
Originally Posted by
Quester
Also, the androgens make you a little more on edge so you have greater sympathetic nervous system activation which among many other things, constricts blood vessels a little and increases the heart's contractile force and rate.
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Additionally, testosterone and synthetic testosterone increase hematocrit, the blood's O2 carrying capacity, which thickens the blood, which requires greater contractile force to move resulting in higher BP. Among other things, higher BP compromises the blood vessels walls, at the tissue level, that's why it is to be avoided.