
Originally Posted by
Swifto
You can take Tamoxifen and Tren/Deca. The ones that say this are meerly repeating others views without understanding why not themselves.
The true problem is estrogen or the estrogen receptor (ER). Progesterone is synthesised in reponse to estrogen in breast tissue. So SERMs such as Tamoxifen than downregulate the ER in breast tissue also downregulate the PgR (Progesterone Receptor).
Prolactin is regulated and secreted by estrogen aromotasing and secreted at the ant. pituitary lobe (the same as thyroid hormones). Compounds than interect with the ER can cause prolactin (PRL) to rise.
Using an AI should, in theory, prevent PRL from rising, but this doesnt always happen. So its advised to keep a dopamine agonist (caber, prami) on hand incase of PRL increasing.
So,
Use an AI (Aromasin) and keep both Tamox and Caber on hand IMHO. If you run into problems, run Tamoxifen at 20-40mg/ED, and you could if PRL is elevated run Caber/Prami.