To help answer your question....
I once ran a doc-supervised accutane treatment...accutane should be your last line of defense against acne...I hate remembering what the sides were like.
Right now, the doc has me on two different tropicals that have effectively kept any acne in check...one is a topical anti-bacterial gel called clindamycin and the other is tretinoin gel, a.k.a. Retin-A...this one-two combo is the shit and I highly recommend it to anyone that is looking for an excellent topical remedy for acne with minimal sides.
Good luck,