
Originally Posted by
Deep_Fried
DAC is the "Drug Affinity Complex".
Real CJC-1295 is called DAC-GRF or DAC-GHRH. The DAC is basically a complex of lysine/maleimodopropionic acid that is linked to the 29th position of GRF 1-29. This allows it to bind to albumin and extend the halflife to 5-8 days.
GRF 1-29 without the DAC is just a tetrasubstituted version of plain GRF 1-29 sometimes refered to as modified CJC.
Modified CJC or Dac-less CJC is just TSubed GRF 1-29(4 amino substitutions) . Halflife is about a couple of hours and needs to be dosed multiple times per day.
Sermorelin or plain GRF 1-29 without the 4 amino substitutions has a life of a few minutes and is the least effective GHRH analog.
Note: Most CJC is in fact tetrasubstituted GRF 1-29. The reason is that many peptide synthesizers cannot make the DAC as it is synthesized seperately outside the scope of standard solid or liquid phase peptide synthesizers. Many sources do not have access to this and pass off the final product as CJC to their distributors.
Best way to check for the real CJC is to see a COA depicting the complete compound, especially the Lysine/MPA complex. Still, Tsubed GRF has been passed off with COAs depicting CJC, so the final bet is to make note of the molecular weight.
GHRH Molecular Weights:
CJC-1295 is about 3647.17 **
Lysine + the DAC alone is about 280.29 **
Modified or tetra-substituted GRF(1-29) is about 3366.88 +/- 2
Unmodified GRF(1-29) or Sermorelin is about 3357.9