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Thread: gyno from trt

  1. #1

    gyno from trt

    Ok so I think I may have some gyno developing from my trt. Left nipple has a nodule underneath it, and it is a little sore. I was really sore last week, but some of that might have been me pressing on it trying to see if it was indeed a knot or swollen.

    I had labs drawn Friday morning and will get results back mid week coming up. I have a-dex on hand if my estrogen is high.

    Wondering about dose though. I think they're 1mg tabs. Thinking one tablet a day? or eod?

  2. #2
    Not sure but if gyno is already developing shouldnt you start the counter-measure pills right away not wait for blood work? I have not had gyno myself but i know there are some pills that should help get rid of it but i think you gotta take them straight away later might be too late already?

  3. #3
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    Are you SURE this is gyno? It can be hard to tell sometimes.

    Nolvadex, 10 to 20mg per day for the first couple of weeks, 5 to 10mg per day for subsequent weeks until it is gone. I think you would be fine at the lower dose, but it does depend on how you respond, etc. You might also try raloxifene, peep google or this site for doses on that. Both SERMs are generally "safe" to run for several weeks at a time.... They are not without potential sides, but better than running around with gyno.

    You can also try adding certain AAS, like proviron (has some AI qualities), masteron or primo. Both mast and primo can serve AI duties, and masteron will do a good job of binding to the receptors in the breast to help reduce gyno. Note that all of those are DHT's, so maybe don't try them all at once, if they are new to you and you value your hairline and / or prostate.

    Your estrogen is likely not too high, depending on what your TRT dose is. I would not commence to nuking it with 1mg adex daily, EOD, or even twice a week, UNLESS you are absolutely positive that you have gyno and it is estrogen based.

  4. #4
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    Real TRT will not give you Gyno, if you are developing Gyno it already existed from childhood and the TRT is exacerbating it. What is your TRT dose, how often do you administer the dose, every two weeks, every week twice a week, other?

    Arimidex should be taken as little as possible and the lowest dose possible. I would take it at no more than 0.5mg 24 hours after your injection only. As stated above get on Nolvadex now, run it at 20mg twice a day for a week, if symptoms subside you can drop it to 10mg a day.

    If you don't have nolvadex on hand then I would run Arimidex a bit high for one week, so 0.5mg EOD (every other day), you should feel relief very fast on this dose if you do not I would run it at the same dose every day until symptoms subside. Never take your time dealing with gyno, kick it's ass right away.

  5. #5
    No I'm not really sure this is gyno. Which is why I wanted to see my estrogen levels before taking anything else.

    I will say, the soreness has been there for around a year. Started out as just my left nibble feeling a little weird and sore. I was on thengel for about 3 years until about 7 weeks ago I started injections. But the last couple weeks it got more sore. Like I said. Maybe some soreness from me pressing and feeling around in what I think is a knot. But I also feel a knot in the ride side as well but it's not sore and maybe a little smaller.

    I'm doing 200mg once a week of prescribed test, so yes it's real test.

    Again, I have 1mg Alex tabs on hand. Don't have any Nolvadex, since this started as just trt, not a blast.

    If my estrogen isn't high when I go back, I'll get an appointment with my pcp for the issue.
    Last edited by teedoff; 05-29-2022 at 09:42 AM.

  6. #6
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    Quote Originally Posted by teedoff View Post
    No I'm not really sure this is gyno. Which is why I wanted to see my estrogen levels before taking anything else.

    I will say, the soreness has been there for around a year. Started out as just my left nibble feeling a little weird and sore. I was on thengel for about 3 years until about 7 weeks ago I started injections. But the last couple weeks it got more sore. Like I said. Maybe some soreness from me pressing and feeling around in what I think is a knot. But I also feel a knot in the ride side as well but it's not sore and maybe a little smaller.

    I'm doing 200mg once a week of prescribed test, so yes it's real test.

    Again, I have 1mg Alex tabs on hand. Don't have any Nolvadex, since this started as just trt, not a blast.

    If my estrogen isn't high when I go back, I'll get an appointment with my pcp for the issue.
    In this case, I like where I think @Iranon was going: maybe break that dose into smaller more frequent doses to level out the peaks and valleys of hormonal fluctuation that can cause more signficant sides. Not speaking for @Iranon, I just believe that is a good strategy and probably where he was headed, too.

    Since you have only been on injections for 7 weeks I'm guessing you haven't pulled bloods yet. 200mg is a pretty big TRT dose, so you might benefit from coming down on it, in addition to 2 or even 3x a week injections.

    Be advised, and you may know this already, that most PCPs are almost clueless on TRT and issues beyond "dur, inject some test until bloodwork not show red numbers". In other words, I think we have covered the bases here pretty well regarding TRT issues, though there is a slim chance maybe something else is going on. And we are just making educated guesses here, without bloods it is tough to say what is what definitively.

  7. #7
    Quote Originally Posted by Cylon357 View Post
    In this case, I like where I think @Iranon was going: maybe break that dose into smaller more frequent doses to level out the peaks and valleys of hormonal fluctuation that can cause more signficant sides. Not speaking for @Iranon, I just believe that is a good strategy and probably where he was headed, too.

    Since you have only been on injections for 7 weeks I'm guessing you haven't pulled bloods yet. 200mg is a pretty big TRT dose, so you might benefit from coming down on it, in addition to 2 or even 3x a week injections.

    Be advised, and you may know this already, that most PCPs are almost clueless on TRT and issues beyond "dur, inject some test until bloodwork not show red numbers". In other words, I think we have covered the bases here pretty well regarding TRT issues, though there is a slim chance maybe something else is going on. And we are just making educated guesses here, without bloods it is tough to say what is what definitively.
    So perhaps my dose is a bit high. My hormones guy prescribed me 150mg a week. The vials I got are 200mg 1ml ampules. I didn't think it would hurt using all of it and not wasting those last 50mg lol.

    Like I said, I'll know more with my follow up this week.

  8. #8
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    Quote Originally Posted by teedoff View Post
    So perhaps my dose is a bit high. My hormones guy prescribed me 150mg a week. The vials I got are 200mg 1ml ampules. I didn't think it would hurt using all of it and not wasting those last 50mg lol.

    Like I said, I'll know more with my follow up this week.
    To avoid waste with amps, you can draw with a filtered syringe, then back fill the appropriate number of slin pins. Store those and use over the course of the next week or so. I think you are good as long as there is a little air between the plunger and the oil.

  9. #9
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    You could also transfer from amps to a sterile vial if you want. If you store in pins, dig around for particulars on how and where. I've not done it myself, but know that it is a frequent practice.

  10. #10
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    Last year before my gyno surgery I had to use an AI because even 120mg test once a week gave me more gyno sides, I broke up the dose to 60mg twice a week (Monday & Friday) my sides disappeared.

  11. #11
    Thanks for all the tips and advice. As said, I'm not positive this is gyno. It was mildly present when I was on the gel. Can't remember specifically when I started noticing it while on the gel, but at the one pump a day, which I think is 20mg or so a pump, I wqs still having the mild soreness in one side. Never the other side either.

    So for my trt dose, I'll ask about the vials instead of the amounts. When I get to a good place to do some blasts, I'll buy those online and keep my prescribed stuff as my maintainence stock.
    Last edited by teedoff; 05-29-2022 at 02:38 PM.

  12. #12
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    Mine just came in/out for years upon years - but, I ran heavy cycles. I always used Nolvadex to knock it down, letro once - then suddenly, the Dex stopped working. These ugly bastards straight grew like no other - even when I pulled my doses down & cranked up the Dex


    Had em chopped out, even then they tried to come back for just a bit. My surgeon put me on Nolvadex & it knocked it down - now, they are finally completely gone - gawd, that chest pain/feeling sucked

  13. #13
    Ok as promise. Here are my labs from last week.

    My estrogen might be a touch high. Lol
    Click image for larger version. 

Name:	20220602_113640.jpg 
Views:	82 
Size:	1.01 MB 
ID:	181875
    Last edited by almostgone; 06-02-2022 at 12:46 PM.

  14. #14
    Quote Originally Posted by Iranon View Post
    Last year before my gyno surgery I had to use an AI because even 120mg test once a week gave me more gyno sides, I broke up the dose to 60mg twice a week (Monday & Friday) my sides disappeared.
    So yeah my PA suggested breaking mine into two weekly doses and as shown in the image, he also said I could take 1mg tab adex twice a week for one week then one tab a week and see if my symptoms went away. He said I should still have it checked out in case it wasn't gyno.

  15. #15
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    Quote Originally Posted by teedoff View Post
    Ok as promise. Here are my labs from last week.

    My estrogen might be a touch high.
    LolAttachment 181874

    Your labs aren’t out of control by any means. I’m prescribed 200 mgs a week and my total test comes in right at 1000, my free is mid 20’s and estrogen is around 30. Hard to paint with a broad brush.

    Definitely follow up with a gyno exam before you go and crush your estrogen. I do fine until I cross 100 and then deal with edema and moon face (no gyno though).

    Lastly, you should delete that lab report you posted…edit your personal info and the repost it. No need to have your personal information posted on the web, ya know?

  16. #16
    Quote Originally Posted by SampsonandDelilah View Post
    Your labs aren’t out of control by any means. I’m prescribed 200 mgs a week and my total test comes in right at 1000, my free is mid 20’s and estrogen is around 30. Hard to paint with a broad brush.

    Definitely follow up with a gyno exam before you go and crush your estrogen. I do fine until I cross 100 and then deal with edema and moon face (no gyno though).

    Lastly, you should delete that lab report you posted…edit your personal info and the repost it. No need to have your personal information posted on the web, ya know?
    Ah crap! I meant to redact that stuff before posting. Lol. I'll change it. Thanks.

  17. #17
    Well I deleted, I thought, the old one and added the new one. Now both are showing. The text editing UI is terrible on this site.

    Can a moderator remove them? Maybe im doing something wrong.

  18. #18
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    You’re not the first by any means…one of the moderators can help you I’m sure. Maybe send a PM to Booz and Almost Gone, they’re on top of everything if they’re not busy. I’m sure they can help

  19. #19
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    Quote Originally Posted by teedoff View Post
    Ok as promise. Here are my labs from last week.

    My estrogen might be a touch high. Lol
    Click image for larger version. 

Name:	20220602_113640.jpg 
Views:	82 
Size:	1.01 MB 
ID:	181875
    Think I nuked the right labwork.
    There are 3 loves in my life: my wife, my English mastiffs, and my weightlifting....Man, my wife gets really pissed when I get the 3 confused...
    A minimum of 100 posts and 45 days membership required for source checks. Source checks are performed at my discretion.

  20. #20
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    Quote Originally Posted by almostgone View Post
    Think I nuked the right labwork.

    You did.

    As usual…AG to the rescue

  21. #21
    Thanks man!

  22. #22
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    Quote Originally Posted by teedoff View Post
    Ok as promise. Here are my labs from last week.

    My estrogen might be a touch high. Lol
    Click image for larger version. 

Name:	20220602_113640.jpg 
Views:	82 
Size:	1.01 MB 
ID:	181875


    For what it's worth, I would drop back to .3cc (~66mg) of cyp twice per week, stash back the anastrozole, and filter the extra test in the amps into a pre-sealed sterile vial. It will be a pain, but use a 23 guage or smaller. A larger needle will chew up the stopper unless you can get the with silicone septums.

    However, that's between you and your Dr. It might be better to stick with his plan and later on down the road, perhaps try what's been suggested.

    I know it doesn't sound like much, but over time it will add up. That way you eventually have a little extra on hand to do whatever with.
    Believe it or not, the pharmacies occasionally run out of testosterone and it's a royal pain to transfer a script to another pharmacy. Things happen like the refills on the script get lost, etc.
    There are 3 loves in my life: my wife, my English mastiffs, and my weightlifting....Man, my wife gets really pissed when I get the 3 confused...
    A minimum of 100 posts and 45 days membership required for source checks. Source checks are performed at my discretion.

  23. #23
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    One other thing. Make sure your blood are pulled on a trough day,/ just prior to your injection.
    There are 3 loves in my life: my wife, my English mastiffs, and my weightlifting....Man, my wife gets really pissed when I get the 3 confused...
    A minimum of 100 posts and 45 days membership required for source checks. Source checks are performed at my discretion.

  24. #24
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    Quote Originally Posted by SampsonandDelilah View Post
    You did.

    As usual…AG to the rescue
    Ah, I just happened to wander through. I'm old and I fart dust.
    There are 3 loves in my life: my wife, my English mastiffs, and my weightlifting....Man, my wife gets really pissed when I get the 3 confused...
    A minimum of 100 posts and 45 days membership required for source checks. Source checks are performed at my discretion.

  25. #25
    Quote Originally Posted by almostgone View Post
    For what it's worth, I would drop back to .3cc (~66mg) of cyp twice per week, stash back the anastrozole, and filter the extra test in the amps into a pre-sealed sterile vial. It will be a pain, but use a 23 guage or smaller. A larger needle will chew up the stopper unless you can get the with silicone septums.

    However, that's between you and your Dr. It might be better to stick with his plan and later on down the road, perhaps try what's been suggested.

    I know it doesn't sound like much, but over time it will add up. That way you eventually have a little extra on hand to do whatever with.
    Believe it or not, the pharmacies occasionally run out of testosterone and it's a royal pain to transfer a script to another pharmacy. Things happen like the refills on the script get lost, etc.
    Thanks. I'm new to injecting myself so I'll have to research this process as I'm unfamiliar.

    Also, yes I pin on Fridays and my labs were pulled early Friday morning last week before my injection.

  26. #26
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    Filtering isn't bad. I prefer a .22 micron PVDF syringe filter. You can usually pick up a 10 pack on Amazon.
    Someone will walk you through it if you decide to go that route.
    I definitely recommend pre-sealed vials with a silicon septum. They "heal" up from repeated needle punctures.


    Edit: On second thought you may want to accumulate 10ml worth into a vial and then filter that quantity into another pre-sealed vial.. That will be cheaper and cut down on needle punctures.
    Last edited by almostgone; 06-02-2022 at 02:31 PM.
    There are 3 loves in my life: my wife, my English mastiffs, and my weightlifting....Man, my wife gets really pissed when I get the 3 confused...
    A minimum of 100 posts and 45 days membership required for source checks. Source checks are performed at my discretion.

  27. #27
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    That’s right where I keep my e2 - can’t be good for me, but keeps me horny af & now I have no bitch tits to tell me different

  28. #28
    I’m on trt 200mg test cyp a week. I’m prone to gyno even though adex is mixed in with my dose. I have a little nolva I keep on hand, when the nips start feeling a little sore I can take like 10 mg a day for 3 days and it gets it back under control and may not feel sensitive again for 2-3 weeks. Very easy to manage. Still, next big work bonus I think I’m pulling the trigger to get some old puberty gyno removed along with the glands so I don’t have to worry about this crap anymore lol

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