Originally Posted by ant_8u
STUDIES
Winny can bind and compete for a position at the progesterone receptor much like Clomid or Nolvadex would at the estrogen receptor, thereby inhibiting progestagenic effects
Now there is evidence that Winny does indeed bind to the progesterone receptor(1) and its users do not indicate the normal characteristics of progesterone stimulation, which bodes well for these anti-progestagenic properties. There is also some clinical data that it does aid in symptoms that require progesterone suppression(2)
References
1 Ellis AJ, Cawston TE, Mackie EJ., The differential effects of stanozolol on human skin and synovial fibroblasts in vitro: DNA synthesis and receptor binding., Agents Actions 1994 Mar;41(1-2):37-43
2 Brestel EP, Thrush LB., The treatment of glucocorticosteroid-dependent chronic urticaria with stanozolol., J Allergy Clin Immunol 1988 Aug;82(2):265-9