T3: A complete guide to cycling T3 and how it works

[Brett N]

Crap, bottle that ar-r shipped said nothing about refrigerating. Mine has been sitting for a week in a cool closet. Is it screwed or will it be ok if I start refrigerating now?

[austinite]

Crap, bottle that ar-r shipped said nothing about refrigerating. Mine has been sitting for a week in a cool closet. Is it screwed or will it be ok if I start refrigerating now?

It'll be fine. Just put it in the fridge. Honestly, I am merely following their recommendation. I've used non-refrigerated T3 with no difference.

[Vettester]

First if all great read austinite as usual very education.
Secondly can I ask are the dose, effects and risks the same for men and women?

Therapeutic dosages tend to range from 12.5mcg to 25mcg/day, and up to 50mcg (dependent on assay results), but like anything, starting out should be small (5mcg) and titrate up to the optimal dosage suggested by a physician. Keep in mind, women facing peri-menopausal and post menopausal symptoms will tend to have other conditions with the adrenals and iron/ferritin, which needs to factored before supplementing T3, or any natural desiccated thyroid medication. Various conditions like pooling seem to exist more in women in the peri/post meno stages, usually due to a iron deficiency and cortisol imbalance. As mentioned, supplementing products like iron at the same time with T3 can render its efficacy. A lot of female BHRT doctors will split up the dosages 2x day, 1st dose at the time of rising. Iron and B12 supplements could be at lunch time.

Labs will be crucial, and with women, I can't stress the Iron/Ferritin and Adrenal (cortisol saliva, DHEA, ..), and proper thyroid labs -FT4, FT3, RT3, Thyroid Antibodies. If a physician just goes by TSH, time to move on. To really determine what a patient NEEDS, they need to rule out Hashis, Graves, etc., and/or other possible pathologies that might be loosely related, but causing inflammation that are directly effecting these glands and the function thereof.

[austinite]

Therapeutic dosages tend to range from 12.5mcg to 25mcg/day, and up to 50mcg (dependent on assay results), but like anything, starting out should be small (5mcg) and titrate up to the optimal dosage suggested by a physician. Keep in mind, women facing peri-menopausal and post menopausal symptoms will tend to have other conditions with the adrenals and iron/ferritin, which needs to factored before supplementing T3, or any natural desiccated thyroid medication. Various conditions like pooling seem to exist more in women in the peri/post meno stages, usually due to a iron deficiency and cortisol imbalance. As mentioned, supplementing products like iron at the same time with T3 can render its efficacy. A lot of female BHRT doctors will split up the dosages 2x day, 1st dose at the time of rising. Iron and B12 supplements could be at lunch time.

Labs will be crucial, and with women, I can't stress the Iron/Ferritin and Adrenal (cortisol saliva, DHEA, ..), and proper thyroid labs -FT4, FT3, RT3, Thyroid Antibodies. If a physician just goes by TSH, time to move on. To really determine what a patient NEEDS, they need to rule out Hashis, Graves, etc., and/or other possible pathologies that might be loosely related, but causing inflammation that are directly effecting these glands and the function thereof.

Outstanding. Thank you, Vette! We can always count on you

[teezer33]

Great reading, the only thing I would add would be to wait 4 hours before taking vitamins. apparently it will destroy the effects of T3, according to me Endo.

[austinite]

Great reading, the only thing I would add would be to wait 4 hours before taking vitamins. apparently it will destroy the effects of T3, according to me Endo.

i haven't seen any evidence to this.

[teezer33]

i haven't seen any evidence to this.

I found this on drugs.com

The timing of meals relative to your levothyroxine dose can affect absorption of the drug. Therefore, levothyroxine should be taken on a consistent schedule with regard to time of day and relation to meals so as to maintain steady blood levels. In addition, absorption of levothyroxine may be decreased by foods such as soybean flour, cotton seed meal, walnuts, dietary fiber, calcium, and calcium fortified juices. These foods should be avoided within several hours of dosing if possible.

Drug Interaction Report - Drugs.com

I was told to wait an hour before meals, and 4 hours for vitamins for proper absorbtion

[austinite]

I found this on drugs.com The timing of meals relative to your levothyroxine dose can affect absorption of the drug. Therefore, levothyroxine should be taken on a consistent schedule with regard to time of day and relation to meals so as to maintain steady blood levels. In addition, absorption of levothyroxine may be decreased by foods such as soybean flour, cotton seed meal, walnuts, dietary fiber, calcium, and calcium fortified juices. These foods should be avoided within several hours of dosing if possible. Drug Interaction Report - Drugs.com I was told to wait an hour before meals, and 4 hours for vitamins for proper absorbtion

yea those are articles. There really isn't any scientific evidence to this. I'll do some more research but I take it at the same time with zero adverse effects.

[Vettester]

Outstanding. Thank you, Vette! We can always count on you

Thanks Aus! I only wish I had more time like before. Hopefully things will settle a bit over the holidays. Great stuff you put together on the opening post!! The thyroid function is as complex as it is intriguing! Maybe at some point we can collaborate on thyroid sticky in the HRT section, as hypogonadism and the thyroid conditions go hand-n-hand.

[adrenaline99]

So I just received my liquid t3 from ar-r and had a question about the oral syringe it came with. Everytime I try to dose it right it traps a large air bubble next to the plunger, is there anyway to eliminate all of the air in the oral syringe in order ro get the full dose? Thanks!

[austinite]

So I just received my liquid t3 from ar-r and had a question about the oral syringe it came with. Everytime I try to dose it right it traps a large air bubble next to the plunger, is there anyway to eliminate all of the air in the oral syringe in order ro get the full dose? Thanks!

disregard the bubble. Just be sure the liquid is at the mark of your choice.

[athletic.guy]

Im on 100ug t3 ed for a couple weeks on a low carb, low cal diet. I'm sweating all day, but not lost BF.

HOW LONG DOES IT TAKE TO START WORKING?

I'm at 20% bf trying to get down to 10 in 12 weeks. Ill stick with 100ug and Austinites diet supp list- chromium, EGCG, And synephrine stack along with ECA, L Carntine injections (900mg week), caffeine.

Ok, I wrote the above post earlier. I have actually now been testsd and have lost 5% bf on your stacks.... But maintained weight.....

Saying all that my diet is calculated, weighted and almost perfect everyday.

I'm only using 50ug a day but plan to for 3 months. Your weight loss stack is great too with no sides.

My weight possibly hasn't dropped because I'm holding more water, my e2 is through the roof ATM due to not responding well to my AI's.

[Brett N]

I have been on the ar-r T3 for 15 days as of today. I am taking .3ml which is 60mg. My body temperature has not risen at all yet. I have been taking the T3 the same time every day and my temp the same time. I have not increased the Test I am taking. I am only on 100mg a week for TRT, I may increase if I notice muscle loss.

Any suggestions? Should I increase amount of T3? Am I doing something wrong?

[austinite]

Any body aches, Brett?

[Brett N]

Yea, really rough the last 2 days. Last night I noticed my squat dropped quite a bit. Normally, I could rep 285x9 and I could only do 285x4 and it was tough as hell.

Several muscle groups are feeling really sore like I worked them real hard but I didn't.

[austinite]

Yea, really rough the last 2 days. Last night I noticed my squat dropped quite a bit. Normally, I could rep 285x9 and I could only do 285x4 and it was tough as hell.

Several muscle groups are feeling really sore like I worked them real hard but I didn't.

OK just continue with your protocol. It's working. The aching should subside soon.

[athletic.guy]

I've stopped my t3 until I get my hormones back into check. I've stopped all my test e shots as u may know too. Hopefully it only take a week or so then plan on continuing, do u think its ok to stop t3 for a week then start again or should I stay off a lil longer??? Or it doesn't really matter, just continue with 50ug ed without test for now ??

[austinite]

Why would you stop for a week and continue? I don't understand. What exactly do you mean by "Hormones back in check"? If no blood panels are being ordering I wouldn't bother really. I need details, lots of them...

[athletic.guy]

I'm having extremely high estrogen issues ATM. So ill just continue T3 @ 50ug ed because its unrelated to my high e2.

Thanks Aust.

[ricorico]

Thank you for all the great information and effort put into this.

[Reiid13]

I'm having extremely high estrogen issues ATM. So ill just continue T3 @ 50ug ed because its unrelated to my high e2.

Thanks Aust.

Pull out the big guns get letro then if that dont work visit doctors

[Reiid13]

To preserve muscle , would primo be better to take than test e to stay more lean ? Would you need a pct still of nolvadex and clomid ?

[austinite]

To preserve muscle , would primo be better to take than test e to stay more lean ? Would you need a pct still of nolvadex and clomid ?

No, primo only would be a terrible choice.

Yes, you need PCT after any and every suppressing compound.

[mikemike12]

Great Article.

I have a few questions about coming off T3

1. How long approx till thyroid function returns to normal? I will be using for 4 weeks at 50mcg ED.

2. Is there any way to tell if your thyroid is up and running again short of a doctor visit?

3. When coming off T3 'cold-turkey', should calories be lowered to offset the dramatic decrease in metabolic rate until thyroid is back to normal?

[mikemike12]

Great Article.

I have a few questions about coming off T3

1. How long approx till thyroid function returns to normal? I will be using for 4 weeks at 50mcg ED.

2. Is there any way to tell if your thyroid is up and running again short of a doctor visit?

3. When coming off T3 'cold-turkey', should calories be lowered to offset the dramatic decrease in metabolic rate until thyroid is back to normal?

bump for answers

[austinite]

Great Article.

I have a few questions about coming off T3

1. How long approx till thyroid function returns to normal? I will be using for 4 weeks at 50mcg ED.

2. Is there any way to tell if your thyroid is up and running again short of a doctor visit?

3. When coming off T3 'cold-turkey', should calories be lowered to offset the dramatic decrease in metabolic rate until thyroid is back to normal?

1. A few hours maybe.
2. Sure, blood work.
3. Yeah, but that math would be mind boggling to figure out...

[mikemike12]

1. A few hours maybe.
2. Sure, blood work.
3. Yeah, but that math would be mind boggling to figure out...

Thanks for for the response.


You are saying my thyroid will be producing 25mcg T3 ED starting a few hours after I stop use? That doesn't sound right. Did you mean days?

[austinite]

Yes. Thyroid, as stated, recovers quickly. You'd have to be on for a year for it to take days to recover. People on for 20 years recovered in a few weeks.

[mikemike12]

Yes. Thyroid, as stated, recovers quickly. You'd have to be on for a year for it to take days to recover. People on for 20 years recovered in a few weeks.

Awesome. Thanks again.

[Brett N]

austinite, similar to question above. I have been on 60mg T3 for 3 weeks. Went to GP today complaining of arthritis in my hands, just wanting some celebrex or something. He dicides that I need bloodwork. He says, while we're at it...lets test for Thyroid, cholesterol, and a ton of other stuff. Not test or anything TRT related though.

Question - will my thyroid test show that it looks like it is over producing since I am taking 60mg? If I stopped now (last night last dose) when would my blood test show the normal levels?

[austinite]

YOU MEAN MICROGRAMS? ANd yes, your TSH will be shut down and free will be elevated.

[Giggle]

Aust and Vettster - I sure wish you could guide me. I've been slowly leaning out over the summer, but have hit a plateau. I've been using the fat loss protocol for 2 months (with on and off weeks) with good results - but I'm just not satisfied yet.

I was planning to start at 25 mcg and bump up from there. I'm in a growth phase - but hoping to lean out a bit as well.
Any thoughts?

[austinite]

Aust and Vettster - I sure wish you could guide me. I've been slowly leaning out over the summer, but have hit a plateau. I've been using the fat loss protocol for 2 months (with on and off weeks) with good results - but I'm just not satisfied yet.

I was planning to start at 25 mcg and bump up from there. I'm in a growth phase - but hoping to lean out a bit as well.
Any thoughts?

If you're in growth, you might stay lean, I don't know about leaning out even more while growing. That takes many moons to do. I'm still learning more about the female body and Vettester is the best teacher, so hopefully we both hear from him.

[Vettester]

Aust and Vettster - I sure wish you could guide me. I've been slowly leaning out over the summer, but have hit a plateau. I've been using the fat loss protocol for 2 months (with on and off weeks) with good results - but I'm just not satisfied yet.

I was planning to start at 25 mcg and bump up from there. I'm in a growth phase - but hoping to lean out a bit as well.
Any thoughts?

Hey Giggles, I just happened to take a quick glance at this thread and saw your post. Looking at your profile, I'm presuming you are post-meno? IMO, I'd start a little lighter then titrate up from there; maybe 5 to 10mcg, see how you feel. If by chance you have some fairly recent labs, I'd really be interested ... We don't have to muck up this good thread, so maybe we can chat more in the female HRT section? I'm obviously going for other areas that might be contributing to your plateau, which may easily be part of the solution, i.e., DHEA/adrenals, test serum and free, B12, D3, etc., ... Also any comprehensive thyroid panels showing its activity.

[Giggle]

Thanks - I'll gather up some labs and post them up over there in a few days.
Appreciate the help!

Hey Giggles, I just happened to take a quick glance at this thread and saw your post. Looking at your profile, I'm presuming you are post-meno? IMO, I'd start a little lighter then titrate up from there; maybe 5 to 10mcg, see how you feel. If by chance you have some fairly recent labs, I'd really be interested ... We don't have to muck up this good thread, so maybe we can chat more in the female HRT section? I'm obviously going for other areas that might be contributing to your plateau, which may easily be part of the solution, i.e., DHEA/adrenals, test serum and free, B12, D3, etc., ... Also any comprehensive thyroid panels showing its activity.

[austinite]

Good call, Giggle. I'll be attending, if you don't mind

Thanks, Vette.

[aquarius66794]

Just wanted to chime in and thank aus. for the awesome information. You should consider writing a book, knowledge deserves compensation. I wanted to ask if you think a T3/clen cycle would be even more beneficial while doing your CES stack?

Thanks

[austinite]

Just wanted to chime in and thank aus. for the awesome information. You should consider writing a book, knowledge deserves compensation. I wanted to ask if you think a T3/clen cycle would be even more beneficial while doing your CES stack?

Thanks

Thanks for the kind words, brother.

If you add anything to the CES stack, it would no longer be the CES stack. So I recommend that you do not add anything.

[bass]

Hey Austinite, i want to rum T3 cycle but also rolax cycle, i know i can't run both together, but not sure if there is an advantage running T3 first or Rolax first. any suggestions?

[austinite]

No real advantage. I guess it's all dependent on the purpose of Ralox. If Ralox is being used to resolve a condition, then I would get that out of the way first.