I have been on T therapy since the begining of the summer. I checked into it because i was constantly depressed and tired and couldn't get motivated. My labs were 250 test and my estrogen was just in the high range. I started with 1 ml every 2 weeks and then slowly worked up to 2 as a matter of fact I just got my first inject with 2 yesterday. I've been having problems with the ups and downs so i asked my doctor if i could inject every week and he said that it didn't work that way. So we just kept increasing the dose. My last blood test when i was taking 1.5ml showed that my levels shot up to about 800 three days after the injection and dropped to below 600. Pretty much within hours after i get my injection my mood starts to change and i can feel the depression lifting. Towards the end of the two weeks my wife tells me its about time for the shot. The kids start to drive me crazy and i can't stand noisy places etc. I have developed another issue now. I am having problems keeping an erection during sex. I am constatnly horny since starting the therapy but i can't keep it up. I have never had this problem before. My syptoms never included problems with getting it or keeping it up. Would this be caused by the swings in my T levels from the begining of the two weeks to t he end, or maybe because my estrogen level is sky high. please help....