Letrozole Information/effects

[IMBIGRU]

Does Letro effect the brain cause im feeling clear different on it.... My sex drive is way down.. I got tears in my eyes watching Vision Quest! lol... kinda felt like i was on clomid. Im taking 2.5 a day just to jump start it then im backing off to .5 Everyday Im running a pretty big cycle.....
I like the feel of no bloat and the loss of water but my muscles fell kinda cramped at times , my strength seem pretty normal but Im afraid to go over heavy cause i feel kinda (dry) ( I have read about all this but why does it happen??) and also

Can Letrozole be use for post cycle ?

what would the effects of Letrozole be on sperm count?
How would u all take the Letrozole??? could I go EOD

[wingding]

I use letro to get rid of the blues and gyno and it works very well. I only run .25 as needed. I used to run it everyday but it made my joints, especially my knees ache. Its my understanding that it will drop your estrogen to zero if you're not careful. You need to have some estrogen.

[kfrost06]

The reason why you feel dry is because at 2.5mg ED you are eliminating all your estrogen. Estrogen is very important in maintianing your salt levels which in turn retain water weight, so your electrolyte levels and water weight are way down which is giving you that dry feeling and can cause injury and cramps and loss of muscle and bone strength. You are experience a loss in libido and most likely erection problems again because you have no estrogen and estrogen is required for proper sexual function in males. In addition you are lowering your immunity, increasing your LDL and decreasing your HDL as well as many other problems. There is no need to take it at those levels unless you are doing a gyno reversal and then for only 2weeks. I suggest you start tappering down now, Decrease by 0,25mg ED till you get to 0,50 - 0,25mg ED.

GL

[mx3]

0.25 eod works for me. and yes you can use it in pct.

[IMBIGRU]

I have only been taking it for 2 weeks.... why do i need to taper? It funny that you mentioned my immunity system.... cause i been have a sever caught ( worse that test/fina caugh/..... why do i need to taper? I thought I would just skip my next dose and then run .25 ed

[IMBIGRU]

how does letro get rid of the blues?? anyway

[IMBIGRU]

have any idea?

[HORSE~]

These should help

Read this
http://forums.steroid.com/showthread.php?t=319202

And this
http://forums.steroid.com/showthread.php?t=199826

[Chuck_R]

0.25 eod works for me. and yes you can use it in pct.

Agree..0.25 eod has been helping me with minimal side effects after the first week or so.

[IMBIGRU]

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SWEET!!! thanks
Letrozole

(Femara)

Letrozole is the chemical name of Novartis’ selective third generationAromatase Inhibitor (AI). This drug was developed to fight breast cancer by inhibiting the aromatization. It is usually used as a part of an aggressive treatment in post-menopausal women, to fight and reverse the spread of breast cancer after other treatments (such as Tamoxifen therapy) has failed. It’s probably the most efficient product on the market for this purpose currently (5) It is very similar in structure and action to it’s predecessor Arimidex.

Letrozole also does quite a few things which would be of interest to both bodybuilders and athletes. Firstly, it has been shown to reduce estrogen levels by 98% or greater(1). In at least one documented incidence, Letrozole reduced estrogen in the test subject to undetectable levels, and increased LH, FSH and SHBG (4). Clearly this is all of interest to bodybuilders, as less estrogen in the body means less chance of certain side effects such as water-retention, Gynocomastia, and acne. This makes Letrozole an appropriate choice for even the heaviest bulking or cutting cycles including harsh androgens. Also, if you are a competitive bodybuilder, Letrozole is a must have product for contest prep; no other Ancillary compound will produce a dry and tight look like Letro will.


An effective dose of Letrozole is .25-.5mg/day (I use .25mgs/day), but be forewarned, if you go over that amount, it can kill your sex drive. Also worth noting is that there's a rebound effect on your estrogen when you come off Letrozol. Maximum inhibition of the aromatase enzyme has been found to happen at doses as low as 100mcg! (2)

Letrozole's effects on serum lipids (cholesterol, both HDL and LDL) are, in the words of one researcher: "inconsistent. " Clearly, however, you’ll eventually suffer an impaired lipid profile and immune system if you keep your estrogen levels too low for too long. Your sex drive will also probably suffer from extraordinarily low levels of estrogen present.

As previously mentioned, Letrozole can be used to raise LH and FSH (which are hormones which signal your testes to produce more testosterone). It also, of course, will raise your testosterone levels (6) via this mechanism. Again, this is of interest to athletes and bodybuilders for obvious reasons. Letrozole, of course, can be used for post-cycle-therapy (PCT) to raise test levels, but for various reasons, Tamoxifen may be a better choice. Still, I have successfully used Letrozole for this purpose.

How good is this compared with Aromasin and Arimidex, it’s too other main rivals? Well, In non-cellular systems, letrozole is 2-5 times more potent than anastrozole and exemestane in its inhibition of the aromatase enzyme and activity, and in cellular systems it is 10-20x more potent! It also lasts quite a long time in your body,but takes awhile to get going… Letrozole has a whopping 2-4 day (!) ½ life, and you need to take Letrozole for 60 days to get a steady blood plasma level (8).

Those are impressive numbers, but here’s one of the most interesting things about Letrozole:

It may reduce/eliminate/reverse existing gynocomastia!

In a study conducted on mice (*no, I know it’s not perfect), gyno-like-changes in the mammary gland were totally destroyed ! Here’s a direct quote from that study:

“Our results also indicate aromatase overexpression-induced changes in mammary glands can be abrogated [destroyed] with very low concentrations of the aromatase inhibitor, letrozole.”(7)

In addition, I’ve used Letro to get rid of my own gyno, as has a friend of mine, and we both used it at a dose of 2.5mgs/day, tapering down to .25mgs/day, and then finally off….the gyno never returned in both our cases.

I’d say that this stuff is pretty great, considering its availability and cost (when you consider the fact that .25mgs/day is more than enough protection from estrogen-related sides on most cycles), not to mention it’s overall utility for a variety of functions (destroying gyno, preventing estrogenic sides, and for PCT).

[kfrost06]

I have only been taking it for 2 weeks.... why do i need to taper?

When you stop abruptly you will experience a rebound effect in estrogen production and it will happen fast. Coming off slowly is very important. Many people including myself like to switch to a SERM when finishing a letro gyno reversal that way when your body starts producing estrogen again you can prevent (limit) it's binding to the ERs in the breast, i.e. to prevent gyno.


GL

[IMBIGRU]

like switch to nolvadex ? Im going to cut back to like .25 ed
how does this stuff effect the brain?? I feel like im on clomide or something... I feel really happy and sleep great... usually when im in mid cycle... I dont sleep well and I worry about stupid stuff... and when I eat I get so full/bloated after I eat I have to sit down a while... but i dont feel any of that stuff now............... Im not bloated at all... but my sex drive is down and I got sick..... I ran 2.5 a day for 2 weeks... I was just going to run it till I noticed it was working and ....WOW all at once also I look huge right now cause I been able to eat more and I'm not holding as much water......... the rebound effect worries me!!