IGF and Neurological Benefits

[Lavinco]

Can anyone elaborate on any neurological benefits that they know of (preferably first hand) with IGF-1?

Let me start out by letting you know where I am going with all this. I recently read that IGF-1 has proven to greatly reduce the symptoms of Rett Syndrome in mice models.

Rett Syndrome is a debilitating disorder that affects mostly girls and robs them of their every ability by their mid 20s and eventually takes their lives.

It is caused by a mutation of the mecp2 gene in the X chromosome. Girls have 2 X chromosomes throughout the body's cells while boys have only 1. Boys that get the disorder usually die in the womb from rapid regression while girls live to be 20-40, depending on the severity and type they have.

I am not new to this forum and know a little about a lot of things, but not much about IGF-1 other than some past reads on here years ago.

So I am wondering what everyone knows in relation to mental side effects from their own observation?

Thanks in advance.

[ScotchGuard]

The only thing I've read about neurological use of IGF was with athletes. This study found that athletes were using IGF on sport specific muscles to improve coordination and performance. I don't think it will reverse a genetic mutation of a gene. Man, that's scary.

[Lavinco]

The only thing I've read about neurological use of IGF was with athletes. This study found that athletes were using IGF on sport specific muscles to improve coordination and performance. I don't think it will reverse a genetic mutation of a gene. Man, that's scary.

It doesn't actually reverse a genetic mutation of certain genes, but rather activates them from their dormant and undeveloped stages. "Mutatation" is perhaps not as accurate as science would have it. I personally think that with Rett, the mecp2 gene is simply underdeveloped.

Someone said on here a while back, that IGF is known to activate dormant genes which is bad if you have a cancer gene but good if you have Rett Syndrome.

The cure exists in mice. They just have to fine tune it for girls with Rett's. I figure that this place is great for my research because the body building community is much farther ahead than the research community because BB'ers experiment with this stuff all the time.

Any other thought from anyone?

[ScotchGuard]

Malignant tumors produce an IGF like substance that causes their rapid growth. The conclusion that's drawn in most cases is that synthetic IGF will also increase the growth of the tumor. I haven't read a definitive study that showed that IGF on the external membrane of the tumor will increase their growth rate. I've also heard people talking about HGH causing the increased growth of tumors. I'm not sure if that conclusion is also accurate. I have read studies that allude to that conclusion but I'm not sure if 1,000 times the normal dosage into mice is an accurate parallel to how human's are taking HGH.