Once per week with both sust and eq... I have never had anyone tell me ed or eod for either sust or eq. that sounds crazy man. They both have long lasting esters.... Some even stretch it to 10 days.. majority rules on this one bro.. Maybe you didn't understand what I am taking. Sust 250 @ 325/wk and eq 200 at 300/wk...may bump the level a bit but not much..