i am very interested in the long-term effects. The studies you cite seem to indicate a low level of toxicity for the kidneys, liver, and cardio-vascular system... indicating there is no increase in pulse levels which is unique among metabolic accelerators. I am worried about this information because it was studied in 1939 (referring to Bell, Jacques. 1939. Etude biologique des produits dinitres chez l'homme. Medecine. 19:749-54.)... do you think this still holds true and are there more current studies on this? I understand that back then it was actually administered as a fat loss agent, which would prompt more clinical studies of DNP for this purpose, but are there more current ones that might analyze more the effects of DNP on cancer and the cardio-vascular system?