Peptides question

[sleepstalker]

Personally I am not a fan of IGF, GH or insulin. BUT is the muscle growing effect of test due to the actions of IGF? Meaning in the body does test ultimately cause muscle recovery/growth due to its actions of IGF on the muscle? Again not a fan of peptides as it wasn't used in the golden era and I wouldn't want to risk growth of the internal organs.

[GearHeaded]

no the muscle growing effects of testosterone are not just directly tied to IGF . though there are some indirect connections. Testosterone converts to estrogen, and estrogen increases both HGH and IGF levels in the body (which both promote growth). so yes in a way Test promotes IGF.

but test itself directly communicates DNA to muscle cells via the androgen receptor . telling the cells things like to up regulate protein synthesis. as well as things outside the androgen receptor like nitrogen retention. all things which help build muscle.

IGF is just one growth factor out of many.

[GearHeaded]

Again not a fan of peptides as it wasn't used in the golden era .

side point here -- lots of things were not used in the golden era. but this is one , out of many, reasons why none of the golden era guys would probably even place top 3 at a non pro national level npc show today. they simply never got lean enough.

[fitguy]

side point here -- lots of things were not used in the golden era. but this is one , out of many, reasons why none of the golden era guys would probably even place top 3 at a non pro national level npc show today. they simply never got lean enough.

Can you please give me an idea about expectations,sides,good sources etc of peptides?

[HoldMyBeer]

side point here -- lots of things were not used in the golden era. but this is one , out of many, reasons why none of the golden era guys would probably even place top 3 at a non pro national level npc show today. they simply never got lean enough.

I see what you mean and agree. But I think Lou Ferrigno in Arnold SHOULD end up top 3 because I think Arnold's point of everything being about size/leaness/hardness these days and forgetting about symmetry and aesthetics is true. Which is a shame.
that being said, if they made another category where was JUST the biggest f****** dude wins, that would be awesome.

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[fiddlesticks]

most anabolic action of steroids end up mediated by IGF itself - yes, it would be near impossible to gain muscle with igf being low or unresponsive.

IGF also has enormous fat loss potential so as far as getting lean goes any substance that increases IGF will end up assisting fat loss assuming other factors are in play - hypocaloric diet + IGF + stimulant (clen/albuterol) + weights = massive results.

the strongest peptide is hexarelin , it will increase GH and IGF a very good amount but also will build a tolerance.

[GearHeaded]

most anabolic action of steroids end up mediated by IGF itself .

I don't think this is true (as a blanket statement at least).

we all know that Deca is an awesome muscle builder. its been used to build physiques for decades. however studies have been done that show that Deca does NOT increase IGF levels at all. So deca's anabolic action is not "mediated by IGF itself".

now studies have been done that do show Testosterone supplementation resulted in an increase in IGF levels. but whats interesting here is that there was also a very big increase in estrogen in these studies. And estrogen does directly increase IGF.
when looking at the Deca study there was NOT an observed increase in estrogen (interesting that when there was not an increase in estrogen there was not an increase in IGF ).

you would think that Deca, being more anabolic then test, would have led to an increase in IGF. but nope, it was test because of its aromatization into estrogen that led to an increase in IGF. probably a reason why wet compounds are also better for putting on size.

but the point is still that NO, steroids anabolic action does not end up being mediated by IGF itself at all . Anabolic actions do NOT require an increase in IGF and steroids work just great without increasing IGF (however, an increase in IGF is still a big 'perk' that some steroids cycles can help amplify)

[GearHeaded]

Personally I am not a fan of IGF, GH or insulin. .

really your not a fan ? well then you may want to have your pancreas and pituitary gland cut out of your body because your body is constantly producing these in abundance.

[fitguy]

most anabolic action of steroids end up mediated by IGF itself - yes, it would be near impossible to gain muscle with igf being low or unresponsive.

IGF also has enormous fat loss potential so as far as getting lean goes any substance that increases IGF will end up assisting fat loss assuming other factors are in play - hypocaloric diet + IGF + stimulant (clen/albuterol) + weights = massive results.

the strongest peptide is hexarelin , it will increase GH and IGF a very good amount but also will build a tolerance.

What to expect from hexarelin and how long is it usually run for?

[GearHeaded]

Hex will illicit the most prominent natural pushes of GH. however you de-sensitize to it rather quickly so about 4 weeks is the most you'll run it for. SO you'll need to stack it with other secretagogues/peptides in order to get long term benefits of natural GH release

[fitguy]

Hex will illicit the most prominent natural pushes of GH. however you de-sensitize to it rather quickly so about 4 weeks is the most you'll run it for. SO you'll need to stack it with other secretagogues/peptides in order to get long term benefits of natural GH release

Will it produce anything on its own in 4 weeks?

[fiddlesticks]

hex + high doses of arginine is a very very potent combination.

[GearHeaded]

Will it produce anything on its own in 4 weeks?

it will produce an elevation in natural growth hormone levels, and thus some lipolytic effects , which should result in some fat loss if your diet is on point and in a deficit

[fitguy]

it will produce an elevation in natural growth hormone levels, and thus some lipolytic effects , which should result in some fat loss if your diet is on point and in a deficit

What about sides what to expect as well as muscle gain

[GearHeaded]

What about sides what to expect as well as muscle gain

the side effects are the same as would be with HGH itself..

muscle gain will be minimal and likely un-noticeable. unless running multiple peptides over a long duration of time where IGF levels remain in a constantly elevated state and things like satellite cell proliferation and hyperplasia take place ,, so that new muscle 'tissue' is there to eventually be hypertrophied and then become noticeable.

so the muscle gains for the first 8 months or so are at the cellular level and won't be seen with the naked eye. its a long term investment.
of course the process can be sped up with combining insulin and AAS.

the lipolytic effects are more noticeable in the short term however.

[fitguy]

the side effects are the same as would be with HGH itself..

muscle gain will be minimal and likely un-noticeable. unless running multiple peptides over a long duration of time where IGF levels remain in a constantly elevated state and things like satellite cell proliferation and hyperplasia take place ,, so that new muscle 'tissue' is there to eventually be hypertrophied and then become noticeable.

so the muscle gains for the first 8 months or so are at the cellular level and won't be seen with the naked eye. its a long term investment.
of course the process can be sped up with combining insulin and AAS.

the lipolytic effects are more noticeable in the short term however.

Is there any particular company that you recommend?

[GearHeaded]

I've had good luck with Euro Pharmacies peptides based out of Turkey