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Thread: A study showing resistance to steroids, coactivator defects

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  1. #1
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    Warrior21, what state are you in?

  2. #2
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    FL, why?

  3. #3
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    Taken from a study on PubMed. Basically backs up my theory that steroid coactivators have to do with resistance to roids;

    "Expression of steroid receptor coactivator-1 (SRC-1) was associated with nodal positivity (P < 0.05) and resistance to endocrine treatment (P < 0.001). "

  4. #4
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    Quote Originally Posted by Warrior21
    FL, why?
    Well, I know a doc that is cool with aas & versed as well, but unless your in S. Fl, that doesn't really help much. I would have to see if he is interested first though.

  5. #5
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    Quote Originally Posted by Iron-man
    Well, I know a doc that is cool with aas & versed as well, but unless your in S. Fl, that doesn't really help much. I would have to see if he is interested first though.
    I'm 100 miles north of Miami. I want to see him, extremely. Please tell him whatever necessary for him to want to see me. Please. I'll drive to whereever in FL, a couple of tanks of gas don't mean shit at this point.

  6. #6
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    " Therefore, tamoxifen may exert its effect not by a simple passive mechanism driven principally by competitive receptor antagonism but through the active recruitment of coactivator and corepressor proteins to produce a mixed transcriptional phenotype."

    I dunno if I posted in this thread or the other. But Tamoxifen has much to do with steroid coactivators. A dose of 300mg daily was suggested to me to help recruit more coactivators. Without coactivators, transcription will not happen. When transcription dosen't happen, your body will not produce more muscle.

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