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Originally Posted by
Khazima
You're essentially correct, you can't 'shock' the muscle. You can overload it with more volume/metabolic fatigue and change the intensity ranges to produce optimal stimulation. If you're doing multiple exercises using multiple rep ranges and varying intensities then you're covering all bases. You could use those same exercises your whole life and do the same workout (ronnie coleman did this) and produce the same gains. Someone constantly varying their exercises etc are just never going to be consistent enough to continuously overload therefore progress.
Drugs also obviously change this, you'll be able to do the same thing or random stuff every time, as long as you go hard enough and eat enough you're going to grow. Structure and planning are not required as much.