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  1. #1
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    Bro we're not talking about the samething, I'm talking about LR3 IGF-1, not the results of HGH use on IGF-1 levels.

    IGF-1 is not LR3 IGF-1, I know people call it IGF-1. That's where the confusion comes in, you are trying to apply a study done with HGH and it's results on IGF-1 levels. That has nothing to do with LR3 IGF-1. LR3 IGF-1 is an anolog of rhIGF-1, but they are not the same, nor is IGF-1 elevated by the use of HGH.

    JohnnyB

  2. #2
    Quote Originally Posted by JohnnyB
    Bro we're not talking about the samething, I'm talking about LR3 IGF-1, not the results of HGH use on IGF-1 levels.

    IGF-1 is not LR3 IGF-1, I know people call it IGF-1. That's where the confusion comes in, you are trying to apply a study done with HGH and it's results on IGF-1 levels. That has nothing to do with LR3 IGF-1. LR3 IGF-1 is an anolog of rhIGF-1, but they are not the same, nor is IGF-1 elevated by the use of HGH.

    JohnnyB
    god ! the moderators dont read relevant posts !

    see:
    The Journal of Clinical Endocrinology & Metabolism Vol. 88, No. 11 5221-5226
    2003, by The Endocrine Society.

    "High Dose Growth Hormone Exerts an Anabolic Effect at Rest and during Exercise in Endurance-Trained Athletes
    M. L. Healy, J. Gibney, D. L. Russell-Jones, C. Pentecost, P. Croos, P. H. Sönksen and A. M. Umpleby
    Department of Diabetes and Endocrinology, GKT School of Medicine, St. Thomas Hospital, London, United

    r-hGH-treated

    ------------------ Baseline --------- 1wk-----------4 wk--------- /Placebo-
    IGF-I (nmol/liter) 24.6 ± 3.0 / 89.6 ± 12.21-- 106.3 ± 16.41/ 25.8 ± 2.7-- 25.4 ± 2.7-- 25.2 ± 2.6
    fT3 (pmol/liter) 5.1 ± 0.3 6.0 ± 0.12 6.1 ± 0.22 4.8 ± 0.2 4.9 ± 0.2 4.8 ± 0.1
    fT4 (pmol/liter) 15.5 ± 1.5 11.5 ± 1.02 10.6 ± 0.92 15.8 ± 1.6 15.6 ± 1.7 15.8 ± 1.5
    Testosterone (nmol/liter) 18.3 ± 3.2 18.5 ± 3.4 18.5 ± 3.3 16.7 ± 2.6 16.3 ± 2.6 16.4 ± 2.2
    Glucose (mmol/liter) 4.7 ± 0.3 5.5 ± 0.5 5.3 ± 0.2 4.5 ± 0.4 4.2 ± 0.2 4.4 ± 0.3
    Insulin (mU/liter) 7.9 ± 1.6 22.6 ± 3.92 16.0 ± 9.32 6.0 ± 0.3 5.6 ± 1.9 9.3 ± 2.4
    HOMA IR 1.4 ± 0.2 5.1 ± 1.02 3.3 ± 0.62 1.1 ± 0.4 1.0 ± 0.3 1.6 ± 0.5
    Total cholesterol (mmol/liter) 4.3 ± 0.3 4.0 ± 0.5 4.1 ± 0.3 3.4 ± 0.3 3.3 ± 0.3 3.5 ± 0.6
    Triglyceride 1.1 ± 0.2 2.0 ± 0.5 1.3 ± 0.1 0.6 ± 0.1 0.7 ± 0.1 0.5 ± 0.1
    LDL cholesterol (mmol/liter) 2.6 ± 0.3 2.2 ± 0.3 2.3 ± 0.3 1.6 ± 0.4 1.6 ± 0.3 1.6 ± 0.5
    HDL cholesterol (mmol/liter) 1.2 ± 0.1 1.0 ± 0.1 1.1 ± 0.1 1.5 ± 0.1 1.5 ± 0.1 1.7 ± 0.2
    Body weight (kg) 74.4 ± 1.1 76.5 ± 1.72 77.9 ± 1.62 74.9 ± 3.4 74.9 ± 3.4 74.7 ± 3.3
    Lean body mass (kg) 57.6 ± 1.1 61.0 ± 1.22 61.6 ± 2.5 61.8 ± 2.4
    Total body fat (kg) 11.4 ± 1.4 11.6 ± 1.7 9.8 ± 1.9 10.1 ± 2.0
    Trunk fat (kg) 4.7 ± 0.7 4.5 ± 0.9 2.8 ± 0.9 2.8 ± 0.9

    There was no change in IGF-I levels in the placebo-treated group throughout the observation period. In contrast, in the r-hGH-treated group, IGF-I levels rose markedly, reaching levels outside the physiological range (P < 0.001; Table 2 ). These changes occurred within 7 d of commencing r-hGH administration and did not change further over the remaining 21-d period of r-hGH administration."

    ------------------------------------
    igf is elevated 4 fold ! from hgh.

    and now like always, johnny b dissapears..................
    Last edited by oswaldosalcedo; 10-27-2005 at 11:05 AM.

  3. #3
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    Quote Originally Posted by oswaldosalcedo
    god ! the moderators dont read relevant posts !

    ............
    Bro I could say the same about you, but say things about each other is useless and leads no where and the post needs to be relevent to the discussion, which is LR3 IGF-1. I'm talking about LR3 IGF-1 and you are talking about IGF-1 and rhIGF-1. So since we are not talking about the same thing it's useless to continue. Bro there is a difference and a big one at that, when we are looking at studies.

    The studies we do have on LR3 IGF-1 are on rats and pigs, which aren't humans, so they can only be used as references, not solid proof of what would happen in humans.

    It seems you think LR3 IGF-1 is a waste, which is fine, but by posting studies on IGF-1 and rhIGF-1, you're not proving your point, cause they don't apply. Studies done with LR3 IGF-1 in them, will say IGF-1 and it's analog(s) in them or say LR3 IGF-1. Those studies were done with IGF-1, rhIGF-1 and/or LR3 IGF-1, some may include IGF-II.

    Have you every tried LR3 IGF-1?

    You are getting frustrated, because we are not talking about the samething, but you think we are. It's not that hard, if it doesn't say IGF-1 anolog(s) or LR3 IGF-1 in the study, it doesn't apply to LR3 IGF-1

    JohnnyB

  4. #4
    men, get to the point.
    you are anchored.

    you said textually (literatim,verbatim):

    "nor is IGF-1 elevated by the use of HGH"

    -----------------------------------------
    and i posted:

    The Journal of Clinical Endocrinology & Metabolism Vol. 88, No. 11 5221-5226
    2003, by The Endocrine Society.

    "High Dose Growth Hormone Exerts an Anabolic Effect at Rest and during Exercise in Endurance-Trained Athletes
    M. L. Healy, J. Gibney, D. L. Russell-Jones, C. Pentecost, P. Croos, P. H. Sönksen and A. M. Umpleby
    Department of Diabetes and Endocrinology, GKT School of Medicine, St. Thomas Hospital, London, United

    r-hGH-treated

    ------------------ Baseline --------- 1wk-----------4 wk--------- /Placebo-
    IGF-I (nmol/liter) 24.6 ± 3.0 / 89.6 ± 12.21-- 106.3 ± 16.41/ 25.8 ± 2.7-- 25.4 ± 2.7-- 25.2 ± 2.6
    fT3 (pmol/liter) 5.1 ± 0.3 6.0 ± 0.12 6.1 ± 0.22 4.8 ± 0.2 4.9 ± 0.2 4.8 ± 0.1
    fT4 (pmol/liter) 15.5 ± 1.5 11.5 ± 1.02 10.6 ± 0.92 15.8 ± 1.6 15.6 ± 1.7 15.8 ± 1.5
    Testosterone (nmol/liter) 18.3 ± 3.2 18.5 ± 3.4 18.5 ± 3.3 16.7 ± 2.6 16.3 ± 2.6 16.4 ± 2.2
    Glucose (mmol/liter) 4.7 ± 0.3 5.5 ± 0.5 5.3 ± 0.2 4.5 ± 0.4 4.2 ± 0.2 4.4 ± 0.3
    Insulin (mU/liter) 7.9 ± 1.6 22.6 ± 3.92 16.0 ± 9.32 6.0 ± 0.3 5.6 ± 1.9 9.3 ± 2.4
    HOMA IR 1.4 ± 0.2 5.1 ± 1.02 3.3 ± 0.62 1.1 ± 0.4 1.0 ± 0.3 1.6 ± 0.5
    Total cholesterol (mmol/liter) 4.3 ± 0.3 4.0 ± 0.5 4.1 ± 0.3 3.4 ± 0.3 3.3 ± 0.3 3.5 ± 0.6
    Triglyceride 1.1 ± 0.2 2.0 ± 0.5 1.3 ± 0.1 0.6 ± 0.1 0.7 ± 0.1 0.5 ± 0.1
    LDL cholesterol (mmol/liter) 2.6 ± 0.3 2.2 ± 0.3 2.3 ± 0.3 1.6 ± 0.4 1.6 ± 0.3 1.6 ± 0.5
    HDL cholesterol (mmol/liter) 1.2 ± 0.1 1.0 ± 0.1 1.1 ± 0.1 1.5 ± 0.1 1.5 ± 0.1 1.7 ± 0.2
    Body weight (kg) 74.4 ± 1.1 76.5 ± 1.72 77.9 ± 1.62 74.9 ± 3.4 74.9 ± 3.4 74.7 ± 3.3
    Lean body mass (kg) 57.6 ± 1.1 61.0 ± 1.22 61.6 ± 2.5 61.8 ± 2.4
    Total body fat (kg) 11.4 ± 1.4 11.6 ± 1.7 9.8 ± 1.9 10.1 ± 2.0
    Trunk fat (kg) 4.7 ± 0.7 4.5 ± 0.9 2.8 ± 0.9 2.8 ± 0.9

    There was no change in IGF-I levels in the placebo-treated group throughout the observation period. In contrast, in the r-hGH-treated group, IGF-I levels rose markedly, reaching levels outside the physiological range (P < 0.001; Table 2 ). These changes occurred within 7 d of commencing r-hGH administration and did not change further over the remaining 21-d period of r-hGH administration."

    ------------------------------------
    igf is elevated 4 fold ! from hgh.

    --------------------------------------------
    who is wrong?

  5. #5
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    Quote Originally Posted by oswaldosalcedo
    There was no change in IGF-I levels in the placebo-treated group throughout the observation period. In contrast, in the r-hGH-treated group, IGF-I levels rose markedly, reaching levels outside the physiological range (P < 0.001; Table 2 ). These changes occurred within 7 d of commencing r-hGH administration and did not change further over the remaining 21-d period of r-hGH administration."

    ------------------------------------
    igf is elevated 4 fold ! from hgh.

    --------------------------------------------
    who is wrong?
    It looks like you are, didn't you post that HGH was a waste, but this prove it raises IGF-1, which is a good thing when looking for muscle growth, so this would make your point of HGH being a waste, de-bunked.

    But explain to me how this applies to LR3 IGF-1, the original point of this thread?

    JohnnyB

  6. #6
    i said that igf is good thing ?

  7. #7
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    Quote Originally Posted by oswaldosalcedo
    i said that igf is good thing ?
    Okay, but you are also trying to say LR3 is bad or what?

    JohnnyB

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