active life is active life?

[buffgator]

I never thought about it much, but an active life is an active life no matter how much I shoot, correct? Example planning for pct, if I shoot 500 or 1500mg of test it does not matter, both doses will clear me in 2 weeks, right?

[MuscleScience]

Are you confusing half life?

[buffgator]

an active life is the amount of time the substance is active in your system
half life is the amount of time the product takes for half of it to clear your system
effective period is the amount of time that the doses are high enough to be affective.
Say for instance a substance has an active life of 16 days. It would have a half life of 8 days, and the effective period is equal to the half life, only center in the middle of the active life. So after injected the substance would ramp up for 4 days. Be at a level high enough to be effective for 8 days, then clear 4 days later, for a total of 16 days.

[MuscleScience]

Is that a question or a statement? I am lost now.

[buffgator]

the question is does taking a dose at say 1500mg of test e vs 500mg extend the active life at all, or is it the same regaurdless what dose you take?

[millionairemurph]

i would think that it would be the same. Your body is what controls how fast the esters are broken down, and that should always be about the same. Thats just my thought, im no doctor. Maybe a guy like Kratos or Merc wold know better.

[taiboxa]

jagdpanther and i had a LONG as convo bout this ages ago, then this was also brough up w/ big KIG and again w/ nark.
answer is... the rate at which the molecule is cleaved and what not but i can tell u this...
the more i shoot the longer i feel like shit..
i tried this many times.. i have shot 300mg of tren one day and then felt like shit for bout 3-4 days...
another time i shot bout 1.6g of tren (enanthate ester on both of these [though i have done this experiment many many times just for shits and giggles]) and i felt like shit for bout 10 days so use that as a guide lol

[buffgator]

jagdpanther and i had a LONG as convo bout this ages ago, then this was also brough up w/ big KIG and again w/ nark.
answer is... the rate at which the molecule is cleaved and what not but i can tell u this...
the more i shoot the longer i feel like shit..
i tried this many times.. i have shot 300mg of tren one day and then felt like shit for bout 3-4 days...
another time i shot bout 1.6g of tren (enanthate ester on both of these [though i have done this experiment many many times just for shits and giggles]) and i felt like shit for bout 10 days so use that as a guide lol

thanks tai. By the way that cutting cycle you helped me with is turning out great. I just started the tren last week.

[taiboxa]

glad to hear

[peachfuzz]

actually my understanding is the active life is dependent on the dosage. i understand the active life to be how long the substance (in your case test e) promotes effects of what it was originally intended for in the body. so say you shot 500mg and just for the sake of it we will say the half life of test e is ten days. ( i know this isnt right just an example.) now in ten days the test is cut to 250mg. another 10 days and we have 125mg another ten days we have 62.5 then 31.25 then 15.625. so 40 days later there is about 15mg of test present, not really enough to exert its originally intended effects in the body.
now if you started with say 1000mg of test then it would take another ten days to be reduced to a level that no longer exerted any effects in the body.

wow i could be so wrong tho.

[sphincter]

an active life is the amount of time the substance is active in your system
half life is the amount of time the product takes for half of it to clear your system
effective period is the amount of time that the doses are high enough to be affective.
Say for instance a substance has an active life of 16 days. It would have a half life of 8 days, and the effective period is equal to the half life, only center in the middle of the active life. So after injected the substance would ramp up for 4 days. Be at a level high enough to be effective for 8 days, then clear 4 days later, for a total of 16 days.

it seems your assessment of what and how "half lives" work is incorrect. If you start with 100mg of something with a 7 day half life.. you'll have 5omg in 7 days, 25 mg in 14 days, 7mg in 21 days, 3.5mg in 28 days... etc. it halves each time. that's why they use radio carbon dating fo things since the carbon halflife is really absurdly long.

[buffgator]

an active life is the amount of time the substance is active in your system
half life is the amount of time the product takes for half of it to clear your system
effective period is the amount of time that the doses are high enough to be affective.
Say for instance a substance has an active life of 16 days. It would have a half life of 8 days, and the effective period is equal to the half life, only center in the middle of the active life. So after injected the substance would ramp up for 4 days. Be at a level high enough to be effective for 8 days, then clear 4 days later, for a total of 16 days.

isnt that what I said?

[magic32]

In short, they are quite separate with the Active Life being the time a drug spends at the active site (that place, often a receptor site, where it impacts the body). Half Life is the amount of time it takes for 1/2 of a drug to evacuate the body. Many people mistakenly assume that in this same amount time (let's say 2 days), the other half will be cleared. This is not true as only half of the remaining second half (or 1/4) will clear by day 4, followed by half of that or 1/8 by day 6, and so on. Thus a drug's life cycle experiences multiple half-lives until it reaches the last one known as the terminal half-life.

For a better understanding of this, and of the factors involved see my signature.
It would be nice to know that someone clicks on them occasionally.

[buffgator]

thanks magic. If i follow you you are saying that a half life can be one of two things.
1. 50% of the product has been excreted through metabolism and other factors where it has actualy left the body
2. 50% of the product is inactive, does not mean it has left the body, but prehaps has been shuttled elsewhere to places where it will have no desired affect.

[magic32]

thanks magic. If i follow you you are saying that a half life can be one of two things.
1. 50% of the product has been excreted through metabolism and other factors where it has actualy left the body
2. 50% of the product is inactive, does not mean it has left the body, but prehaps has been shuttled elsewhere to places where it will have no desired affect.

This is incorrect!
Anytime a drug is in your system it is working. However, the degree of its impact is often based on the amount present. This is why the focus is typically on building up and stabilizing levels. Thus, the remaining 50% is still working (still active) but at a significantly reduced degree.

This is why long esters came into being...to be shot once a month.
For example, let's say you shoot 250mgs of Enth on the first of the month. With an 8-day (GENERIC, IT'S REALLY 9 - 10) half life you're down 50% of hard working Testosterone but this is a scant half of what the bb’er needs operating, though it’s fine for the HRT’er. By day-16, or the 2nd half life there's 25% (half the 50) left and again still working, by day-24 (3rd half life) it's down to 12.5% and by the first (4th half life) down to a mere 6.25%, but you're ready for another injection.

Whether you feel it working is subjectively immaterial, as long as there are no contraindications (conflicting medications; thyroid, pituitary or other glandular issues) then the drug has no choice but to impact the body.

That’s why we're incredulous of the so-called ‘Non-responders’ to Testosterone. Granted on occasion one of the above issues is negating Test effectiveness, or AI’s and Serms are to blame, or the gear is just bad, but more often it’s a CHECKLIST problem and one or more of the following are not in place:


STEROID CHECKLIST

• Appropriate steroid administration includes using the proper goal-oriented compound(s), dosage(s), timing & duration.
• Appropriate muscle fiber breakdown includes lifting heavy, effectively, and regularly.
• Proper amount of rest and recuperation time.
• Appropriately increased protein consumption.
• Appropriately increased overall calories.
• Proper restriction of empty, junk food calories.

[buffgator]

an active life is the amount of time the substance is active in your system
half life is the amount of time the product takes for half of it to clear your system
effective period is the amount of time that the doses are high enough to be affective.
Say for instance a substance has an active life of 16 days. It would have a half life of 8 days, and the effective period is equal to the half life, only center in the middle of the active life. So after injected the substance would ramp up for 4 days. Be at a level high enough to be effective for 8 days, then clear 4 days laterbut it really countinues to diminish at one half of the substance left. days.

so black is wrong, and should be replaced with whats in red?

[magic32]

WELL...

an active life is the amount of time the substance is active in your system
half life is the amount of time the product takes for half of it to clear your system effective period is the amount of time that the doses are high enough to be effective.
Say for instance a substance has an active life of 16 days. It would have a half life of 8 days, and the effective period is equal to the half life, only center in the middle of the active life.
IF IT HAS AN ACTIVE LIFE OF 16 DAYS IT WILL HAVE EXPERIENCED SEVERAL HALF LIVES PRIOR TO REACHING DAY 16, THUS DAY 8 WOULD NOT BE THE FIRST HALF LIFE. LOOK AT THE EXAMPLE I GAVE FOR AN 8 DAY HALF LIFE OF ENTH…IT STILL PERSISTED PAST THE END OF THE MONTH. YOU’LL HAVE TO DO THE MATH BUT A 16 DAY TERMINAL LIFE DRUG WOULD HAVE ABOUT A 2 DAY HALF LIFE.

So after injected the substance would ramp up for 4 days.
THIS IS INCORRECT. ONE ADMINISTRATION DOESN’T RAMP OR ACCUMULATE, IT JUST EXISTS AND DEGRADES. IT IS THE PROPER TIMING AND AMOUNT OF SUBSEQUENT DOSES THAT CAUSE PDC (PLASMA DRUG CONCENTRATIONS) TO APPROACH THE MEAN STEADY STATE WHERE IT LEVELS OFF.