
Originally Posted by
600@50
I can tell you for a fact that after over 24 years of TRT and blasting and cruising that if I up the dosages I get a response with increased size and strength. Is there a desensitizing of receptors after this prolonged exposure? Maybe. I can't say for sure or by how much. Your body will over time go back to the size and strength being dictated by the hormone level that is either naturally being produced or is exogenously being produced. Look at all the bodybuilders that retire and still train. Every single one of them shinks down to whatever hormone they have. Presumably all are on TRT at that phase of life. As far as the same dosages yielding the same amount of gains, that's not going to happen the further you get past your genetic limit. The further past you get in size and strength the higher the dosages it will take to gain. This is why it is so important to have diet, training, sleep and rest dialed in as best you can because to force your body to go where it doesn't want to go is not an easy task and not for everyone.