
Originally Posted by
walkfast
Athletes have used various methods before drug testing to either decrease the excretion of banned drugs or prevent the detection of these drugs in the urine. Compounds that have been used to decrease the excretion of unblock steroids and their metabolites include uricosuric agents (e.g., probenecid, carinamide, sulfinpyrazone, phenylbutazone, benzbromarone), corticosteroids, estrogens, oral contraceptives (containing norethindrone), Depo-Provera, phenytoin, pyrazinamide, dexamethasone, and apple cider vinegar. Compounds used to prevent the detection of banned drugs in the urine include various diuretics, Defend, and chemical contaminants such as sodium hypochlorite, and bacteria. Defend acts by both decreasing the excretion of the drug and by diluting the the urine (Di Pasquale, 1992a).
Case studies have been used to study drug detection techniques on athletes who self-administered anabolic-androgenic steroids (de Boer, De Jong, van Rossum, & Maes, 1991).