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Originally Posted by
big k.l.g
IMHO it depends on the doses and the type of drugs you're running. Ok we already established that nolva significantly reduces 3rd gen A.Is blood concentrations, meaning running both together is NOT optimal, right? Well, no not really. As I said before other factors must be considered, most importantly the drugs being used.
First let’s say it's your standard testosterone, EQ cycle (500 and 400mg respectively). In this case the letro/nolva combo (.5-1mg/10-20mg) would be ok. If need be just adjust the letro or nolva dosage.
2nd: If it's a cycle with hefty amounts of test and 19-nors, especially tren, IMO the nolva should be dropped (because of its pro progestinic properties) and letro (because it’s anti-progestinic) should be used only.
For PCT I think both should be used with a gradual taper off the A.I.