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Thread: who here has tried durasteride for hairloss and liked it?

  1. #1
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    who here has tried durasteride for hairloss and liked it?

    Who here has tried it for hairloss and liked the results? And is this something that can be obtained through a prescription from the dermatologist or by other means? thanks for info..propecia is not getting the job done right now...

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    i am on durasteride, i am taking 500mg/week test cyp..i am not worring about hair, am taking because prostate problem...try durasteride from AR, i think only way to get script for durasteride if have prostate problem, eventhough its hard to get script for durasteride, most insurance will prescribe you with propecia, if your hair is falling out then its mean you have high DHT lever and will cause prostate enlargment over time, how much propecia are you taking , if you taking 1mg day and helping try 2 or 3 mg aday that will cost some money...try durasteride from ad banner from top, i heard it good

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    are you on any cycle?

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    Quote Originally Posted by davidboy
    are you on any cycle?
    thanks for info, yea long story short...I stopped test based cycles a while ago when I realized my hair was falling out. I experimented with some anavar, and everything seemed pretty good. For a year or so I have seen little or no shedding at all with anavar. But a few months ago, the doctore prescribed me Medrol, which is a corticosteroid to reduce inflammation in my tonsils so I wouldn't have to have an operation. Well, anything is better than that horrible operation, and took it. later I found out that it was testosterone and progesterone based, or a derivitive of them. A week before I started the anavar cycle, I started shedding like a dog. now I am on week 5 of the cycle, but I know it is not the anavar, it has to be the Medrol. But of course, I'm sure that anavar probably isn't helping the situation. I started taking 80mgs /day of the var, now i cut it back to 40mgs/day. I am also taking t3 and clen. Again, with anavar I havent seen much hairloss, but damn, now its bad.

    I guess i'll be hitting dura, prope, rogain, nizoral, .......

  5. #5
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    Quote Originally Posted by str8cubano79
    yea long story short..
    woops...

  6. #6
    Why do you think that the finasteride isn't doing the trick? If it's because you're still experiencing shedding while using finasteride, then you have nothing to worry about. THIS IS NORMAL.

    Review the following thread:
    http://forums.steroid.com/showthread...eride+shedding

  7. #7
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    Quote Originally Posted by MoneyAddyct
    Why do you think that the finasteride isn't doing the trick? If it's because you're still experiencing shedding while using finasteride, then you have nothing to worry about. THIS IS NORMAL.

    Review the following thread:
    http://forums.steroid.com/showthread...eride+shedding
    I have been using propecia for over a year now. Not the normal shedding in the beggining

  8. #8
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    I started using Dutasteride about 7 months ago at .5mg every day, and im not that prone to hairloss...maybe a 3 out of 10 (10 being the worst), and within 2 wks my small signs of shedding halted completely, im on the stuff year round from now on, till im done cycling...it really works, and helps keeping the prostate down too while using test products....

  9. #9
    duta duta duta

  10. #10
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    yup...I'm a big fan of Duta....got my Dr. to get me a script of Avodart (off label) specifically due to hair loss. Noticed no more hair loss once going on, and if anything maybe even a little thicker. Side note: spoke to a pharm rep of the product and found that it has a fairly long half life...I didn't like the idea of "possibly" reducing wanted effects of various suppliments and thus cut back from the .5/day to .5 about every third day. Noticed no reduction in effectiveness. Lastly, I notice a serious reduction in acne...so for those of you with this problem it may be a two fold solution.

  11. #11
    Quote Originally Posted by Scoobs
    yup...I'm a big fan of Duta....got my Dr. to get me a script of Avodart (off label) specifically due to hair loss. Noticed no more hair loss once going on, and if anything maybe even a little thicker. Side note: spoke to a pharm rep of the product and found that it has a fairly long half life...I didn't like the idea of "possibly" reducing wanted effects of various suppliments and thus cut back from the .5/day to .5 about every third day. Noticed no reduction in effectiveness. Lastly, I notice a serious reduction in acne...so for those of you with this problem it may be a two fold solution.


    sure!

    10-14-2005.
    http://forums.steroid.com/showthread.php?t=200188
    Dutasteride

    there is two 5 ar isoenzymes,dutasteride block both ,
    finasteride just block type 2 (scalp tissue).
    acne is type 1 .

    5 alpha-Reductase Isoenzyme Inhibition
    Both dutasteide and finasteride are 4-azasteroid inhibitors of 5 a -reductase , the enzyme responsible for converting testosterone to dihydrotestosterone (DHT) in the prostate. DHT is the primary androgen int the prostate and has a major role in the development and progression of benign prostatic hyperplasia (BPH) and other prostate diseases (1,2,3,4) as well as androgenetic alopecia (5,6).

    Two isoenzymes of 5 a -reductase exist (type 1 and type 2). Type 2 is the dominant isoenzyme in genital tissues including the prostate, but is also present in the skin and liver. Type "1" 5 a -reductase is also found in the skin, liver and prostate, and is the dominant form in sebaceous glands. (1,2,4).
    Finasteride is a competitive inhibitor of 5 a -reductase that selectively inhibits the type 2 isoenzyme, with which it forms a stable enzyme complex. this selective activity is attributed to a much lower affinity for the type 1 isoenzyme, and thus a slow rate of type 1 isoenzyme inhibition. In contrast, dutasteride is a competitive inhibitor of both forms of the enzyme, with 45-fold greater potency than finasteride against type 1 and type 2 isoenzymes at clinically used doses. this dual inhibition may potentially be beneficial in prostatic diseased that depend on androgens, since both isoenzymes are up-regulated in BPH while only the type 1 isoenzyme is up-regulated in prostate cancer, as noted above (2,1).



    Pharmacogenetic analysis of human steroid 5 alpha reductase type II: comparison of finasteride and dutasteride.
    Makridakis N, Reichardt JK.
    J Mol Endocrinol. 2005 Jun;34(3):617-23.

    An update on the use of 5 alpha-reductase inhibitors.
    Foley CL, Bott SR, Shergill IS, Kirby RS.
    Drugs Today (Barc). 2004 Mar;40(3):213-23. Review.

    Steroid Biochem Mol Biol. 2004 Jan;88(1):1-16.


    Selective non-steroidal inhibitors of 5 alpha-reductase type 1.

    Occhiato EG, Guarna A, Danza G, Serio M.

    Dipartimento di Chimica Organica Ugo Schiff, Polo Scientifico Universita di Firenze, Via Della Lastruccia 13, I-50019 Sesto Fiorentino, Florence, Italy.

    The enzyme 5 alpha-reductase (5 alpha R) catalyses the reduction of testosterone (T) into the more potent androgen dihydrotestosterone (DHT). The abnormal production of DHT is associated to pathologies of the main target organs of this hormone: the prostate and the skin. Benign prostatic hyperplasia (BPH), prostate cancer, acne, androgenetic alopecia in men, and hirsutism in women appear related to the DHT production. Two isozymes of 5 alpha-reductase have been cloned, expressed and characterized (5 alpha R-1 and 5 alpha R-2). They share a poor homology, have different chromosomal localization, enzyme kinetic parameters, and tissue expression patterns. Since 5 alpha R-1 and 5 alpha R-2 are differently distributed in the androgen target organs, a different involvement of the two isozymes in the pathogenesis of prostate and skin disorders can be hypothesized. High interest has been paid to the synthesis of inhibitors of 5 alpha-reductase for the treatment of DHT related pathologies, and the selective inhibition of any single isozyme represents a great challenge for medical and pharmaceutical research in order to have more specific drugs.
    Last edited by oswaldosalcedo; 07-23-2006 at 11:36 AM.

  12. #12
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    Quote Originally Posted by oswaldosalcedo
    sure!

    10-14-2005.
    http://forums.steroid.com/showthread.php?t=200188
    Dutasteride

    there is two 5 ar isoenzymes,dutasteride block both ,
    finasteride just block type 2 (scalp tissue).
    acne is type 1 .

    5 alpha-Reductase Isoenzyme Inhibition
    Both dutasteide and finasteride are 4-azasteroid inhibitors of 5 a -reductase , the enzyme responsible for converting testosterone to dihydrotestosterone (DHT) in the prostate. DHT is the primary androgen int the prostate and has a major role in the development and progression of benign prostatic hyperplasia (BPH) and other prostate diseases (1,2,3,4) as well as androgenetic alopecia (5,6).

    Two isoenzymes of 5 a -reductase exist (type 1 and type 2). Type 2 is the dominant isoenzyme in genital tissues including the prostate, but is also present in the skin and liver. Type "1" 5 a -reductase is also found in the skin, liver and prostate, and is the dominant form in sebaceous glands. (1,2,4).
    Finasteride is a competitive inhibitor of 5 a -reductase that selectively inhibits the type 2 isoenzyme, with which it forms a stable enzyme complex. this selective activity is attributed to a much lower affinity for the type 1 isoenzyme, and thus a slow rate of type 1 isoenzyme inhibition. In contrast, dutasteride is a competitive inhibitor of both forms of the enzyme, with 45-fold greater potency than finasteride against type 1 and type 2 isoenzymes at clinically used doses. this dual inhibition may potentially be beneficial in prostatic diseased that depend on androgens, since both isoenzymes are up-regulated in BPH while only the type 1 isoenzyme is up-regulated in prostate cancer, as noted above (2,1).



    Pharmacogenetic analysis of human steroid 5 alpha reductase type II: comparison of finasteride and dutasteride.
    Makridakis N, Reichardt JK.
    J Mol Endocrinol. 2005 Jun;34(3):617-23.

    An update on the use of 5 alpha-reductase inhibitors.
    Foley CL, Bott SR, Shergill IS, Kirby RS.
    Drugs Today (Barc). 2004 Mar;40(3):213-23. Review.

    Steroid Biochem Mol Biol. 2004 Jan;88(1):1-16.


    Selective non-steroidal inhibitors of 5 alpha-reductase type 1.

    Occhiato EG, Guarna A, Danza G, Serio M.

    Dipartimento di Chimica Organica Ugo Schiff, Polo Scientifico Universita di Firenze, Via Della Lastruccia 13, I-50019 Sesto Fiorentino, Florence, Italy.

    The enzyme 5 alpha-reductase (5 alpha R) catalyses the reduction of testosterone (T) into the more potent androgen dihydrotestosterone (DHT). The abnormal production of DHT is associated to pathologies of the main target organs of this hormone: the prostate and the skin. Benign prostatic hyperplasia (BPH), prostate cancer, acne, androgenetic alopecia in men, and hirsutism in women appear related to the DHT production. Two isozymes of 5 alpha-reductase have been cloned, expressed and characterized (5 alpha R-1 and 5 alpha R-2). They share a poor homology, have different chromosomal localization, enzyme kinetic parameters, and tissue expression patterns. Since 5 alpha R-1 and 5 alpha R-2 are differently distributed in the androgen target organs, a different involvement of the two isozymes in the pathogenesis of prostate and skin disorders can be hypothesized. High interest has been paid to the synthesis of inhibitors of 5 alpha-reductase for the treatment of DHT related pathologies, and the selective inhibition of any single isozyme represents a great challenge for medical and pharmaceutical research in order to have more specific drugs.
    good read. thanks for info bro

  13. #13
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    Quote Originally Posted by CaptainDominate
    I started using Dutasteride about 7 months ago at .5mg every day, and im not that prone to hairloss...maybe a 3 out of 10 (10 being the worst), and within 2 wks my small signs of shedding halted completely, im on the stuff year round from now on, till im done cycling...it really works, and helps keeping the prostate down too while using test products....
    Quick question though bro. did you mean .5mg or 5mg? and do you still use propecia with it? I understand that it is way better at blocking DHT than propecia, and not nescesarry to run both, but just wondering cause I still know a few bros that run both...thanks for input bro.

    And by the way, did you expreince hairloss, and then start the hairloss products? (propeica, duta...) Cause I fear I will never be able to use test again, simply because I am ridicuolosly prone to hairloss from it...the doc perscribed me a corticosteroid for inflamation the tonsils. It is called Medrol, and I was only 6 days on it, and still shedding 2 months after. It is a derivateive of test and progest..I started hairloss prodcuts after 4 cycles of test, when I started to shed. Hopeing maybe with duta, after a year, I may be able to hit test and not sure if I am on the duta yearround....

  14. #14
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    I've been running dutast for about 2 years now after running finast for about 4 years it ( dutast ) definately works a treat - i've ran test up to 750mg EW and had no probs. Test + dutast is definately the most hair friendly combo for me. I also think my hair is thicker now compared to using finast.

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    Quote Originally Posted by Duke of Earl
    I've been running dutast for about 2 years now after running finast for about 4 years it ( dutast ) definately works a treat - i've ran test up to 750mg EW and had no probs. Test + dutast is definately the most hair friendly combo for me. I also think my hair is thicker now compared to using finast.
    awesome. What about anavar and durasteride, even better in terms of hairloss?

  16. #16
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    awesome. What about anavar and durasteride, even better in terms of hairloss?
    actually var alone ( with dutast ) is the only thing that made me shed, but only mildly - my fave hair friendly cycle is prop (eg 75mg ED), tbol & var (eg 40mg of each ED) with dutast (0.5mg ED) - haven't had any probs with that combo. I think Eq is pretty safe too ( albeit weak ) although I've never run it.


    also Var is already 5 alpha-reduced ( ie. structurally related to DHT ) so in theory dutasteride would have no effect on var induced hairloss ( similarly it would have no effect on hairloss caused by primo, masteron, winny, proviron etc )
    Last edited by Duke of Earl; 07-27-2006 at 03:54 PM.

  17. #17
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    Quote Originally Posted by CaptainDominate
    I started using Dutasteride about 7 months ago at .5mg every day, and im not that prone to hairloss...maybe a 3 out of 10 (10 being the worst), and within 2 wks my small signs of shedding halted completely, im on the stuff year round from now on, till im done cycling...it really works, and helps keeping the prostate down too while using test products....
    CaptainDominate is right i am using my self for 3 weeks now and i can see little results i was diagnosted with mild benign prostatic hyperplasia (BPH) and i see results, and my tine hair is acuelly getting thicker, so if you guys using any gear that converts to DHT, use it because in future you will have prostate problem and let me tell you its not easy to deal it, and this stuff blocks most of the DHT level, if you loosing your hair because ass then it means that you have high level of DHT and soon will develope benign prostatic hyperplasia (BPH), i use it every day .5 mg/day......got Doc appointment next week and will try convince my Doctor to give me a scripe for Avodart

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    Is all hairloss caused by steroids permanent? If you aren't actually prone to MPB and are just getting it due to steroids will the hair grow back when you are off cycle?

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    Quote Originally Posted by T3/T4 GSR
    Is all hairloss caused by steroids permanent? If you aren't actually prone to MPB and are just getting it due to steroids will the hair grow back when you are off cycle?

    if you are prone to hair lost then i think you will not grow back unless you take propecia,proscar or avodart they will grow you hair back,or best is to start taking like two weeks prior your cycle and take light dosage when you off cycle,

    i personally prone to hair lost little, i took 1-ad about 2.5 years ago and my hair started thinning, i don't know if 1-Ad was cause or my age, but i started taking Dutasteride about 3 weeks ago and started see my thin hair getting thicker( i have heard that to see good results you have to take dutasteride for 6 months to see real results) i will continue using it because BPH i have, if symtoms are gone will switch to light dose maybe like propecia 1mg/day to maintain my DHT level, i hope answered your question!! try to get more information from other users out there, later bro
    Last edited by davidboy; 07-27-2006 at 06:57 PM.

  20. #20
    Do you get sexual sides from talking durasteride????

  21. #21
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    Finasteride works fine for me.

    No need to take something stronger such as Duta when Finasteride does the trick IMO.

    It's all about time............................

    Time = Results.

  22. #22
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    Quote Originally Posted by Smak
    Finasteride works fine for me.

    No need to take something stronger such as Duta when Finasteride does the trick IMO.

    It's all about time............................

    Time = Results.
    I hear you...but unfortunately for me, Propecia never really worked. Sad to say I think my hair just stopped falling out when I stopped the gear. but now this shedding sucks, just going to stay with Duta and see whats going on. Maybe in the future go back on proscar, but for now, taking a shit. I have been taking propecia for a little over a year, and still shed slightly during the year, and nasty twice during the year..

  23. #23
    Quote Originally Posted by Mike_Huck
    Do you get sexual sides from talking durasteride????
    on 500 mg test.
    difficult.

  24. #24
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    I take dura by itself w/o cycles, and no sexual sides..

  25. #25
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    I was on it for 2 weeks and couldnt get hard last nite with a hottie..

    but than i got an erection driving home while thinkin bout the nite,

    WTF>. I dunno,, i'm frustrated lol..

    DEF big time LOSS of SEX DRIVE i gotta say since i started it tho..

    Decisions.. hair or gear.. gear or hair.... or sex drive...
    I hate taking so many pillz but i guess i need viagra now too.

    the more things u take, the more side-effects.
    the more side-effects, the more pills u take.
    Last edited by Pooks; 08-14-2006 at 06:19 PM.

  26. #26
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    Quote Originally Posted by Pooks
    I was on it for 2 weeks and couldnt get hard last nite with a hottie..

    but than i got an erection driving home while thinkin bout the nite,

    WTF>. I dunno,, i'm frustrated lol..

    DEF big time LOSS of SEX DRIVE i gotta say since i started it tho..

    Decisions.. hair or gear.. gear or hair.... or sex drive...
    I hate taking so many pillz but i guess i need viagra now too.

    the more things u take, the more side-effects.
    the more side-effects, the more pills u take.
    they say side effects ususally go away after a while, just like propecia. So maybe after a few months things will get back to normal. Maybe you coudlnt pop it cause of Anxiety. Happened to me back in the day. IF your worried or frustrated at all during the course of getting an erection, I promise you that you won't get it.

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