I am 36 and always have been skinny. I recently did my second cycle and it is crazy! I actually thickened my wrists and ankles by a noticable difference. It is cool but kind of freaky. I gained nearly 2" in my ankles and over 1" in my wrists. Some of the gains in my arm came from the muscles but I swear my bones got larger as well. Not akromeglea (SP) as it did not effect my face. YET!