806&zoneid=28

a repeat

[Jfew44]

Honestly I have very little gains on monohydrate. I've seen that many people are the same way. CEE brings my strength up a little more than mono, but I dont gain much weight from it. Its up to how different peoples bodies react IMO. I get way better gains from any Nitric Oxide product I've taken. If Creatine Mono helps you out by all means keep at it bro. You're lucky

[Drummerboy]

i have yet to try to NO products... but i am curious for sure...

[tjpatrick1987]

Okay i read the article and i am baffled at what all of this is suppose to mean so if someone can put this into Laymans terms that would be great

[Dog-Slime]

All they did was test how much is converted to creatinine in a liquid that SIMULATED stomach acid. This shows no correlation to how much creatine actually gets absorbed and to the muscles. Mono does NOTHING for me. CEE and CEEM do a little for me tho still not the super muscle builder that some make it out to be. Will be trying kre-alkalyn on my next purchase.

Real world experience > simulated lab experiments IMO.

[Drummerboy]

yea.... need a few more studies to back it up...

[tjpatrick1987]

i am on my 3rd day on 1.5grams kre-aklyn and i dont think it has given me strength or energy at all.... im gunna give it 30 days and if i dont notice a difference i am going to mono because im trying to make big gains plus im skinny

[abbot138]

I get pretty decent size/strength gains from stacking CEE, AAKG, and Beta-alanine. I just buy the bulk powders and make my own NO2 drink so I can control doses, much cheaper too. The Beta-alanine really helps with Creatine effectiveness, helps pump too. But I retain water regardless of if I use CEE or Mono. I dont notice a huge difference between the 2.

[goose]

what horse shit,people in the know that Kre-Alkalyn is the best,but CEE is poor,you got studies that prove that,here is a study:


Start Date: March 1st 2006th
Finished Date: April 30th, 2006

Dr. Kamen Stroychev & Neno Terziiski, Comparison of Kre-Alkalyn to Creatine on body composition, muscular performance, & safety: Dr. I.S. Greenberg Medical Center, Sofia, Bulgaria.

Objectives: The purpose of this study was to compare the effects of Kre-Alkalyn and Creatine Monohydrate on training induced changes in strength and body composition using Olympic-level weight lifters.

Methods: Using a random, double-blind design, 24 healthy men from the Bulgarian National Weight Lifting Team were selected and assigned to ingest 10 capsules x 750 mg of Kre-Alkalyn daily (for the test group) and 10 capsules x 750 mg of creatine monohydrate (for the controlled group). Verification of purity was assayed by an independent laboratory. Body weight was monitored, even though participating athletes were on strict diets due to their Olympic status of competition. Muscular performance was measured in the snatch, clean & jerk, high snatch, & back squat. Lifts were performed at maximum resistence for 1 repetition. The duration of the study was 60 days. Measurements were taken on baseline day and every day throughout the study per each athlete’s schedule. The best lift during the administration part of study was used for the comparison. Each athlete was required to maintain their normal dietary and training patterns during the study.

Results: The Creatine Monohydrate group showed an average increase over baseline of 8.39% for the snatch, clean & jerk, high snatch, & back squat. The Kre-Alkalyn group showed an average increase over baseline of 10.76%. By comparison, the average increase in total lifts for the Kre-Alkalyn group in the snatch, clean & jerk, high snatch, & back squat was 28.25% over the Creatine Monohydrate group.
Additionally, the Kre-Alkalyn group appeared to be healthy without any side effects from daily Kre-Alkalyn administration. No significant changes in body weight for either the Creatine Monohydrate group or the Kre-Alkalyn group were noted.

Conclusion: Within the framework and context of the current experimental design, this study concluded that subjects in the Kre-Alkalyn group increased their weight poundages by an average of 28.25% over subjects in the Creatine Monohydrate group. It should be noted that it is quite difficult for high-caliber Olympic-level athletes to produce considerable improvements in their muscular performance in such a short time-frame. Therefore, a 28.25% increase is considered to be a significant value


Effects Of Creatine Supplementation On Cellular Protein Metabolism In Vitro
“Kre-Alkalyn -vs- Creatine Monohydrate”


January 31st, 2008
Dr. Kamen Stroychev, MD (Greenberg Medical Center, Sofia, Bulgaria)


Objectives: The anabolic properties of creatine supplementation are well established, and we sought to determine the effects the stabilization process (used to manufacture Kre-Alkalyn) might have upon these metabolic effects.

Methods: To address this issue, established monolayer cultures of muscle cells (RD) or chondrocytes (SW1353) were subcultured in a deficient medium containing only 2.5 % fetal calf serum, instead of 10% which is mandatory for the optimal cell growth and maintenance in vitro. Thereafter, cells were exposed to either culture medium (controls) or 0.5 mmol conventional creatine (Creatine Monohydrate) or buffered creatine (Kre-Alkalyn). At different exposure periods (12, 24 or 48 h), the cells were detached from the cell culture flasks via trypsinization, washed thrice in PBS to remove residual protein from the culture medium and counted. Thereafter, the protein content in each sample was determined using the method of Lowry. The results were calculated as mg protein/106 cells and expressed as percentage of the untreated control (set as 100 %).

Results: Evident from the results obtained, both creatine formulations (conventional creatine and stabilized Kre-Alkayn) caused a significant time dependent increase in the protein content of either muscle or cartilage cells. In all experiments, however, the Kre-Alkalyn formulation caused a more pronounced augmentation of the protein anabolism, as compared to the non-stabilized counterpart (Creatine Monohydrate) (Table 4.1.; Figure 4.1.).



Appendix 4.
Experimental data for the effects of creatine supplementation on cellular metabolism.

Table 4.1. Effects of creatine supplementation on the protein synthesis of human muscle or cartilage cells cultured in FCS-deficient medium.
Exposure period (h) Protein content (% of untr. control)
Conventional creatine Kre-Alkalyn
RD muscle cells
12 109* ± 4 111* ± 1
24 112* ± 3 121*# ± 4
48 117* ± 2 124*# ± 2
SW1353 cartilage cells
12 105* ± 4 110*# ± 3
24 111* ± 4 117*# ± 3
48 115* ± 3 122*# ± 4
* Statistically significant (p<0.05) vs. the untreated control; # Statistically significant (p<0.05) vs. the equivalent concentration of conventional creatine (Student’s t-test).



Figure 4.1. Effects of creatine – conventional (white columns) or stabilized Kre-Alkalyn (grey columns) on the protein content in cells (upper plot) or RD cells (lower plot), cultured in FCS-deficient medium after a 12, 24 or 48 h incubation period. Each column represents the arithmetic mean ± sd of 4 independent experiments.

Conclusion: Kre-Alkalyn proved to exhibit a greater anabolic effect compared to regular creatine. Thus, considering the equivalent controlled conditions of the experiment, the observed greater anabolic effects of Kre-Alkalyn could be ascribed solely to the superior stability afforded by the processing manipulations used to m

[T_Own]

i am on my 3rd day on 1.5grams kre-aklyn and i dont think it has given me strength or energy at all.... im gunna give it 30 days and if i dont notice a difference i am going to mono because im trying to make big gains plus im skinny

gotta give it some time. idk about kre aklyn but 1.5g isn't very much

[SuperLift]

Been awhile since i took kre aklyn but you take 2 servings a day. I think I doubled my serving size to. So I took 6 grams a day for a little over a month. definitely helped me build my strength/weight back ( i was coming back from a 6 month break) Ridiculous of me i know!!!

[AUb27]

no one commenting on that study?? it said kre-alkalyn is better.. the opposite of what the study that drummerboy linked to said.

[jg42058p]

creatine isn't much of an anabolic to begin with... it will only help you do an extra rep or so and maybe give you some size from the water retention.

A lot of guys go on it with big hopes in mind thinking they'll put on gains equivalent to steroids, but they're just fooling themselves... and their money