
Originally Posted by
stupidhippo
as far as I have read this thread I haev come to the conclusion that its no differnet if its exo or endogenous test in this case... It just says it applies also to exogenous.. second thing: do we know how much muscle cells are dependant on this megalin uptake pathway? I mean there is talk about the kideneys, embryo etc.. but to what I have read the expression of the megalin proteins is very tissue specific.. third: dow e know that if there are any compensatory mechanims if indeed this megalin acticity can be altered? there are so many open questions here and I once again feel like u have too high hopes for this... but Im keeping my fingers crossed..