Methandriol dipropionate does not directly convert to estrogen, thus it has a low incidence of estrogen-related side effects, such as gynecomastia, water retention, and fat deposition, which are usually minimal if they occur. As Methandriol dipropionate has an androgenic component, typical androgenic-related side effects are possible: oily skin, acne, increased body hair, and scalp hairloss if prone to male pattern baldness.