Anybody seen the latest studies? This is stuff I just read, so it's all new to me too. I'm just looking for the truth. seems this old info isn't correct anymore, by new study. You'll have to search around but as I recall it goes like this:
1. don't do 2 on 2 off with clen, etc. go straight through for long cycles. On every 3rd week (so, week 3, week 6, week 9 etc.) take benadryl every night (check dosage amount, I can't remember) before bed. This takes care of the receptor downregulation (a la ketotifen).
2. DON'T use E/C, because they say now that it DOES cause downregulation. This seems to be a controversy, though.

Anyone who finds more on this please post. I for one would really like to get the correct info, as I plan on cutting with clen in 2 weeks.