WRONG!Originally posted by Joe Young
if tthe compund is ingested it will pass thru the liver twice as opposed to once with injection...
It just takes a different path
The blood supply to and from the liver
Blood enters the liver by two separate routes:
1) The hepatic artery which brings freshly oxygenated blood to the liver. Within the liver the artery divides into fine branches which supply blood to the fine bile ducts. This blood passes on to special capillaries, called sinusoids, which take blood to every cell.
2)The portal vein which carries blood containing nutrients from the stomach and intestine to the liver. The portal vein also carried blood from the spleen.
The portal vein divides into very fine branches which drain into the sinusoids.
The blood leaves the sinusoids by the hepatic vein and returns to the heart
So either way if injecting or taking something orally(17aa) it is going to go in the blood stream just by different passages and go to the liver where by either method they go to the sinusoids and they are carried to all the cells. So just from this you can see that it DOESN'T pass twice. there is more technical data I have seen showing this but just reading the two passages to the liver sums it up IMO.
ThanksB&H
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