Gynecomastia: Etiology, Diagnosis, And Treatment

[*Narkissos*]

Drugs that induce gynecomastia by known mechanisms:

Estrogen-like, or binds to estrogen receptor:

Estrogen vaginal cream
Estrogen-containing embalming cream
Delousing powder
Digitalis
Clomiphene (Clomid bros...Clomid )
Marijuana

Stimulate estrogen synthesis:

Gonadotropins
Growth Hormone (Dammit... )

Supply aromatizable estrogen precursors:

Exogenous androgen (This should read aromatisable exogenous androgens ~Nark)
Androgen precursors (ie androstenedione and DHEA)

Direct Testicular Damage:

Busulfan
Nitrosurea
Vincristine
Ethanol (Yes you boozers.. the alchy DOES DAMAGE!)

Block testosterone synthesis:

Ketoconazole
Spironolactone
Metronidazole
Etomidate

Block androgen action:

Flutamide
Bicalutamide
Finasteride (yup...)
Cyproterone
Zanoterone
Cimetidine
Ranitidine
Spironolactone (repeat offender)

Displace estrogen from SHBG:

Spironolactone (repeat offender)
Ethanol (the booze does it again )




Drugs that cause gynecomastia by uncertain mechanisms:

Cardiac and antihypertensive medications:

• Calcium channel blockers (verapamil, nifedipine, diltiazem)
• ACE Inhibitors (captopril, enalapril
• b blockers
• Amiodarone
• Methyldopa
• Reserpine
• Nitrates

Psychoactive drugs:

• Neuroleptics
• Diazepam
• Neuroleptics
• Diazepam
• Phenytoin
• Tricyclic antidepressants
• Haloperidol

Drugs for infectious diseases:

• Indinavir
• Isoniazid
• Ethionamide
• Griseofulvin

Drugs of Abuse:

• amphetamines

Other:

• Theophylline
• Omeprazole
• Auranofin
• Diethylpropion
• Domperidone
• Penicillamine
• Sulindac
• Heparin

[briansauras]

Drugs that induce gynecomastia by known mechanisms:

Estrogen-like, or binds to estrogen receptor:

Estrogen vaginal cream
Estrogen-containing embalming cream
Delousing powder
Digitalis
Clomiphene (Clomid bros...Clomid )
Marijuana

So clomid/marijuana can make gyno worse?

[briansauras]

So clomid/marijuana can make gyno worse?

..................