Austinite's Amino Acids, Vitamins, Minerals, Herbs and more.

[austinite]

I am excited to hear any updates about this. Have you decided how you will administer it yet? I know you were contemplating intravenously.

I'm excited, too! I'm going to start IM for now because I just had a visit with the Endo today and she changed my TRT protocol, so it's easier IM to combine deca /test/B12. too much for subq.

However, I'm just going to do this until I see if I notice a difference. Once I get that figured out I'm going to run it IV for a while.

Also getting a 300,000 iu vitamin D shot on monday. That should be interesting.

[basketballfan22]

I'm excited, too! I'm going to start IM for now because I just had a visit with the Endo today and she changed my TRT protocol, so it's easier IM to combine deca /test/B12. too much for subq.

However, I'm just going to do this until I see if I notice a difference. Once I get that figured out I'm going to run it IV for a while.

Also getting a 300,000 iu vitamin D shot on monday. That should be interesting.

Dear Lord sir! A 300,000 IU shot of vitamin D? That's insane. I take it your megadoses of vitamin D have not significantly improved your vitamin D levels then? Do you have a lot of experience administering shots intravenously? Isn't that a lot more difficult?

Also, whatever happened to your podcasts?

[austinite]

Dear Lord sir! A 300,000 IU shot of vitamin D? That's insane. I take it your megadoses of vitamin D have not significantly improved your vitamin D levels then? Do you have a lot of experience administering shots intravenously? Isn't that a lot more difficult?

Also, whatever happened to your podcasts?

That's what I thought. Then kelkel referred me to some studies showing 600k iu shots. Seems its good enough to dose once every 6 months. Orals dont work for me no matter what.

Podcasts will be coming soon. Just have so much on my plate right now.

[DexterMorgan]

Awesome thread. Looks like I need to take more vitamins.
I'm currently taking B Complex by Jarrow, D3, Calcium, Zinc, Vitamin E and Fish oil

What would you say is a good dose for Vitamin E?

I thought I was taking too many vitamins lol.

[austinite]

Awesome thread. Looks like I need to take more vitamins.
I'm currently taking B Complex by Jarrow, D3, Calcium, Zinc, Vitamin E and Fish oil

What would you say is a good dose for Vitamin E?

I thought I was taking too many vitamins lol.

^ good set supplements you got there man.

If you get basic Vitamin E, 400 iu is good. If you get the prefered Vitamin E tocopherols, 90 iu.

[DexterMorgan]

^ good set supplements you got there man.

If you get basic Vitamin E, 400 iu is good. If you get the prefered Vitamin E tocopherols, 90 iu.

Okay I been taking 400iu. Looks like I got the basic one it says dl-Alpha Tocopheryl Acetate, and Glycerin.
Thanx Austinite

[austinite]

Okay I been taking 400iu. Looks like I got the basic one it says dl-Alpha Tocopheryl Acetate, and Glycerin.
Thanx Austinite

Perfect!

[energizer bunny]

Austinite

here is my supplement schedule for the next 2.5 month to try and get testosterone to rise and my RBC to rise.

Vit C 3000mg per day......morning,after train and before bed
Vit E 800iu per day..........morning and before bed
Vit D3 5000iu per day......morning
Vit B12 methyl 2000mcg per day....morning and night
Magnesium citrate 450mg per day..morning and night
Zinc citrate 50mg per day per day..night
super strength omega 3 6gram per day.....morning and night
Udos oil.......2 table spoons.....night

hows that for my goals? would you up the dose of any? lower the dose? change timings? add anything (money is an issue)

cheers

[austinite]

Austinite

here is my supplement schedule for the next 2.5 month to try and get testosterone to rise and my RBC to rise.

Vit C 3000mg per day......morning,after train and before bed
Vit E 800iu per day..........morning and before bed
Vit D3 5000iu per day......morning
Vit B12 methyl 2000mcg per day....morning and night
Magnesium citrate 450mg per day..morning and night
Zinc citrate 50mg per day per day..night
super strength omega 3 6gram per day.....morning and night
Udos oil.......2 table spoons.....night

hows that for my goals? would you up the dose of any? lower the dose? change timings? add anything (money is an issue)

cheers

That looks great, EB! the only mineral I see missig is copper. You can get a copper/zinc mix to save money. Wait until you run out of zinc. 50mg zinc with 2mg copper is a great ratio.

* copper levels drop when zinc and vitamin C are used by the body.

[energizer bunny]

That looks great, EB! the only mineral I see missig is copper. You can get a copper/zinc mix to save money. Wait until you run out of zinc. 50mg zinc with 2mg copper is a great ratio.

* copper levels drop when zinc and vitamin C are used by the body.

cheers mate, I will add copper.

[torrential]

Austinite,

If I could, I would have PM'd you. I have concerns about taking zinc and copper together. Have you heard of this effect, where high dose zinc knocks out copper:

High intake of zinc induces the intestinal synthesis of a copper-binding protein called metallothionein. Metallothionein traps copper within intestinal cells and prevents its systemic absorption. More typical intakes of zinc do not affect copper absorption and high copper intakes do not affect zinc absorption

I can't post a URL but the reference is from the Linus Pauling Institute at Oregon State University, Micronutrient Information Center, Minerals, Zinc.

High dose zinc "protects" us from heavy metals including environmental copper (tap water, food, etc.) making supplementation essential for us. FWIW, I take my 2mg copper in the morning and my 50mg zinc at night.

[austinite]

Austinite,

If I could, I would have PM'd you. I have concerns about taking zinc and copper together. Have you heard of this effect, where high dose zinc knocks out copper:

High intake of zinc induces the intestinal synthesis of a copper-binding protein called metallothionein. Metallothionein traps copper within intestinal cells and prevents its systemic absorption. More typical intakes of zinc do not affect copper absorption and high copper intakes do not affect zinc absorption

I can't post a URL but the reference is from the Linus Pauling Institute at Oregon State University, Micronutrient Information Center, Minerals, Zinc.

High dose zinc "protects" us from heavy metals including environmental copper (tap water, food, etc.) making supplementation essential for us. FWIW, I take my 2mg copper in the morning and my 50mg zinc at night.

Yes, this has been discussed in this thread heavily.

Zinc at 50mg is not a high dose. There is no interference whatsoever. Even if it did, which it does not... Vitamin E protects copper. Count on NAC to protect you from heavy metals, not Zinc. Take it whenever, don't overthink it. No harm is done.

[torrential]

Thanks Austinite. I read and searched but still managed to miss it.

[austinite]

Thanks Austinite. I read and searched but still managed to miss it.

No problem, buddy.

[austinite]

Study: Pycnogenol + L-Arginine = solution for Erectile Dysfunction.

Investigation of a complex plant extract for mild to moderate erectile dysfunction in a randomized, double-blind, placebo-controlled, parallel-arm study.

OBJECTIVE:
To assess the effects of a complex plant extract (Prelox®, a formulation of pine bark extract and l-arginine aspartate; Horphag Research UK Ltd, London, UK) on erectile dysfunction (ED) in men, as sexual desire typically persists in ageing men, while their erectile and endothelial function gradually declines.

PATIENTS AND METHODS:
In this double-blind, placebo-controlled study we assessed the effects of Prelox in 124 patients (aged 30-50 years) with moderate ED over an investigational period of 6 months. The International Index Of Erectile Function (IIEF) was used to quantify changes in sexual function.

RESULTS:
The erectile domain of the IIEF (questions 1-5 plus 15) improved with Prelox from a baseline mean (sd) score of 15.2 (6.6) to 25.2 (2.1) after 3 months and 27.1 (2.1) after 6 months of treatment. In the placebo group there was an increase from a baseline score of 15.1 (7.0) to 19.1 (3.0) and 19.0 (3.1) after 3 and 6 months, respectively. The effects with Prelox were statistically significant compared with placebo (P < 0.05). Mean (SD) total plasma testosterone levels increased significantly from 15.9 (2.3) to 18.9 (2.6) nmol/L (P < 0.05) after 6 months with Prelox, compared to an increase from 16.9 (2.4) to 17.3 (2.3) nmol/L in the placebo group.

CONCLUSION:
This study shows that Prelox is effective for improving erectile function, and that this effect persists on continuous therapy for up to 6 months. Moreover, there is some evidence that erectile function continues to improve the longer the therapy is used.

PMID: 20184576

[Java Man]

I injected 1mg B complex (1mg b-12 plus ancillary b vitamins in various amounts) human grade. IM. This morning. I'm starving even though I have been eating normally today. I don't feel full like I usually do. Is this what injecting B12 IM feels like or am I just unusually hungry today? It's my 1st time with injectable B12. Always took sub lingual at 5k mcg daily before.

[austinite]

I injected 1mg B complex (1mg b-12 plus ancillary b vitamins in various amounts) human grade. IM. This morning. I'm starving even though I have been eating normally today. I don't feel full like I usually do. Is this what injecting B12 IM geeks like or am I just unusually hungry today? It's my 1st time with injectable B12. Always took sub lingual at 5k mcg daily before.

LOL! Welcome to "Bulking whether you like it or not".

What you have is hydroxocobalamin. It must be converted by your body into methyl in order to be functional. The conversion process is certainly better than Cyanocobalamin, so it's superior to Cyano.

I'm thinking of mixing that with Methyl. So much B12 experimenting lately it's driving me nuts.

[Java Man]

Lol. Awesome. Why didn't I try this 20yrs ago. I've been throwing my $ away on oral B12 for years!

[austinite]

Lol. Awesome. Why didn't I try this 20yrs ago. I've been throwing my $ away on oral B12 for years!

Does it sting a little? some folks don't complain but lots of people say hydroxy stings.

Yeah, anyone that says orals are comparable is lying to ya.

[Java Man]

Yes but nothing like pip from some AAS I've done. It's 1.5% ba so I expected it to sting a little, oral B is useless compared to this. Night and day man.

[Java Man]

an interesting excerpt from the wiki page on hydroxocobalamin:

Experimental uses as nitric oxide scavenger and anti-inflammatory

Hydroxycobalamin is a scavenger of nitric oxide, as well as cyanide, and has been used experimentally to modify nitric oxide-mediated inflammation. For example, a hydoxocobalamin skin creme was found to reduce chronic skin inflammation. [8]

Hydroxycobalamin has also been used in a pilot-study treatment of migraines, as an inhibitor of nitric oxide-induced vasodilation. [9]

Source:
Hydroxocobalamin - Wikipedia, the free encyclopedia

[basketballfan22]

an interesting excerpt from the wiki page on hydroxocobalamin:



Source:
Hydroxocobalamin - Wikipedia, the free encyclopedia

I am glad you posted that because I was just going to inquire about the advantages of hydroxocobalamin. If your body converts this to methylcobalamin, I don't understand why one should not just take methylcobalamin.

[austinite]

^ Because conversion process does not result in 100% of what you took. So some goes to waste. Anything You take in has to be converted to either Methyl or Adenosyl.

There are several types of B12 that you can use. I'll list them in the most effective order:

1. Methylcobalamin
2. Adenosylcobalamin
3. Hydroxocobalamin
4. Cyanocobalamin

Methylcobalamin is more bioactive than any other and obviously does not require conversion by the body to methyl; the form that's most beneficial to support red cells and your nervous system. This one is necessary to break down homocysteine (breakdown of non-protein amino acids).

Adenosylcobalamin, the second on the list is really just as effective as Methyl. This is because it's also a form that is useful, as other forms of B12 would have to convert to either Adenosyl or Methyl. This one is a key player in metabolic pathways.

Hydroxocobalamin must be converted by your body into methyl in order to be functional as stated above. The conversion process is certainly better than Cyanocobalamin, which is why it's third on the list.

Cyanocobalamin is the one you find in just about every supplement. One of the reasons for that is because it's cheap to produce; making supplements cost effective, but unfortunately, not result effective. It's named Cyano because it's attached to the cyanide molecule. After the conversion process, very little methyl results.

[basketballfan22]

^ Because conversion process does not result in 100% of what you took. So some goes to waste. Anything You take in has to be converted to either Methyl or Adenosyl.

There are several types of B12 that you can use. I'll list them in the most effective order:

1. Methylcobalamin
2. Adenosylcobalamin
3. Hydroxocobalamin
4. Cyanocobalamin

Methylcobalamin is more bioactive than any other and obviously does not require conversion by the body to methyl; the form that's most beneficial to support red cells and your nervous system. This one is necessary to break down homocysteine (breakdown of non-protein amino acids).

Adenosylcobalamin, the second on the list is really just as effective as Methyl. This is because it's also a form that is useful, as other forms of B12 would have to convert to either Adenosyl or Methyl. This one is a key player in metabolic pathways.

Hydroxocobalamin must be converted by your body into methyl in order to be functional as stated above. The conversion process is certainly better than Cyanocobalamin, which is why it's third on the list.

Cyanocobalamin is the one you find in just about every supplement. One of the reasons for that is because it's cheap to produce; making supplements cost effective, but unfortunately, not result effective. It's named Cyano because it's attached to the cyanide molecule. After the conversion process, very little methyl results.

Nah man, that's the point I was making. That's why I asked why would anyone NOT use methylcobalamin. You said you were thinking about combining the two types of B12. I don't understand why when you already have the "best" one.

[austinite]

Nah man, that's the point I was making. That's why I asked why would anyone NOT use methylcobalamin. You said you were thinking about combining the two types of B12. I don't understand why when you already have the "best" one.

Because hydroxy is the one that comes in complex.

[Java Man]

I am glad you posted that because I was just going to inquire about the advantages of hydroxocobalamin. If your body converts this to methylcobalamin, I don't understand why one should not just take methylcobalamin.

its a lot less expensive than methyl for one thing. My supp bill is immense right now so I went with this as the guinea pig. I'll be getting methyl later.

edit: I'll probably mix this hydrxo complex with methyl because I like having the other B's supporting the b12. Thanks Aus!

[basketballfan22]

Because hydroxy is the one that comes in complex.

What do you mean by that?

[austinite]

What do you mean by that?

It contains multiple B vitamins, not just B12.

[basketballfan22]

It contains multiple B vitamins, not just B12.

What ones in particular, and what is the typical vitamin B profile like? The only other one I plan to supplement with is B6 (oral).

[austinite]

Depends on who makes it. Here's mine, which is a common blend...

Each ML contains:

1000 mcg of B12 Hydroxy
50 mg of B1
5 mg of B6
5 mg of B2
50 mg of B3
5 mg of B5
25 mg of Methionine
50 mg inositol
50 mg Choline

[basketballfan22]

Depends on who makes it. Here's mine, which is a common blend...

Each ML contains:

1000 mcg of B12 Hydroxy
50 mg of B1
5 mg of B6
5 mg of B2
50 mg of B3
5 mg of B5
25 mg of Methionine
50 mg inositol
50 mg Choline

Aren't those very small doses, especially the vitamin B6 dose? I plan to take 100 mg of B6 every Sunday, granted it will be orally; but still. I know how critical you are of multivitamins because of their small doses, so I am interested in hearing your reasoning for this.

[austinite]

Aren't those very small doses, especially the vitamin B6 dose? I plan to take 100 mg of B6 every Sunday, granted it will be orally; but still. I know how critical you are of multivitamins because of their small doses, so I am interested in hearing your reasoning for this.

Yes, they're small doses, but still effective when injected and enough to support each other. Orals work, but as we've discussed, they will always be limited. It also depends on how frequently you plan on injecting, so in some cases, these doses are not small at all.

My goal is to eventually rid myself of as many pills as possible. One of these days I'll have a B complex/amino acid mix that I inject once weekly. (I hope!)

[basketballfan22]

Yes, they're small doses, but still effective when injected and enough to support each other. Orals work, but as we've discussed, they will always be limited. It also depends on how frequently you plan on injecting, so in some cases, these doses are not small at all.

My goal is to eventually rid myself of as many pills as possible. One of these days I'll have a B complex/amino acid mix that I inject once weekly. (I hope!)

I wish you luck! Is 5 mg IM really comparable to 100 mg orally? You plan to inject B12 only once per week so that means you will only be doing B6 once per week too.

[austinite]

I wish you luck! Is 5 mg IM really comparable to 100 mg orally? You plan to inject B12 only once per week so that means you will only be doing B6 once per week too.

Yes, but this is a pharmacy blend, not my blend. So my blend would be dosed higher.

It's hard to say if 5mg injected is comparable to 100mg orally. I'd say, considering the poor absorption of orals, and the instant benefit of the injection (which you get 100% of), it's tough to say but I'd say that 10mg would be comparable without a doubt.

[Doom44]

Aust what is DHEA function ? thanks

[austinite]

Aust what is DHEA function ? thanks

From the HRT section...

DHEA Supplementation
Dehydroepiandrosterone: DHEA
As presented by Dr. Neal Rouzier, M.D.

Here's a great reason to add DHEA to your protcol.

DHEA is a hormone secreted primarily by the adrenal glands. It results in a shift of a catabolic state to an anabolic or protein building state.

 It reduces cardiovascular risks by increasing lipolyses (decrease visceral fat).
 It stimulates the immune system, restores sexual vitality, improves moods, decreases cholesterol and body fat.
 It improves memory, increases energy, and has anti-cancer properties by enhancing the immune system.
 It is an endocrine precursor to other hormones, prevents immuno-senescence, loss of sleep, osteoporosis, atherosclerosis.
 DHEA reduces insulin requirement
 Adrenal hormone anabolic vs. catabolic metabolism
 Restores immunity
 Prevents osteoporosis, increases bone density
 Prevents cancer in lab animals
 Prevents diabetes & heart disease
 Decreases visceral fat
 Improves mood & well-being
 Improves energy & memory
 Slows aging process in lab animals
 Prevents lipid peroxidation =
antioxidant
 Endocrine precursor to T.P.E.
 7-keto DHEA is not a precursor to other HRT = avoid
 Neurotransmitter (recently discovered)
 Presently pending FDA approval for Lupus (Prasterone)

Clinically substantiated uses of DHEA include replacement for:
 Low DHEA levels
 Chronic disease
 Adrenal exhaustion or corticosteroid therapy
 SLE
 Improving bone density
 Improving depression & mood disorders
 Enhancing immune response by activating T-cells
 Improving well-being
 Decreasing cardiovascular risk
 Improving erectile dysfunction
 Anyone over 40
 DHEA has never been shown to reverse the aging process
 Nevertheless DHEA is important for preventive medicine
 DHEA inhibits synthesis of thromboxane A2, reduces plasminogen activator inhibitor, and tissue plasminogen activator
– all decreasing platelet aggregation and ischemia.

Administraiton:
Men<200lb: 50mg AM
Men>200lb: 75-100mg AM

Women <50yo: 10-15mg AM
Women >50yo: 25mg AM

IMPORTANT:
DHEA Serum Levels
 MEN
 Range 100-600
 Optimal 500-600
WOMEN
 Range 50-300
 Optimal 200-250

Higher levels in women predispose them to side effects – therefore stay low
 Monitor monthly until optimal
 Assure correct dose and compliance
 Measure DHEA-S and not DHEA

 Side effects: acne, hirsutism
 Tx: Lower dose or take QOD Spironolactone 100 mg/day
 Contraindicated in sex hormone responsive tumors – breast, ovarian, uterine, prostate
 Conversion to T.P.E.?
 DHEA raises testosterone levels in women slightly, yet not in men
 DHEA raises estradiol slightly in men

Indications:
 Over age 40 for health protection
 Preventive medicine and well-being
 Symptoms of aging, mood & depression
 ‘Cause the medical literature suggests it if we want to live longer, happier, healthier

DHEA – S04
 MEN Blood levels
 Optimal : 500-600 ug/ml
 Side effects rare in men
WOMEN
 Optimal : 200-250 ug/ml
 Dose based on side effects
 Side effects very common in women

DHEA Dose
 MEN
 Capsule – SR micronized
 50 mg Q am
 >200 lbs – 75 - 100 mg Q am

WOMEN
 Capsule – SR micronized
 10 mg Q am if over 40
 15 mg Q am if over 50
 25 mg Q am if over 60
 If under age 40, do not prescribe due to sensitivity causing side effects.

[Doom44]

From the HRT section...

DHEA Supplementation
Dehydroepiandrosterone: DHEA
As presented by Dr. Neal Rouzier, M.D.

Here's a great reason to add DHEA to your protcol.

DHEA is a hormone secreted primarily by the adrenal glands. It results in a shift of a catabolic state to an anabolic or protein building state.

 It reduces cardiovascular risks by increasing lipolyses (decrease visceral fat).
 It stimulates the immune system, restores sexual vitality, improves moods, decreases cholesterol and body fat.
 It improves memory, increases energy, and has anti-cancer properties by enhancing the immune system.
 It is an endocrine precursor to other hormones, prevents immuno-senescence, loss of sleep, osteoporosis, atherosclerosis.
 DHEA reduces insulin requirement
 Adrenal hormone anabolic vs. catabolic metabolism
 Restores immunity
 Prevents osteoporosis, increases bone density
 Prevents cancer in lab animals
 Prevents diabetes & heart disease
 Decreases visceral fat
 Improves mood & well-being
 Improves energy & memory
 Slows aging process in lab animals
 Prevents lipid peroxidation =
antioxidant
 Endocrine precursor to T.P.E.
 7-keto DHEA is not a precursor to other HRT = avoid
 Neurotransmitter (recently discovered)
 Presently pending FDA approval for Lupus (Prasterone)

Clinically substantiated uses of DHEA include replacement for:
 Low DHEA levels
 Chronic disease
 Adrenal exhaustion or corticosteroid therapy
 SLE
 Improving bone density
 Improving depression & mood disorders
 Enhancing immune response by activating T-cells
 Improving well-being
 Decreasing cardiovascular risk
 Improving erectile dysfunction
 Anyone over 40
 DHEA has never been shown to reverse the aging process
 Nevertheless DHEA is important for preventive medicine
 DHEA inhibits synthesis of thromboxane A2, reduces plasminogen activator inhibitor, and tissue plasminogen activator
– all decreasing platelet aggregation and ischemia.

Administraiton:
Men<200lb: 50mg AM
Men>200lb: 75-100mg AM

Women <50yo: 10-15mg AM
Women >50yo: 25mg AM

IMPORTANT:
DHEA Serum Levels
 MEN
 Range 100-600
 Optimal 500-600
WOMEN
 Range 50-300
 Optimal 200-250

Higher levels in women predispose them to side effects – therefore stay low
 Monitor monthly until optimal
 Assure correct dose and compliance
 Measure DHEA-S and not DHEA

 Side effects: acne, hirsutism
 Tx: Lower dose or take QOD Spironolactone 100 mg/day
 Contraindicated in sex hormone responsive tumors – breast, ovarian, uterine, prostate
 Conversion to T.P.E.?
 DHEA raises testosterone levels in women slightly, yet not in men
 DHEA raises estradiol slightly in men

Indications:
 Over age 40 for health protection
 Preventive medicine and well-being
 Symptoms of aging, mood & depression
 ‘Cause the medical literature suggests it if we want to live longer, happier, healthier

DHEA – S04
 MEN Blood levels
 Optimal : 500-600 ug/ml
 Side effects rare in men
WOMEN
 Optimal : 200-250 ug/ml
 Dose based on side effects
 Side effects very common in women

DHEA Dose
 MEN
 Capsule – SR micronized
 50 mg Q am
 >200 lbs – 75 - 100 mg Q am

WOMEN
 Capsule – SR micronized
 10 mg Q am if over 40
 15 mg Q am if over 50
 25 mg Q am if over 60
 If under age 40, do not prescribe due to sensitivity causing side effects.

wow. it look awesome. thanks aust

[RaginCajun]

hey aust, is there any way to put/keep your body at a high nitrogen retention level?

I think this is one of my main culprits to my joints aching and making all types of noises.

what are your thoughts on how to achieve this without the help of Nor-19s like Deca ?

[austinite]

^ Well yeah, deca will certainly help. I run it year round. Other than that, arginine and glycine are best for nitrogen retention.

[RaginCajun]

^ Well yeah, deca will certainly help. I run it year round. Other than that, arginine and glycine are best for nitrogen retention.

thanks.

I know I must have some type of deficiency in nitrogen or something. once I get a joint back in place, it pops right back out again. my tendons must be weak also.