Blood work-plz review and comment

[w8liftr]

I'm 49; been on trt for 2 1/2 years - Test Cyp 200 mg e2w. last November convinced doc to up to 400 MG e2w and injected 200 e7d. Doc wanted me to see endo to get their "blessing" on this amount. No ai or hcg. I saw endo on 4/8/2013 and got blood drawn on 4/9. Things to note are the high PSA. Because of this the endo recommended I immediately cease trt and see urologist (after getting second PSA test to confirm it's high). Also note the high total estrogen and above average estradiol. Upping test cyp to 400 mg e2w was a mistake as it aromatized to estrogen.

So now I'm in the position of ceasing trt, getting the high psa analyzed with possible prostate biopsies, and who knows what then. Been feeling tired, fatigued last few months, probably from high estrogen.
Strength is down probably because I lowered test cyp to a little less than 100 mg e7d and will half that until I run out end of this month, and then it's no trt and not restart protocol after that, unless of course the high psa was false and urologist confirms healty prostate. Fatigue probably also due to elevated estrogen.

Below are recent blood work #'s from last April and again last week (more thorough).
Please review my blood work and provide thoughts, comments, especially as regards T, free-bioaval T, Estr., and low IGFBP-3, low normal pregnenalone, and low normal DHEA. THANKS!

*** FROM 6/3/2013 ***


TEST MY NUMBER REF RANGE

ACTH 35.7 7.2 - 63.3 pg/mL

Testosterone 316 ng/dL (while on 400 mg e2w! - converting to estr?)
Males:
20-49 yrs 72-853

Estradiol 43 pg/mL
Males: 20-56

Sex Hormone Binding 23.5 16.5 - 55.9 nmol/L

issam-ch web site complutes free and bioavailable t as follows:
Free Testosterone 7.33 ng/dL = 2.32 %
Bioavailable Testosterone 179 ng/dL = 56.8 %

PSA 7.7 0.0 - 4.0 ng/mL HIGH

Vit D, 25-Hydroxy 29.7 30.0 - 100 ng/mL LOW

Somatomedin (IGF-I) 179 59 - 201 ng/mL

IGF Binding Protein-3 3.6 3.3 - 6.7 mg/L

LH <0.1 MIU/mL Males: 0.8-7.6 LOW?

FSH 0.1 MIU/mL Males: 0.7-11.1 LOW?

Vitamin B-12 760 239 - 931 pg/mL

Thyroid Peroxidase Ab <6 0 - 34 IU/mL

Thyroglobulin Ab <20 0 - 40 IU/mL
Siemens (DPC) ICMA Methodology

Thyroglobulin Ab <20 0 - 40 IU/mL
Siemens (DPC) ICMA Methodology

Magnesium 2.2 1.5 - 2.5 mg/dL

Prolactin 7.6 2.5 - 17.0 ng/mL

Cortisol 13 5 - 25 ug/dL

Cholesterol, Total 162 0 - 200 mg/dL
Triglycerides 263 10 - 150 mg/dL HIGH
HDL 40 30 - 60 mg/dL

Sodium 137 135 - 146 mmol/L
Potassium 4.2 3.5 - 5.3 mmol/L
Chloride 102 98 - 110 mmol/L
CO2 24 21 - 33 mmol/L
Anion Gap 11 3 - 16 mmol/L
BUN 10 7 - 25 mg/dL
Creatinine 0.99 0.50 - 1.30 mg/dL
Glucose 83 65 - 99 mg/dL
Calcium 9.2 8.6 - 10.2 mg/dL
Total Bilirubin 1.0 0.2 - 1.2 mg/dL
AST 28 17 - 59 U/L
ALT 36 9 - 60 U/L
Alkaline Phosphatase 59 40 - 115 U/L
Total Protein 7.3 6.2 - 8.3 g/dL
Albumin 4.5 3.6 - 5.1 g/dL
GFR MDRD Af Amer 97 See note.

WBC 7.1 3.8 - 10.8 10E3/uL
RBC 5.62 4.20 - 5.80 10E6/uL
Hemoglobin 15.3 13.2 - 17.1 g/dL
Hematocrit 46.6 38.5 - 50.0 %
MCV 82.9 80.0 - 100.0 fL
MCH 27.3 27.0 - 33.0 pg
MCHC 32.9 32.0 - 36.0 g/dL
RDW 14.3 11.0 - 15.0 %
Platelets 164 140 - 400 10E3/uL
MPV 6.8 7.5 - 11.5 fL


*** BLOOD WORK FROM 4-9-2013 ***

Testosterone 683 ng/dL
Adult Male Ranges:
20-49 years 270-1194 ng/dL

Estrogens, Total 121 40 - 115 pg/mL HIGH, but not the sensitive test

Pregnenolone, LC/MS/MS 41 13 - 208 ng/dL

DHEA 75 31 - 701 ng/dL

Iron 82 45 - 170 ug/dL
% Iron Saturation 20.0 15.0 - 55.0 %
TIBC 421 261 - 462 ug/dL

Ferritin 13.7 18.0 - 464.0 ng/mL

Cholesterol, Total 182 0 - 200 mg/dL
Triglycerides 259 10 - 150 mg/dL HIGH
HDL 45 30 - 60 mg/dL

TSH 2.03 0.45 - 4.50 mIU/L

Free T4 1.08 0.61 - 1.76 ng/dL

T3, Free 4.7 2.8 - 5.3 pg/mL

[Spartans09]

Hopefully they can quickly rule out any serious problem with the prostate. Coming off is necessary to see if the psa score comes down and is testosterone related. Having to come off after a couple of years with no restart protocol is going to be rough unfortunately.
If they are able to rule out trouble With the prostate you really need better professional help with your trt as you go back on. Every two week dosing of cyp is awful(like a roller coaster ride) and 200 mg/ week in all likelihood is way too much. Additionally, you need to take an aromatase inhibitor to control estrogen.
I also take 50mg of micronized dhea and pregnenolone.

[kelkel]

Good advice by Spartans. Find another doc as this guy is clueless and will hurt you. When was blood pulled relative to your injection? Also, remember testosterone does not cause prostate cancer but can exacerbate it if it already exists. A high psa level is not always indicative of a serious issue but it obviously needs to be looked into. Get it tested again and refrain from ejaculation for a few days prior as well.

[w8liftr]

Second psa test 2 days after came in at 6.6, down from 7.7, so that's good. Urologist did dre, seemed ok to him. Prescribed Cipro for 5 days to rule out infection and will test psa again next week. If not lower will do biopsy. If no cancer cells I wonder if they will put me back on trt as long as psa doesn't go up but is still over 4? Right now taking otc prostate health supps like saw p. lycopene etc. if I do go back on trt I will ask for .50 to .75 mg test cyp every 4 or 5 days.

[kelkel]

Keep informed on the outcome in this thread.

Good luck w8.

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