Vitruvian's Steroid Profile of NPP (deca)

[Vitruvian-Man]

Hey, how’s it going everyone?

I know I’m relatively new here, but I have noticed one thing about this forum: No one seems to have a clue what NPP is, or what it is used for! lol

Thus, I’ve decided to create my own steroid -profile for NPP, and simultaneously outline my various experiences with the compound.

For anyone who still doesn’t know what I’m talking about, NPP is a relatively new product, and is considered to be one of the few actively marketed steroids that was produced within the past 10 years.

Disclaimer: I have utilized NPP in basically every protocol: cutting, bulking, and maintaining; however, my advice is all from personal experience. Follow at your own risk, as I am not a certified professional / M.D.

Let’s begin, NPP stands for the chemical name: “nandrolone phenyl-propionate .” It’s often considered the “brother” of Deca , and this is because they are both very similar in molecular structure, with the exception of different esters attached to the molecule. (phenyl-prop v.s. deconate.)

Furthermore, the compounds half-life is around 72 hours, and as a result, there is often debate regarding the timing of NPP injection protocol. (So I’m going to address each of them individually, because injection protocols are completely reliant on goals IMO.)

Benefits of NPP compared to Deca:

a.) Little to no water retention
b.) Instant lubrication of joints, and pain-relief to injection sites.
c.) Fast acting
d.) Compound clears system only a couple of days after secession of use; and does not leave you terribly shut down for prolonged periods of time like deca.
e.) IMO faster recovery of the HPTA after cycle, because of ^^

Downfalls of NPP compared to Deca:

a.) Often a need for more frequent injections
b.) Sometimes can be painful injections

FAQ #1: “Can I utilize NPP for cutting, and how?”

A: Yes absolutely. NPP is a great compound for cutting. It will provide minimal water retention, and stacks very well with prop. Moreover, because it lubricates the joints it has excellent synergy with winstrol (if at a low BF), and eliminates winstrol’s worst side affect – dry joints.

My typical NPP cutter:
(weeks 1 – 10) Prop @ 75mg ED
(weeks 1 – 9) NPP @ 75mg ED
(weeks 5 – 10) Winstrol @ 50mg ED

^^ Notice that when I use Prop with NPP, I follow an “each day injection protocol”

FAQ #2: “Can I utilize NPP for bulking (especially lean bulking??)”

A: YES! Once again, NPP is an excellent choice for this form of bulking. The reason: NPP will provide you with a quick 10 – 15 pounds within 10 weeks of use, until secession of the compound. Moreover, because NPP is fast-acting, one will begin to see the results from it within 5 – 7 days of use. (Also, great strength gains from NPP)

My typical NPP bulker:
(weeks 1 – 14) Test-E @ 600mg EW
(weeks 1 – 13) NPP @ 525mg (each week) but EOD protocol
(weeks 9 – 16) Anavar @ 70mg ED

^^ Notice that during Bulkers I generally inject EOD

FAQ #3: “Can I use NPP similarly to Deca for therapeutic benefits?”

A: ABSOLUTELY! This is one of those things that I feel the medical community will eventually figure out. Often, doctor’s / HRT clinics will prescribe deca @ a low dosage of 100 – 250mg EW for it’s therapeutic benefits. I believe that eventually NPP may take deca’s place.

My typical NPP therapeutic cycle:

(weeks 1 – 10) Test-E @ 200mg
(weeks 1 – 9) NPP @ 200mg EW (but following EOD protocol)

^^ As you can see, I would keep the Test @ a low dosage, perhaps even a TRT dosage. Keep the NPP low, and break the injections up. 50mg x 4 injections a week = 4 injection sites that feel AMAZING, and well lubricated.

FAQ #4: "I like the above protocol ^^ but I don't like injecting.. Can I inject it every 3.5 days with my TRT dosage?"

A: Not a problem. That's another benefit of NPP. The half live of the compound is short, but JUST long enough that it can be used under this protocol.

Typical TRT + Therapeutic Cycle:

(weeks 1 - 10) Test-C @ 100 - 150mg EW
(weeks 1 - 10) NPP @ 100mg x 2 injections per week = ~ 200mg EW.

FAQ #5: "I have Deca, and want to use NPP as a kick-start... is that possible?"

A: YUP! That's fine. Run it the same way you would kick-start with prop on a Test-E cycle.

(weeks 1 - 12) Test-E @ 500mg EW
(weeks 1 - 10) Deca @ 500mg EW
(weeks 1 - 5) NPP @ 75mg ED or 125mg EOD.

Phew, finished. Ok, well I hope you guys enjoyed the read. BTW, I’ve kept all the dosages very moderate on this page, so if anyone has any special circumstances, and want to alter the dosages, or wants to stack additional compounds, etc... feel free to PM me and I’ll try and aid you as much as possible. I have run NPP at extreme dosages, and can relate to most any question . Have a good one boys; Thanks for reading.

***Refer to post #37 for a clinic study regarding NPP.*****
(thanks Dancer)

[gymnerd]

Nice write up. Do you feel the need to wait a couple of weeks to get started with NPP with a long ester test like enanthate to let the test build in the system or just get it on right from the begining?

[Vitruvian-Man]

Nice write up. Do you feel the need to wait a couple of weeks to get started with NPP with a long ester test like enanthate to let the test build in the system or just get it on right from the begining?

Excellent question. And thanks for the compliment bro!

I completely forgot to mention this in the OP.

You do NOT need to start NPP after you begin taking exogenous testosterone ; you can begin stacking the two compounds together from the get-go.

A popular misconception with NPP is that people are scared it will shut you down TOO hard (so they believe you should run test for a couple of weeks to avoid this.) But I'll tell you that's absolutely false. You will have NO libido issues from following this protocol.

^^ However, that said, you can get libido issues while on NPP (because it does shut you down very hard.) However, in that situation, one should consider implementing proviron @ 75mg - 100mg ED (while on cycle). Otherwise, look into viagra.

[gymnerd]

Cool cause I got some plans brewin and npp is in the mix foe sho.

[Vitruvian-Man]

Cool cause I got some plans brewin and npp is in the mix foe sho.

Cool. I home-brew as well. Just for the record:

NPP will best hold @ 100mg/mL. You may be able to get it to stay @ 150mg/mL... but when I last tried my entire batch crashed, so beware.

I know people who claim to get it to hold easily at 200mg/mL.

Good luck.

[c-Z]

Nice write up bro.

[The Deuce]

Great WRITE UP !! REP'ed you dude !!


I utilize NPP in pretty much every cycle that I don't have Tren in.... Just because it is THAT GREAT... Prefer 100times over DECA anyday !!!

[Dont wanna be old]

Good job . Sounds like a very good compound .

[TITANIUM]

Hey, how’s it going everyone?

I know I’m relatively new here, but I have noticed one thing about this forum: No one seems to have a clue what NPP is, or what it is used for! lol

Thus, I’ve decided to create my own steroid -profile for NPP, and simultaneously outline my various experiences with the compound.

For anyone who still doesn’t know what I’m talking about, NPP is a relatively new product, and is considered to be one of the few actively marketed steroids that was produced within the past 10 years.

Disclaimer: I have utilized NPP in basically every protocol: cutting, bulking, and maintaining; however, my advice is all from personal experience. Follow at your own risk, as I am not a certified professional / M.D.

Let’s begin, NPP stands for the chemical name: “nandrolone phenyl-propionate .” It’s often considered the “brother” of Deca , and this is because they are both very similar in molecular structure, with the exception of different esters attached to the molecule. (phenyl-prop v.s. deconate.)

Furthermore, the compounds half-life is around 72 hours, and as a result, there is often debate regarding the timing of NPP injection protocol. (So I’m going to address each of them individually, because injection protocols are completely reliant on goals IMO.)

Benefits of NPP compared to Deca:

a.) Little to no water retention
b.) Instant lubrication of joints, and pain-relief to injection sites.
c.) Fast acting

Downfalls of NPP compared to Deca:

a.) Often a need for more frequent injections
b.) Painful injections (will often sting to inject NPP)

FAQ #1: “Can I utilize NPP for cutting, and how?”

A: Yes absolutely. NPP is a great compound for cutting. It will provide minimal water retention, and stacks very well with prop. Moreover, because it lubricates the joints it has excellent synergy with winstrol (if at a low BF), and eliminates winstrol’s worst side affect – dry joints.

My typical NPP cutter:
(weeks 1 – 10) Prop @ 75mg ED
(weeks 1 – 9) NPP @ 75mg ED
(weeks 5 – 10) Winstrol @ 50mg ED

^^ Notice that when I use Prop with NPP, I follow an “each day injection protocol”

FAQ #2: “Can I utilize NPP for bulking (especially lean bulking??)”

A: YES! Once again, NPP is an excellent choice for this form of bulking. The reason: NPP will provide you with a quick 10 – 15 pounds within 10 weeks of use, until secession of the compound. Moreover, because NPP is fast-acting, one will begin to see the results from it within 5 – 7 days of use. (Also, great strength gains from NPP)

My typical NPP bulker:
(weeks 1 – 14) Test-E @ 600mg EW
(weeks 1 – 13) NPP @ 525mg (each week) but EOD protocol
(weeks 9 – 16) Anavar @ 70mg ED

^^ Notice that during Bulkers I generally inject EOD (it just means larger amounts of oil per injection, and a bit more pain IMO)

FAQ #3: “Can I use NPP similarly to Deca for therapeutic benefits?”

A: ABSOLUTELY! This is one of those things that I feel the medical community will eventually figure out. Often, doctor’s / HRT clinics will prescribe deca @ a low dosage of 100 – 250mg EW for it’s therapeutic benefits. I believe that eventually NPP may take deca’s place.

My typical NPP therapeutic cycle:

(weeks 1 – 10) Test-E @ 200mg
(weeks 1 – 9) NPP @ 200mg EW (but following EOD protocol)

^^ As you can see, I would keep the Test @ a low dosage, perhaps even a TRT dosage. Keep the NPP low, and break the injections up. 50mg x 4 injections a week = 4 injection sites that feel AMAZING, and well lubricated.

Phew, finished. Ok, well I hope you guys enjoyed the read. BTW, I’ve kept all the dosages very moderate on this page, so if anyone has any special circumstances, and want to alter the dosages, or wants to stack additional compounds, etc... feel free to PM me and I’ll try and aid you as much as possible.

Great Job!

Very impressive.

I like fresh research.

I agree with deca becoming out dated.

It is, in itself, a great AAS.

But NPP is falling into the lime light now.

Great for us on AR!

Best

T

[Vitruvian-Man]

Nice write up bro.

Thanks a lot. Great tattoo by the way (mad respect bro.)

Great WRITE UP !! REP'ed you dude !!

I utilize NPP in pretty much every cycle that I don't have Tren in.... Just because it is THAT GREAT... Prefer 100times over DECA anyday !!!

hehe. You talk so oddly. But you have definitely grown on me Deuce. I thank you for the compliment and completely agree, MUCH better then Deca .

Great Job!

Very impressive.
I like fresh research.
I agree with deca becoming out dated.
It is, in itself, a great AAS.
But NPP is falling into the lime light now.
Great for us on AR!
Best
T

Thanks a lot bro. I'm actually writing a real academic paper right now. And could use some support from the members on this site... sooo if you're interested PM me... (and anyone else who reads this and is interested)

Basically, I'm currently working on my next page as a thesis for my Masters degree. It's actually a brilliant topic, and I've begun my research with quite a bit of success. However, I need more personal experiences, etc.

My thesis is going to be a spin off on the standard materia medica (this means basically a holistic description and classification of a specific drug); however, unlike most papers, I'm hoping to correlate the use of exogenous testosterone and it's addictive attributes. My goal is to effectively prove that testosterone has an addictive potential.

[RANA]

Nice write-up. Funny that you wrote this up because I just received my NPP today and I'm just waiting for my prop. I was going to do tren /prop/mast cycle but I am waiting until the spring and I want to try NPP/prop.
Have you had any issue with hair loss on this cycle?

[MuscleScience]

Thanks a lot. Great tattoo by the way (mad respect bro.)



hehe. You talk so oddly. But you have definitely grown on me Deuce. I thank you for the compliment and completely agree, MUCH better then Deca .



Thanks a lot bro. I'm actually writing a real academic paper right now. And could use some support from the members on this site... sooo if you're interested PM me... (and anyone else who reads this and is interested)

Basically, I'm currently working on my next page as a thesis for my Masters degree. It's actually a brilliant topic, and I've begun my research with quite a bit of success. However, I need more personal experiences, etc.

My thesis is going to be a spin off on the standard materia medica (this means basically a holistic description and classification of a specific drug); however, unlike most papers, I'm hoping to correlate the use of endogenous testosterone and it's addictive attributes. My goal is to effectively prove that testosterone has an addictive potential.

What was your undergrad degree in???

[Vitruvian-Man]

What was your undergrad degree in???

Biological Psychology.

Specializing in psycho-active drugs and their effects on the human brain.

[Vitruvian-Man]

Have you had any issue with hair loss on this cycle?

NPP and prop will be quite a nice cycle. Are you using it for a cutter, or for bulking?

Regarding the hair-loss, NPP is actually known for being quite mild compounds, in terms of speeding up male pattern baldness.

[marcus300]

Also at Anabolic Review Steroid Profile: Nandrolone Phenylpropionate

[Tarheel]

nice job bro! This clears alot of questions I had about NPP

[Dukkit]

not bad

though considering there is already an NPP profile on the site (as marcus showed above)

and if you use the search button... you can find many ppl whove ran it and have written about there experiences

you just reworded it all together. lol


but overall... its a nice write up bro.

[Too Little Muscles]

I have to disagree with you that NPP is painful. The ester phenylpropionate is not painful in itself. I have used NPP from a pharma that used EO oil in it and it was painless. It all depends on where you buy it. The UGL's put alot of alcohol in their product and that is probably what makes it painful. I also have to disagree with the post that said Deca was "out of style". Not so. They are exactly the same compound, Nandrolone . One has a short ester and one the long ester. They go well together. You get a higher amount quicker in your blood when you start a cycle using NPP. You only have 10 weeks and that is not a lot of time to build muscle. It takes years to build quality muscle without all the water retention. Look at the guys competing in the Mr. Olympia this year. I believe they are all in their 30's and even 40's.

[GrandmasterSpank]

I'm currently on a basic lean bulk cycle running Test Cyp @ 500mg per week, in 2 weekly injections of 1ml (My 3rd cycle). Iyo, or anyone else with experience with NPP, could I begin to incorporate it like this...

Monday: 1ml Cyp + 1 1/2ml NPP

Thursday: 1ml Cyp + 1 1/2ml NPP

Or, due to the half-life of the NPP, would is it necessary to shoot it along these lines...

Thursday: 1ml Cyp + 1ml NPP

Saturday: 1ml NPP

Monday: 1ml Cyp + 1ml NPP

...Oh, and fyi, I've never used NPP OR Deca before, so that is why I'm only intending on using a moderate 300mg dose, as opposed to the 525mg you used in your bulker example above.

[Vitruvian-Man]

Also at Anabolic Review Steroid Profile: Nandrolone Phenylpropionate

Thanks. I wrote this because obviously no one reads those profiles.

Not to mention, most people don't want to sit at home and read monotone steroid profiles written by Anthony Roberts, whose a "liar, theif, etc"... right?

I have to disagree with you that NPP is painful. The ester phenylpropionate is not painful in itself. I have used NPP from a pharma that used EO oil in it and it was painless. It all depends on where you buy it. The UGL's put alot of alcohol in their product and that is probably what makes it painful. I also have to disagree with the post that said Deca was "out of style". Not so. They are exactly the same compound, Nandrolone. One has a short ester and one the long ester. They go well together. You get a higher amount quicker in your blood when you start a cycle using NPP. You only have 10 weeks and that is not a lot of time to build muscle. It takes years to build quality muscle without all the water retention. Look at the guys competing in the Mr. Olympia this year. I believe they are all in their 30's and even 40's.

I never said deca was "going out of style...." it is one of the most popular compounds, and undeniably will always be present in the AAS world. I said.. "I believe that eventually NPP may take deca’s place," which means, in terms of popularity.

Regarding the injection pain.. perhaps that is personal. My training partners say the same thing though.

You reminded me to add something to my OP... how to stack NPP / Deca. Thanks! completely forgot about that

[Vitruvian-Man]

Thursday: 1ml Cyp + 1ml NPP

Saturday: 1ml NPP

Monday: 1ml Cyp + 1ml NPP

...Oh, and fyi, I've never used NPP OR Deca before, so that is why I'm only intending on using a moderate 300mg dose, as opposed to the 525mg you used in your bulker example above.

Ok. Well 300mg is a little low. That's basically just over a therapeutic dosage. But if you're comfortable with that, then stick to it.

IMO I would use the 2nd protocol you outlined. Injecting 3 times per week shouldn't be a problem for you, and that way you can disperse the oil into smaller, but more frequent injections.

The way I would run that cycle though is as follows:

Test-Cyp @ 0.5mL EOD
NPP @ 0.75mL EOD

^^ just shoot the cyp EOD. Generally I like to shoot my long esters each day (I know some people are reading this going WTF, why would you even bother? no added benefit??) Well shooting ED will create less peaks in blood concentrations, which in turn means less sides (for me at least). Definitely an option you could consider.

[MuscleScience]

Biological Psychology.

Specializing in psycho-active drugs and their effects on the human brain.

So then your hypothesis for your thesis is that testosterone has a psycho-thropic effect on the brain??? Possible causing either a physiological dependence or a psychological dependence

[Vitruvian-Man]

So then your hypothesis for your thesis is that testosterone has a psycho-thropic effect on the brain??? Possible causing either a physiological dependence or a psychological dependence

I'm hoping to illustrate that although testosterone is not a psycho-active drug, it can still instill a sense of psychological dependence to the actual hormone. I'm going to be viewing testosterone from the perspective of addiction, as I feel that most people get hooked on the euphoric, and invincible feeling of being on testosterone.

And BTW, I'm not looking at AAS use through a physiological dependence, because I believe there has already been too much work on the subject, Bigorexia, etc have been established by the medical community... I really want to crack into the psychological dependence... Perhaps correlate AAS use to addictive personality disorders? (I'm still in the early stages of planning! lol.)

[stpete]

Good read V-Man.

[MuscleScience]

I'm hoping to illustrate that although testosterone is not a psycho-active drug, it can still instill a sense of psychological dependence to the actual hormone. I'm going to be viewing testosterone from the perspective of addiction, as I feel that most people get hooked on the euphoric, and invincible feeling of being on testosterone.

And BTW, I'm not looking at AAS use through a physiological dependence, because I believe there has already been too much work on the subject, Bigorexia, etc have been established by the medical community... I really want to crack into the psychological dependence... Perhaps correlate AAS use to addictive personality disorders? (I'm still in the early stages of planning! lol.)

I was going to say if you were wanting to look at the physiological effect you might have a real hard time finding a unique avenue to explore, as that has been beat to hell in the literature....lol

Good Luck with your research!!!

[Vitruvian-Man]

I was going to say if you were wanting to look at the physiological effect you might have a real hard time finding a unique avenue to explore, as that has been beat to hell in the literature....lol

Good Luck with your research!!!

Thank you! I appreciate it.

[sportfan33]

wow, nice profile that was awesome!

[Swifto]

Excellent question. And thanks for the compliment bro!

I completely forgot to mention this in the OP.

You do NOT need to start NPP after you begin taking endogenous testosterone; you can begin stacking the two compounds together from the get-go.

A popular misconception with NPP is that people are scared it will shut you down TOO hard (so they believe you should run test for a couple of weeks to avoid this.) But I'll tell you that's absolutely false. You will have NO libido issues from following this protocol.

^^ However, that said, you can get libido issues while on NPP (because it does shut you down very hard.) However, in that situation, one should consider implementing proviron @ 75mg - 100mg ED (while on cycle). Otherwise, look into viagra.

I think you mean exogenous testosterone , not endogenous.

NPP (Nandrolone ) will also cause rapid HPTA shutdown, no matter what the ester.

Cycling this without a testosterone preperation may lead to testicular/erectile dysfunction in the majority of user's IMHO. I've never heard of anyone using Nandrolone with Proviron or viagra and being successful.

[lovbyts]

Also at Anabolic Review Steroid Profile: Nandrolone Phenylpropionate

I was just going to quote that one also I found in my search. LOL

OP, thanks for the write up and all the other people who jumped in with their opinions and suggestions.

[Vitruvian-Man]

I think you mean exogenous testosterone , not endogenous.

NPP (Nandrolone ) will also cause rapid HPTA shutdown, no matter what the ester.

Cycling this without a testosterone preperation may lead to testicular/erectile dysfunction in the majority of user's IMHO. I've never heard of anyone using Nandrolone with Proviron or viagra and being successful.

Oh damn... That's embarrassing! lol. Apologizes to all, I definitely meant exogenous, sorry this new spell-check auto-changes all my words into what it assumes I'm trying to say! So irritating.

Regarding the second part of your post Swifto, I believe you misinterpreted what I was saying... Or perhaps I'm not understanding you 100%.

All I was trying to convey from that point is that you do NOT need to begin taking testosterone a couple of weeks before you implement NPP or Nandrolone, for that matter, into the cycle. Nandrolone does undeniably shut the HPTA down hard... But the difference is that Deca 's ester lingers in the system for such a long time after you discontinue it's use... and that can cause problems to libido / HPTA recovery (this can even happen when you run the test two weeks past the deca, and even with an excellent PCT... I know many who have NOT recovered from deca cycles.) Whereas, the NPP will clear your system in a matter of days past stopping its use.

I was not trying to imply that one should run a NPP/Proviron /Viagra stack... LOL. You need testosterone as the base.

OP, thanks for the write up and all the other people who jumped in with their opinions and suggestions.

Not a problem. Thank you.

[RANA]

NPP and prop will be quite a nice cycle. Are you using it for a cutter, or for bulking?

Regarding the hair-loss, NPP is actually known for being quite mild compounds, in terms of speeding up male pattern baldness.

Bulk up for the fall/winter and in the spring/summer cut with tren a/prop/amst

[Swifto]

Oh damn... That's embarrassing! lol. Apologizes to all, I definitely meant exogenous, sorry this new spell-check auto-changes all my words into what it assumes I'm trying to say! So irritating.

Regarding the second part of your post Swifto, I believe you misinterpreted what I was saying... Or perhaps I'm not understanding you 100%.

All I was trying to convey from that point is that you do NOT need to begin taking testosterone a couple of weeks before you implement NPP or Nandrolone , for that matter, into the cycle. Nandrolone does undeniably shut the HPTA down hard... But the difference is that Deca 's ester lingers in the system for such a long time after you discontinue it's use... and that can cause problems to libido / HPTA recovery (this can even happen when you run the test two weeks past the deca, and even with an excellent PCT... I know many who have NOT recovered from deca cycles.) Whereas, the NPP will clear your system in a matter of days past stopping its use.

I was not trying to imply that one should run a NPP/Proviron /Viagra stack... LOL. You need testosterone as the base.



Not a problem. Thank you.

I see, I got you now.

[Swifto]

d.) Compound clears system only a couple of days after secession of use; and does not leave you terribly shut down for prolonged periods of time like deca .
e.) IMO faster recovery of the HPTA after cycle, because of ^.

I think you need to be careful with this statement. Its slightly misleading IMHO.

Nandrolone (no matter what the ester) will cause almost complete cessation of endogenous androgens, even after the first dose. It doesnt matter what ester is attached.

NPP may exit the body quicker (only a matter of days) and recovery will be equally as difficult. Their both progestins, activate the PgR and can directly act on the pituitary.

Nandrolone with Trenbolone , are the most difficult androgens to recover from, be it short or long estered of either.

I can see if you mean that you run NPP for shorter durations (because of the short ester), rather than length 10 week + cycles of Deca. So, in theory, recovery may be easier... But I dont think your above statement implies that...

[glover]

Nice write up. I have been using NPP for several years now and can attest to its benefits first hand. I made mine at 125mg/ml. It is very painless for me.

[Dr. xopholis]

Just wanted to thank you for the info. Am using Test Prop And NPP for my next cycle. I've been searching for info and yours was exactly what I needed. As a matter of fact I joined this site just to say thanks. I really appreciate the info. However, heres another question. In my past my use of Test E caused a serious case of acne. I've got another 2 months of accutane before I can start on the cycle I have planned. I was intending on using Test Prop and NPP as a bulking cycle. I noticed you had that combo in the cutting section. Can't it be used for that as well. I am turning 44 and my joints are shot. Years of contact sports have really done me in. I am looking forward to the joint benefits. By the way I have 40mls of Test Prop at 100mg/ml and 40mls of NPP at 100mg/ml. Any advice on dosages. I've done Test E, Winstrol , Sustanon , Dbol . My PCT has always been Nolva and Clomid. Thanks again for the great info.

[Vitruvian-Man]

Just wanted to thank you for the info. Am using Test Prop And NPP for my next cycle. I've been searching for info and yours was exactly what I needed. As a matter of fact I joined this site just to say thanks. I really appreciate the info. However, heres another question. In my past my use of Test E caused a serious case of acne. I've got another 2 months of accutane before I can start on the cycle I have planned. I was intending on using Test Prop and NPP as a bulking cycle. I noticed you had that combo in the cutting section. Can't it be used for that as well. I am turning 44 and my joints are shot. Years of contact sports have really done me in. I am looking forward to the joint benefits. By the way I have 40mls of Test Prop at 100mg/ml and 40mls of NPP at 100mg/ml. Any advice on dosages. I've done Test E, Winstrol, Sustanon, Dbol. My PCT has always been Nolva and Clomid. Thanks again for the great info.

First off I want to say, thanks. I really appreciate it.

Now, what I'm wondering is... why don't you start your cycle while you're still on the accutane? I find running a low dosage while on cycle is excellent for keeping the skin really dry, and clear. (unless you're running the accutane at a really high dosage currently to completely shut down oil glands for life??)

If you would like I could link you to Hazard's (another member) thread on Accutane. It's a great summary..

Anyways, you can definitely use these compounds to bulk. Not a problem..

How about something like this..

Prop (weeks 1 - 10) @ 50mg ED
NPP (weeks 1 - 8) @ 75mg ED

Adjust caloric intake to facilitate bulking. You can add an oral to help with bulking as well. (d-bol / a-drol, etc).. I would definitely suggest injecting ED, especially if you have bad joints. NPP will give you excellent lubrication, I find it really helps alleviate pain in the site of the injection. If you can't handle ED injections then EOD will be suitable.

By the way, prop is going to hurt more then anything else you've run before! you're probably going to be mighty sore for the first week or so. lol (sorry, hate to break it to you!)

[Dancer]

http://jpet.aspetjournals.org/cgi/content/full/281/1/93


Pharmacokinetics and Pharmacodynamics of Nandrolone Esters in Oil Vehicle: Effects of Ester, Injection Site and Injection Volume1
Charles F. Minto, Christopher Howe, Susan Wishart, Ann J. Conway and David J. Handelsman
Department of Anaesthesia and Pain Management, Royal North Shore Hospital (C.F.M.), and Andrology Unit, Royal Prince Alfred Hospital, Department of Medicine (C.H., S.W., A.J.C., D.J.H.), University of Sydney, Sydney, Australia


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Abstract
Introduction
Materials & Methods
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Discussion
References
We studied healthy men who underwent blood sampling for plasma nandrolone, testosterone and inhibin measurements before and for 32 days after a single i.m. injection of 100 mg of nandrolone ester in arachis oil. Twenty-three men were randomized into groups receiving nandrolone phenylpropionate (group 1, n = 7) or nandrolone decanoate (group 2, n = 6) injected into the gluteal muscle in 4 ml of arachis oil vehicle or nandrolone decanoate in 1 ml of arachis oil vehicle injected into either the gluteal (group 3, n = 5) or deltoid (group 4, n = 5) muscles. Plasma nandrolone, testosterone and inhibin concentrations were analyzed by a mixed-effects indirect response model. Plasma nandrolone concentrations were influenced (P < .001) by different esters and injection sites, with higher and earlier peaks with the phenylpropionate ester, compared with the decanoate ester. After nandrolone decanoate injection, the highest bioavailability and peak nandrolone levels were observed with the 1-ml gluteal injection. Plasma testosterone concentrations were also influenced (P < .001) by the ester and injection site, with the most rapid, but briefest, suppression being due to the phenylpropionate ester, whereas the most sustained suppression was achieved with the 1-ml gluteal injection. Plasma inhibin concentrations were also significantly influenced by injection volume and site, with the lowest nadir occurring after the nandrolone decanoate 1-ml gluteal injection. Thus, the bioavailability and physiological effects of a nandrolone ester in an oil vehicle are greatest when the ester is injected in a small (1 ml vs. 4 ml) volume and into the gluteal vs. deltoid muscle. We conclude that the side-chain ester and the injection site and volume influence the pharmacokinetics and pharmacodynamics of nandrolone esters in an oil vehicle in men.


Introduction
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Abstract
Introduction
Materials & Methods
Results
Discussion
References
For decades, administration of androgens such as testosterone and 19-nor-testosterone has been most frequently via depot i.m. injections of steroid esters dissolved in a vegetable oil vehicle (Junkman, 1957; Behre et al., 1990). Such i.m. injections provide sustained androgen release into the circulation and have remained the mainstay of androgen replacement therapy for the last few decades (Nieschlag and Behre, 1990), although the basic pharmacological mechanisms are complex and only partially understood (Zuidema et al., 1988). The basic pharmacology of this depot androgen formulation differs among species (van der Vies, 1965) but has been little studied in humans. The current understanding is that the rate-limiting mechanism governing the appearance of active steroid in the bloodstream is the retention of steroid esters from the oil vehicle depot due to oil/water partitioning, with gradual release into the extracellular fluid, where esters are rapidly hydrolyzed to liberate biologically active steroid. Other physiological and physico-chemical factors that could influence steroid appearance in the bloodstream include the chemistry of the side-chain ester (hydrophobicity, steric hindrance of hydrolysis and solubility), injection factors (depth, site and volume, pH and osmolarity of the solution), exercise and systemic illness. The influence of site and volume of injection on the release kinetics of androgen esters from oil vehicle depots has, however, not been systematically investigated in humans.

This study compared the pharmacokinetics and pharmacodynamics of two currently available esters of nandrolone, the decanoate and phenylpropionate, as well as the influence of i.m. injection sites (gluteal vs. deltoid) and injection volumes (4 ml vs. 1 ml). In addition to measuring plasma nandrolone to investigate pharmacokinetics, we measured plasma testosterone and inhibin by radioimmunoassay to determine the pharmacodynamic effects of nandrolone-induced inhibition of pituitary gonadotrophin secretion, as reflected in LH-dependent Leydig (testosterone) and FSH-dependent Sertoli (inhibin) cell function in healthy men. We analyzed these data using an indirect pharmacodynamic response model, which has demonstrated, for the first time, prominent pharmacological differences between esters differing in only a single carbon in the side-chain, as well as systematic differences attributable to injection site and volume in humans.

[Dancer]

My addy to your thread... not stepping on your foot

[Vitruvian-Man]

^^ Very cool Dancer!!

Much appreciated bro.

Love adding new additions to the thread

[Dancer]

Keep up the good work bro... there is always room for newer members stepping up.