clenbuterol?

[mattaloo]

Why should someone not be taking clenbuterol? Like high bp or low bp has thyroid problem etc. things of that nature.

[cutting_king]

Well clenbuterol is a central nervous system stimulant so it increases your heart rate and blood pressure, so I wouldn't touch it if you have any heart or blood pressure issues.

[mattaloo]

So is there no reason why someone shouldn't take it for weight loss?

[cutting_king]

So is there no reason why someone shouldn't take it for weight loss?

It might be worth looking up the contraindications from one of the manufacturers for a comprehensive list of other meds to avoid taking with it, they should also include any conditions that would be made worse by taking it too

[Duc d'Volpe]

The side effects you can get from clenbuterol are excruciating, and is not worth the minimal results you get from it. I am never touching this stuff, ever.

[cutting_king]

The side effects you can get from clenbuterol are excruciating, and is not worth the minimal results you get from it. I am never touching this stuff, ever.

I'm not a fan of the shaky hands but apart from that I don't get bad sides from clen. It's probably quite an individual thing and related to dose.

As long as you ramp up slowly, most of the sides can be kept at bay

[mattaloo]

Thx I'll check it out

[Atomini]

Clenbuterol is horrible. I used it very avidly years ago, but after a certain point I decided to never touch the stuff EVER AGAIN.

When it gets to the point where you can literally FEEL the beats of your heart vibrating through the bed when you are laying down... its time to call it quits for good.

I don't care if people ramp up the dose or any of that junk, you are risking serious cardiovascular and pulmonary damage when you use it, even if you don't 'feel' anything bad when you use it. What might be going on inside you is a whole different ballgame.

[cutting_king]

Clenbuterol is horrible. I used it very avidly years ago, but after a certain point I decided to never touch the stuff EVER AGAIN.

When it gets to the point where you can literally FEEL the beats of your heart vibrating through the bed when you are laying down... its time to call it quits for good.

I don't care if people ramp up the dose or any of that junk, you are risking serious cardiovascular and pulmonary damage when you use it, even if you don't 'feel' anything bad when you use it. What might be going on inside you is a whole different ballgame.

Agreed. I believe i read that it increases the size of your heart if you use it extensively which is a pretty scary thought

[Atomini]

Yes, that is true and it is perhaps the only thing I am worried I have done to myself. Forever as I get older, my past use of clen will always be in the back of my mind and I wonder if any heart issues might arise in 15 years or more and could be traced back to clen.... Knock on wood.

[Atomini]

There are far better compounds and methods for stripping fat off the body than something that has a high potential of blowing your heart through your ribcage years down the road.

[Lord Me of There]

There are far better compounds and methods for stripping fat off the body than something that has a high potential of blowing your heart through your ribcage years down the road.

Such as? I was thinking of clen to help me shed off the last few pounds that are driving me nuts, but I've been spooked for the same reasons you brought up, by the side effects and down the road issues.

[Duc d'Volpe]

Such as? I was thinking of clen to help me shed off the last few pounds that are driving me nuts, but I've been spooked for the same reasons you brought up, by the side effects and down the road issues.

If you have a legit source for DNP (and that's very big if, I have only one guy that I would trust), I would use that. Contrary to popular belief, DNP is actually very safe, if you got a legit source for it.

[Atomini]

To be honest I wouldn't touch DNP, just because it is a poison to the body and not a drug. Can it be used safely? Yes. But it is something completely foreign to the human body, and the pathways by which it does what it does is the nature of a poison - very very similar to how things like cyanide works. There is a reason why it is used as a pesticide and an explosive additive in TNT and other explosives. Diet and cardio are always first and foremost to fat loss, of course. T3 is a good choice with a low dose of gear to stave off muscle catabolism. And then you have promising compounds such as GW-501516, which I am currently running for the first time (see my log).

[Duc d'Volpe]

To be honest I wouldn't touch DNP, just because it is a poison and not a drug. Diet and cardio are always first and foremost to fat loss, of course. T3 is a good choice with a low dose of gear to stave off muscle catabolism. And then you have promising compounds such as GW-501516, which I am currently running for the first time (see my log).

DNP has been shown in studies to actually have cancer, cardiovascular and neurological protective effects. A low dosage of 250mg ED and at least a gallon of water consumed everyday for 2-3 weeks is actually pretty safe and will provide very satisfactory results.

It's not unusual to see people lose up to 20 lbs or more pure fat in those 2-3 weeks.

[Lord Me of There]

To be honest I wouldn't touch DNP, just because it is a poison to the body and not a drug. Can it be used safely? Yes. But it is something completely foreign to the human body, and the pathways by which it does what it does is the nature of a poison - very very similar to how things like cyanide works. There is a reason why it is used as a pesticide and an explosive additive in TNT and other explosives. Diet and cardio are always first and foremost to fat loss, of course. T3 is a good choice with a low dose of gear to stave off muscle catabolism. And then you have promising compounds such as GW-501516, which I am currently running for the first time (see my log).

Thanks for the info and I will immediately go and check your log as your thinking seems to line up with mine. In a previous lifetime I worked extensively with exlosives and am quite familiar with the accelerant properties of DNP...unbelievable that someone would think to voluntarily ingest that stuff...allthough it may be one hell of a vascular dialator.

[Atomini]

DNP has been shown in studies to actually have cancer, cardiovascular and neurological protective effects. A low dosage of 250mg ED and at least a gallon of water consumed everyday for 2-3 weeks is actually pretty safe and will provide very satisfactory results.

It's not unusual to see people lose up to 20 lbs or more pure fat in those 2-3 weeks.

I did not know this. I will have to check these studies out.

Thanks for the info and I will immediately go and check your log as your thinking seems to line up with mine. In a previous lifetime I worked extensively with exlosives and am quite familiar with the accelerant properties of DNP...unbelievable that someone would think to voluntarily ingest that stuff...allthough it may be one hell of a vascular dialator.

It was actually discovered when people who worked in munitions factories during WW1 were losing vast amounts of fat. When it was discovered that DNP was the cause, it became a perscription drug for a time during the 1920s and 1930s to treat obesity and weight gain. Unfortunately it was causing issues in people such as hyperthermia, and cataract formation in the eyes (due to all of the excess oxidization occurring from all of the metabolic accellerant properties). They then pulled it from the market and halted its use completely in the field of medicine. I know that DNP can be used safely with lots of water and antioxidants to combat the high amount of oxidation and free radical formation, but it's just something i'm not so sure i'd like to try. This is why I have been dabbling in HGH and now GW-501516 for fat loss.

[Duc d'Volpe]

^Here is a few

Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: the gentle face of Janus.
http://onlinelibrary.wiley.com/doi/1...02198/abstract
This landmark paper obviously made an effort to change the widespread misperception that DNP is only dangerous and toxic It points to protective effects in the brain, possible treatments for neurodegenerative diseases like Parkinson's, and even extension of lifespan.

The mitochondrial uncoupler 2,4-dinitrophenol attenuates tissue damage and improves mitochondrial homeostasis following transient focal cerebral ischemia.
http://onlinelibrary.wiley.com/doi/1...5.03328.x/full
This is one of many studies showing that DNP is protective in models where blood flow is interrupted (stroke, heart attack) and then restored. Usually there is a massive release of oxidative stress when this happens. DNP greatly limits this.

Regulation of human male germ cell death by modulators of ATP production.
http://ajpendo.physiology.org/content/290/6/E1145.short
This study shows that DNP prevents germ cell apoptosis (death). This is the same thing testosterone does. When apoptosis is accelerated, you get all kinds of fertility problems. Looks like DNP may actually help here, depending on the mechanism behind the irregular apoptosis.

Energy requirement for degradation of tumor-associated protein p53.
http://mcb.asm.org/content/4/3/442.abstract
p53 is a transcription factor recognized as having anti-cancer effects in cells. There's only good news here with regards to DNP, as DNP has been shown to increase p53 expression. This has been shown both directly in this study and also via AMPK, which DNP clearly activates. AMPK is likely the mechanism through which DNP exerts this anti-cancer effect.

The mitochondrial uncoupling agent 2,4-dinitrophenol improves mitochondrial function, attenuates oxidative damage, and increases white matter sparing in the contused spinal cord.
http://online.liebertpub.com/doi/abs...u.2004.21.1396
This paper showed that pretreatment with DNP significantly reduced the damage from a bruising injury to the spinal cord. Again, this has to do with a reduction in oxidative stress.

[Duc d'Volpe]

Also the cause of cataract is because it can actually "melt" the myelin sheet, but only in women and in high dosages. Male myelin sheets are much more durable and can handle it.

[Atomini]

Myelin Sheaths*

Just felt the need to correct that lol. I will check out those links for sure, thanks.

[Duc d'Volpe]

Oh yeah, sheath*, I derped out a little lol.

[Bonaparte]

I'd say that the main contraindications to Clen would be hypertension and cardiovascular disease (which are also the side effects).

[syd-bloke]

Dont listen to these guys, here is a better dose for clen, grab the whole bottle or container, make sure its all you got, then walk to the toilet, then flush it all. You will see the results immediately!