this is a good post to read for people interested in DNP, but i question some of the info in here. anyone want to help clear these up?
1.Effectivity: perhaps replace with efficacy? ( i know its nitpicky, but it sounds ignorant)
2. All over messgeboards I read that an ECA boosts metabolism by 3%,
Clen + T3 20% and DNP 50-75%!
I don't know where people get these numbers but it is not true!
actually every 100mg of DNP has been reported to increase metabolism by ~11% ( Harper et al. Mitochondrial uncoupling as a target for drug development for the treatment of obisity. obesity reviews. 2001) so 400mg would be about 45% increase, correct?
3. DNP IS NOT SUITABLE FOR WOMEN AND MORBIDLY OBESE PEOPLE!!
Most of the original studies were on morbidly obese people, as for women, can anyone back that up with fact?
4. DNP is so dangerous, because it doesn't involve in a feedback system
most drugs lack a feedback system, this does not make them dangerous. the danger for DNP lies in the fact that the ED50 to LD 50 is very small, so the difference between being effective and being deadly is small.
5. T3 is NOT catabolic!
t3 without a doubt leads to a negative nitrogen balance (loss of LBM). if this is in question check out the paper i referenced for 2.
6. ethanol (Nail polish remover)
nitpicky again, they do use it in nail polish remover, but it sounds unreasonable. the ethanol is everclear or something similar that people drink all the time, nail polish remover makes it sound like they are feeding people industrial chemicals.
7. So a 20 day cycle @ 200 mg ED, will result in a 540 mg peaklevel which is a very comfortable dose for any healthy grown man!
what i get at steady state is ~260mg using a 200mg dose everyday, using this equation: Css = (dose * t1/2 * Bioavailability)/
(interval * (0.693) * VD), but ive assumed bioavailability and interval to be 1, so correct me if im wrong.
anyway, im not trying to be obnoxious, but i think some of this info is questionable, and some is worded a bit strange.
Reply With Quote