
Originally Posted by
fujaing
Arimidex doesn't work for me because I still look bloated with water retention even when taking 1mg a day.
I look dry and amazing while on Letrozole at 2.5mg/day. I plan to drop it to .25mg to .50mg/day after two weeks and see if the water retention comes back.
If I still look amazingly dry at 0.25mg/day of Letrozole then I'll be on it for the long term, Im talking about years. Im taking it to combat estrogen while on TRT because Im sensitive to gyno and water retention.
Im worried about the effects of long-term Letrozole usage. Particularly if it is true that one's body has a risk of developing resistance to Letrozole that after long term use the drug doesn't have any effect on one's body anymore.
I want to know if there is any data that studies longterm Letrozole usage and its effect on lipid-profiles, bone strength/density or other organs, cardiovascular health, and quality of life.