Introduction
Oxytocin (aweksee-Tow-Sin), is a hormone secreted by the pituitary. I was prescribed this drug to combat retarded (delayed) ejaculation. My prescription is dosed at 10 IU, and instructed me to take the sublingual tablet 15 minutes prior to sexual activity. It certainly worked in that aspect. Spoke to Kelkel a few times about this drug. After exchanging a few studies and articles, I decided to run an experiment with dosing it daily. This thread will detail my experiment and experience.
Objective:
This drug has been touted as the "Love Drug". The slogan is in reference to development of better relationships between partners. Furthermore; it is claimed that this drug betters your social interactions and give you a "happy" all day feeling. My goal was to verify some, or all of these claims.
I also wanted to monitor pituitary hormones to observe any possible reactions/changes in serum. This will be outlined shortly.
Quick Disclaimer:
The relationship part may be difficult to narrow down. Without getting into too much detail, shortly before starting this experiment, I met a broad who I am pretty crazy about. So I'm having a difficult time identifying any "boost" in affection towards her. It certainly hasn't gotten any worse, and if you know me at all, it probably should have by now.
The Drug and Protocol:
The prescription I have is dosed at 10 IU. My protocol was to take the compound daily in the morning for 1 week. I then increased the dose to twice daily. This drug is available in nasal spray form as well. It's claimed that nasal sprays are most effective, but after hearing from several users, I am doubting that. I also am not very confident in recommending an over the counter compound. It shouldn't be very difficult to obtain a prescription, but if you choose to run this compound and you're unable to get it prescribed, I guess you have no choice. It very well may work, but my experience is limited to prescription Oxytocin.
Oxytocin is very short lived. Peak serum is observed in approximately 30 minutes with a safe return to baseline in a mere 2.5 hours.
The Experiment:
To minimize any confusion for myself, I dropped two compounds from my daily supplements: L-Tryptophan and L-Theanine.
The first couple of days, I did not notice any noticeable changes. My days went by as any other day did without the drug. On the 3rd day however, I experienced a random erection while at work. This was unusual for me as I am on a twice daily dose of Cialis and have never had this occur. So it certainly is not the Cialis. Nothing else to report for day 3.
On the 4th day, I had a seemingly better day at work. I felt overly friendly, if you will. I was off the next day and felt good. But didn't feel any need to interact or go out and socialize. Back to work the next day and again, super friendly me is back. An employee commented after I got off the phone. She said I was very "animated" today. She said I was using hand gestures as I was speaking on the phone, as if the person were right in front of me. Never done that before, so that's new.
I called my endocronologist and asked her to increase my dosing frequency. She said.. "Oh really"? To which I replied, yeah.. I met someone (True, but not the reason, ha). So now my prescription is for 60 doses per month at the same 10 IU per sublingual tablet.
The second week consisted of 2 doses daily. One at 7:00 am & another at 10:00 am. I wanted to give it a 30 minute buffer to be sure I am back to baseline. I did not want to attempt compounding the drug in my system this weak. No special reason, just part of the experience as the compounding attempt will come later.
Days 10 and 11 were a bit odd. I experienced headaches. The headaches were mild and did not affect my work or focus. I was still in a good mood. But I decided to drop the second dose to see if there was any possible correlation. Well, sure enough, the 12th day, a single dose was administered and no headaches occurred. My ideology here is the timing. This is a considerably low dose, so I don't see how it could have an impact on headaches. I think that the 30 minute break I took between doses was either too short, or too long. The sudden increase in serum after a full return to baseline may have contributed. We know that one dose did not cause headaches. So maybe allowing it to compound prior to return to baseline would be ok, or allowing several hours prior to second dose.
I continued with a single dose for the remainder of the second week with no issues. During that week, sexual experience was outstanding. Of course, I'll refer you back to the disclaimer; this is a new relationship and it may be the newness yielding such effects. Either way, I felt great and certainly can attest to better social interaction. I like to think of myself as very good socially, but that week I felt pretty darn good, notably good.
The start of the 3rd week was confusing. The first couple days were great, but then it suddenly all wore off. It's as if I am no longer taking the drug. I don't get it. I even felt down at one point mid-week. I dropped the compound on the 6th day of week 3. I did not get back on either tryptophan or theanine.
I stayed off the drug for 4 days. With 5 days left into this experiment, I decided to finish those days with a double dose once daily. So I took 20 IU daily each morning. Well it's back. I feel great once again. Having great days at work and overly friendly once again. I realized that I was not getting any headaches at this dose. This semi-confirms my idea earlier about a single dose, or spacing it out longer than half of an hour.
My Conclusions:
This drug does not need to be used on a continuous basis. It should be used on an "as needed" basis. If you're feeling down, socially distant or just feel like you're not your usual self, it can be beneficial. I do not recommend that you take it for longer than 7 day at a time. One week on and one week off makes more sense. After a 7 day run, the minimum break I would give it is 3 days.
I do not recommend multiple doses daily unless you take them no later than 1 hour apart, and no more than 3 doses. Ideally, a larger dose once daily should suffice. If you suffer from retarded ejaculation, you can use this drug at 10 to 20 IU about 15 minutes prior to sexual activity. It certainly works in that department.
To sum up my recommended protocols:
10 to 20 IU once daily in the morning for 7 days. Then 3 to 7 days off. (easy protocol, my preferred choice for effectiveness and convenience)
Or...
10 IU every hour for 3 hours maximum. Start in the morning. (Ex. 7am, 8am, 9am) - This one is just inconvenient, but it should work well, possibly better that once daily.
Blood work:
All panels ordered were reported by Quest Diagnostics.
No changes in the following: GH, IGF-1 (LH/FSH has been in the gutter for years, did not test)
Changes:
Prolactin: Slight increase from baseline of 12 ng/mL to 14 ng/mL. [ reference 2.0-18.0 ng/mL ]
TSH: Slight drop in thyroid stimulating hormone from baseline of 3.3 mIU/L to 2.9 mIU/L [ reference 0.40-4.50 mIU/L ]
Cortisol was not tested because I take medication to manage it. I can't come off medication. I have seen studies indicative of a significant drop in cortisol total.
In closing, this was a short experiment and while it may or may not benefit you, I figured it was worth sharing. But I can certainly say it has benefited me as I now know how I react to the drug in varying doses and protocols. I will use it for at least one week per month. Of course, I will always use it prior to sexual activity as I always have. I tend to develop a little bit of stress towards the end of each month at work. The stress of "Making goal" gets to me at times. So the last week of every month will likely be my week of Oxytocin. I am still interested in observing my reactions with Oxytocin when coupled with Tryptophan and/or Theanine.
Finally, as this was a limited experience, this thread will mostly serve as an informational basis, and I will update any new findings in the future. However, this will likely not be a supported topic. In other words, I may not be able to answer all questions, but I will do my best when I can.
Have a powerful day,
~ Austinite