High Total Test and Low Estrogen ???

[fm2002]

Was having lunch with a friend I had not seen in some time and who I had helped in starting a basic HRT program. He had gone reservation a bit and was doing 250mg of Test E every 8 days. AI (Arimidex) .25mg every 3 days. I had told him to do about half of the Test or 125mg. Because of this revelation I said he better take a blood test.

His total T was 10.53 ng/ml

Estrogen 16.0 pg/ml

The Total T result makes sense at the amount he's doing, but the E2 level IMO seems really low. He didn't get his Free T checked.

(To contrast I'm doing 150mg Test E every 10 days and .5mg Arimitex every other day and my Total T is 9.8 and my E2 is 18.)

Wondering why his E2 is so low with so much Total Test ???

Just read this at lef:

[Low Free Testosterone, Low Estrogen, High Total Testosterone: This situation suggests excessive SHBG levels, making sufficient testosterone unavailable to target tissues. The elevation of SHBG explains why some older men who are on testosterone repla***ent therapy do not report a long-term beneficial effect, that is, the administered testosterone becomes bound by SHBG and is not bioavailable to cellular receptor sites where it would normally produce an effect. Suggestions include:

Inhibit aromatase by following some of the recommendations in the previous section, since low testosterone and high estrogen are involved in excess SHBG activity.]

Have already instructed my friend to test for Free T and SHBG.

Any other ideas???

[kelkel]

Test for Albumin also. Is the E2 a sensitive assay? In my opinion your both doing to much adex. You should be able to get by on far less. Maybe .25 x2 or at the most x 3 per week based on BW. Many of us here have crashed our E2 and it's not fun. It's a needed component for your health and well being. Low E can be just as bad as high E.


We have been talking about the above recently. Read these threads:

http://forums.steroid.com/showthread...-SHBG-from-LEF

http://forums.steroid.com/showthread...TRT-components

[fm2002]

Test for Albumin also. Is the E2 a sensitive assay? In my opinion your both doing to much adex. You should be able to get by on far less. Maybe .25 x2 or at the most x 3 per week based on BW. Many of us here have crashed our E2 and it's not fun. It's a needed component for your health and well being. Low E can be just as bad as high E.


We have been talking about the above recently. Read these threads:

http://forums.steroid.com/showthread...-SHBG-from-LEF

http://forums.steroid.com/showthread...TRT-components

Will definitely have a read. In my case I test my blood all the time and my E2 on .5mg EOD kept me in the high 20's where I wanted to be. It was when I switched my brand of Arimidex that my E2 went way down to 18. Either old stuff was weak or new stuff strong? I've knocked my intake down to every 4th day .5mg and will test my blood after 4 weeks on this regime.

[kelkel]

Sounds like a plan. Post up how your levels turn out please.