Collagen Synthesis - Connective Tissue Strength
THIS IS A VERY IMPORTANT TOPIC. EVERYONE WHO USES AAS SHOULD BE AWARE OF CONNECTIVE TISSUE AND ITS ROLE IN BODY BUILDING. THIS THREAD IS DEDICATED TO GOOD INFO ON AAS AND ITS EFFECT ON COLLAGEN SYNTHESIS (CONNECTIVE TISSUE PRODUCTION) AND WAYS TO INCREASE AND MAINTAIN IT. DIFFERENT AAS HAVE DIFFERENT EFFECTS ON YOUR CONNECTIVE TISSUE, WHICH IS MADE OF COLLAGEN. THIS IS A MAIN AREA OF INJURY, SO PLEASE ADD USEFULL INFO IF YOU HAVE IT. I WILL UPDATE THIS THREAD WITH INFO THAT I FIND DURING MY RESEARCH. HERE IS THE FIRST ARTICLE IVE FOUND, CONCERNING CERTAIN MINERALS AND COLLAGEN SYNTHESIS :
Roles for iron and copper in connective tissue biosynthesis
O'Dell BL.
Both iron and copper play critical biochemical roles in the post-translational modifications of collagen and elastin. These modifications are essential to the maturation and structural integrity of these proteins. Iron functions in the hydroxylation of specific prolyl and lysyl residues in collagen, a process that must occur before the triple helix can form and be extruded from the cell. Copper functions in the oxidative deamination of specific lysyl residues in the soluble forms of both elastin and collagen. This process is essential for crosslink formation and the structural integrity of these proteins. While there is no evidence that nutritional iron deficiency results in connective tissue pathology, copper deficiency impairs crosslink formation and results in gross pathology of bones, lungs and the cardiovascular system of many animal species.
PMID: 6118903 [PubMed - indexed for MEDLINE]